Following an angry response from some audience members at the January 2016 Sundance premiere, a few festival reviewers purposefully spoiled the film in detail so as to deter animal lovers from seeing the film.
Heather Matarazzo turned down a possibility to reprise her role of Dawn Wiener from Welcome to the Dollhouse (1995). She was replaced by Greta Gerwig.
According to director Todd Solondz, the title character was portrayed by four dachshund show dogs but personally found them to be "dumb".