- Was supposed to have a solo musical career but canceled it when her record label dismissed her work as "too noir". She reunited her alternative rock band Garbage for a new album called "Not Your Kind of People". Garbage self-released the album on their new independent label, Stun Volume Records.
- Has reported that she used to cut herself as a teenager, even keeping a Swiss Army Knife in her boots, and has since used her celebrity status to bring awareness to the dangers of self-mutilation.
- Singer for the band Garbage
- In 2005, she revealed that she has the condition body dysmorphia, which may be the root of the depression which she has mentioned previously.
- She quit smoking after her husband's nephew died of cancer at age seven
- Her favorite singer is Frank Sinatra
- Joined the cast of Terminator: The Sarah Connor Chronicles (2008) as a regular cast member. (2008)
- Was a model for Calvin Klein.
- She had a cyst removed from her vocal chords during the Beautiful Garbage period.
- In the music video of "The World is Not Enough". Shirley Manson played a robot replica of Shirley Manson who kills the real Shirley Manson and takes her place. In Terminator: The Sarah Connor Chronicles (2008), Shirley Manson played Catherine Weaver, A T-1000 liquid metal Terminator.
- Is asthmatic.
- Her band Garbage has performed with American ska rock band No Doubt and Shirley has performed with Gwen Stefani on her tour.
- She dropped out of high school at 16. Since then, she has been in bands such as 'Autumn 1904', Wild Indians, Goodbye Mr Mckenzie and Angelfish.
- She has an orange Fender Stratocaster which she named "Rita".
- As of 2009, Lulu, Sheena Easton, and Manson (singing with Garbage) are the only Scottish artists to have sung 007 title songs, respectively: The Man with the Golden Gun (1974), For Your Eyes Only (1981), and The World Is Not Enough (1999). Ironically, neither movie featured fellow-Scot Sean Connery as James Bond.
- Her father was a biology teacher, her mother a singer.
- Lead singer, lyricist, guitarist, and co-producer on Garbage's five albums - the 1995 debut release "Garbage", 1998's follow-up "Version 2.0", 2001's "beautiful garbage", 2005's "Bleed Like Me, and 2012's "Not Your Kind of People". These albums have sold over 17 million copies to date.
- Ranked #47 in Stuff magazine's "102 Sexiest Women in the World" (2002).
- She is the author of the handwriting in Garbage's debut album.
- She had piano lessons as a child.
- Her favourite movie is Oldboy (2003).
- Her band, Garbage, went on an extended hiatus in late 2005, although they have worked together, infrequently, since.
- Promoting her new album "Bleed like me" (Available in music stores since April 11, 2005) all around Europe. (April 2005)
- Has an older sister, Lindy, and a younger sister, Sarah.
- Her divorce from sculptor husband Eddie Farrell became final in 2005. They had been separated since 2003.
- She was in the theater group when she was in high school
- She was the lead singer of Angelfish by the time she was discovered by Butch Vig and Steve Marker.
- Recording solo works with producer David Arnold, while on a break from Garbage. (April 2006)
- Of Clan Gunn.
- Her former husband is a sculptor.
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