She is married in January 2015. In the fall of that year, she reported on her blog that she gave birth to the first child.
In 2004, she made her voice actor debut in the anime series Aishiteruze Baby.
In 2006, she had her first main character role as Ringo Noyamano in Air Gear.
In 1997, when Ise was in her third year of elementary school, she was impressed in the anime movie Princess Mononoke and watched in the movie theater and wanted to be involved in a work that impressed people.