From 9/6/75 - 9/4/76 there was a live action show known as Ghost Busters. After the Ghostbusters film was a hit, Filmation put out an animated updated version of the show, the Original Ghostbusters in 1986. In the live show The Ghost Busters were a trio (Jake Kong, Eddie Spencer, and Tracy, the gorilla) that dealt with ghosts and other supernatural creatures. At the beginning of each episode, the trio get a taped message outlining their new mission. Once the message plays, the recording self destructs (ala Mission: Impossible). But unlike Mission Impossible, they never manage to get rid of the recording before it explodes.
The Ghost Busters then head out to find, capture, or get rid of the supernatural being. In almost every case, the various creatures end up in the old castle. The various creatures they encountered included vikings, Dr. Jekyll and Mr. Hyde, vampires, gypsies, werewolves, and of course, various ghosts.