- He was the 14th and 17th Brazilian President, from 1930 to 1945 and from 1951 until his suicide in 1954.
- Grandfather of Getúlio Vargas Neto (Manuel's son), Celina Vargas Peixoto (Alzira's daughter) and Cândida Vargas (Lutero's daughter).
- Father of Lutero Vargas (1912-1898), Jandira Vargas (b. 1913), Alzira Vargas (1914-1992), Manuel António Vargas (1916-1997) and Getúlio Vargas (1917-1943).
- Brother of Protásio Vargas, Virtiato Vargas and Benjamin Vargas (1897-1973).
- Son of Manuel do Nascimento Vargas and Cândida Dorneles.
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