- Has played a Nazi foil for Harrison Ford twice, in Force 10 from Navarone (1978) and Indiana Jones and the Last Crusade (1989). In both movies, his character ends up in a vehicle falling off a cliff.
- Has played a Nazi in Indiana Jones and the Last Crusade (1989) and a Jewish survivor of the Holocaust in Apt Pupil (1998).
- He was brought up by a single mother from Kilkenny Ireland.
- He and his Harry Potter and the Deathly Hallows: Part 1 (2010) co-star Bill Nighy both played General Friedrich Olbricht in dramas depicting the 20 July Plot to assassinate Adolf Hitler: Byrne in The Plot to Kill Hitler (1990) and Nighy in Valkyrie (2008).
- Considered for the roles of Roger Derebridge, Dr. Bukovsky. Lamson, Kelly and Dr. Armstrong in Lifeforce (1985).
- Father of Allie Byrne, but - despite a popular misconception - is no relation to Gabriel Byrne.
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