- Music video Appears in "Got It Twisted" music video by Mobb Deep, directed by Benny Boom.
- (2004) Video game: Featured as a playable character in the game Def Jam: Fight for NY (2004).
- Music video: Appeared in Jonas Brothers video "Burnin' Up" as Joe Jonas' villain.
- (2007) Music video: Appeared in the video "Definition of an Ese" by Down aka Kilo.
- Music video: Appeared in the video for The Crystal Method's "Keep Hope Alive."
- (2009) TV commercial: ESPN Monday Night Football "This Guy" (parking garage scene)
- (2008) Music video: Appeared in the Tech N9ne Video "Like Yeah".
- (2011 - 2012) TV commercial (voice-over): Old El Paso taco sauce.
- (1996) Music video: Appeared in the Sepultura video "Attitude".
- (2008) Music video: Appeared in the Rehab video "Bartender Song (Sittin' in a Bar)".
- (2011) Music video: Appeared in the Maylene and the Sons of Disaster video "Open Your Eyes".
- (2013) TV commercial (UK): Old El Paso's smoky BBQ fajitas.
- (2013) Music video: Appeared in the Dustin Tavella video "Everybody Knows".
- (2014) TV commercial: "Old El Paso" taco sauce.
- (2014) Music video: Appeared in the Train video "Angel in Blue Jeans".
- (2015) Super Bowl 2015 TV commercial with Steve Buscemi (portraying Jan Brady from The Brady Bunch (1969)), Danny Trejo (portraying Marcia Brady), archive film appearances by Robert Reed (portraying Mike Brady) and Florence Henderson (portraying Carol Brady), and voiceover by Sean Kenin, for Snickers candy bar.
- (2016) Appeared as a prisoner in the music videos for the band Slayer - "You Against You" and "Pride in Prejudice".
- (December 2016) Commercial for "Sling TV"
- (November 6, 2012) Music Video For DJ Group 'The Ex-Girlfriends' -- (Song Title "We Are The Party") -- Cameo As Himself
- (2017) Music video for Thirty Seconds To Mars: "Walk On Water"
- (2016) Music Video: Appeared in the SadGirl video "Norma and Jessica".
- (2023) Cookbook, "Trejo's Cantina: Cocktails, Snacks & Amazing Non-Alcoholic Drinks from the Heart of Hollywood".
- (2024) TV Commercial: Del Taco
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