- Was one of the 20 original The Goldwyn Girls, along with Betty Grable, Paulette Goddard and Ann Sothern.
- She was divorced from Ali Ipar for the first time in 1951 when he began his compulsory Turkish army service because Turkish law forbids commissions to men married to foreigners.
- After ex-husband John Gilbert died in 1936, she made 14 movies in 16 months.
- Failed seven screen tests for the lead in Red-Headed Woman (1932), which went to Jean Harlow.
- Like most actors and actresses from then and now, she was a very active member of the Democrat Party and donated much of her time and money to many liberal causes (such as the Civil Rights Movement and the creation of The United Nations) and political candidates (including Franklin D. Roosevelt, Henry Wallace, Adlai Stevenson, John F. Kennedy, Robert F. Kennedy, and Jimmy Carter) during her lifetime.
- Coached by Roger Edens her soprano voice was used to introduce the Cole Porter song "I've Got You Under My Skin" to film audiences in the MGM musical Born to Dance (1936), singing the song to James Stewart.
- Her brother Stanley Briggs was married to Buddy Ebsen's sister and dance partner Vilma Ebsen.
- Very good friends with Cesar Romero and Joan Crawford.
- Her promising "A" MGM status was hurt following the death of Irving Thalberg. She subsequently was relegated to "B" films.
- Lovely but demure, and not especially ambitious or self-promoting, she was prodded by her parents, who were going through financial reversals, to skip her initial plans on a music education at UCLA and pursue film work.
- Her third husband Ali Ipar ventured into a misguided Turkish shipping business that eventually put him behind bars. Virginia was a major contributor to the business.
- According to Scott O'Brien's biography entitled "Virginia Bruce: Under My Skin," and his accompanying article on Virginia for Classic Images (February, 2010), Virginia was "discovered" by director William Beaudine when the young beauty accompanied her aunt, a clothing designer, to the home of a client, Mrs. Beaudine. Virginia played the piano and sang for him that day. Paramount, under Beaudine's suggestion, took an option out on her and placed her in walk-on and bit parts, her first being Beaudine's Fugitives (1929).
- Portrayed soprano Jenny Lind in The Mighty Barnum (1934) and a character loosely based on Florenz Ziegfeld Jr.'s mistress Lillian Lorraine in The Great Ziegfeld (1936).
- Her daughter Susan Ann Gilbert was born in 1933. She also had a son, Christopher Ruben, in 1941.
- She was the daughter of Margaret Mary (Morris) and Earll Frederick Briggs. Her great-grandson is actor Hutch Dano.
- Pale-eyed blonde in lead Hollywood roles during the '30s to mid-'40s, though often in "B" entries as well.
- Cousin of actress Ruth Hart.
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