- Good friend of Eliza Dushku.
- She keeps a diary of her characters when she is filming.
- She is a triathlete.
- She has trading cards and two action figures designed after her character, "Glory", from the television series Buffy the Vampire Slayer (1997).
- Was dropped from her high-school cheerleading squad for refusing to sell hot dogs as part of a fundraiser (because Kramer is a staunch vegetarian).
- She has her own ringtone with the voice of "Courtney", her character from Bring It On (2000).
- When she was a child, she was Wendy's Mascot.
- Graduate of Delaware Hayes High School. Earned degree in acting from New York University. She credits her father, in whose office she worked, with teaching her the intricacies of business. She maintains a journal to keep her performances consistent.
- In the online diary that was kept by Roger Avary during the shooting of The Rules of Attraction (2002), Roger wrote "Clare Kramer, I love that girl, she's as quick as a whip".
- Co-owner, with her husband Brian R. Keathley, of Element, El Scorpion, and La Cantina.
- Her stunt double on Buffy the Vampire Slayer (1997) was Lisa Hoyle.
- Her son Sky's middle name LynLee is given after her sister-in-law, Stacey Lyn Keathley, who died on September 8, 2013, three months before her nephew was born.
- Gave birth to her 1st child at age 33, a daughter Gavin Keathley on February 4, 2008. Child's father is her husband, Brian R. Keathley.
- There is a Trivial Pursuit question about "Courtney", her character from Bring It On (2000).
- Gave birth to her 3rd child at age 37, a son Hart Keathley in May 2012. Child's father is her husband, Brian R. Keathley.
- While shooting The Mallory Effect (2002), she played pool with director Dustin Guy Defa and beat him.
- Gave birth to her 2nd child at age 35, a daughter River Marie Keathley on February 21, 2010. Child's father is her husband, Brian R. Keathley.
- Her company, "Defiance Entertainment", co-produced Tyson (2008). "Tyson" is a documentary, directed by James Toback, that covers the life of notorious World Champion boxer Mike Tyson.
- Born in Atlanta, Georgia, but grew up near Columbus, Ohio.
- Gave birth to her 4th child at age 39, a son Sky LynLee Keathley on December 11, 2013. Child's father is her husband, Brian R. Keathley.
- Each Christmas, she goes to the church with her family then wanders in the city admiring the lights. She and her little sister still hide in the stairs to see her parents putting the gifts under the tree. In the morning they all have a big breakfast together when they choose what they eat and when they open their presents. They then play cards.
- Her two cats are called Zoey and Waker.
- May be reprising her role as Glory on Buffy the Vampire Slayer (1997) for season 7, according to the show's creator Joss Whedon. (September 2002)
- Mother, Sandy; father, Terry.
- Just starting to shoot The Fallen (2011) in Tennessee. (August 2005)
- Just finished filming The Gravedancers (2006) in Greensboro, North Carolina. (April 2005)
- In The Wrong House (2016), she is slapped and gagged by Allison McAtee.
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