In an interview on ITV's Loose Women (1999), Whoopi Goldberg made a public plea to Maggie Smith that the role of Mother Superior was being held just for her and could not be played by anyone else. Whoopi expressed her willingness to accommodate Maggie by moving production to the United Kingdom if necessary to make things easier for her. However, Maggie passed away in September 2024, at the age of 89.
Title of recent draft is "Sister Act 3: Old Habits Die Hard".
Whoopi Goldberg met Pope Francis and found out that he was a Sister Act fan. When Whoopi invited the Pope to make an appearance in this movie, Francis said he was open to the idea, but it would depend on his schedule.
In an episode of The View (1997) that aired on May 20, 2024, Daisy Ridley expressed her wish to appear in a musical production, which is a lifelong dream of hers. Whoopi Goldberg then invited her to be in this film.
Cast members of the first two films unable to return include the late Ellen Albertini Dow, Carmen Zapata, Pat Crawford Brown, Susan Johnson, Ruth Kobart, Susan Browning, Edith Diaz (Choir Nuns), Mary Wickes (Mary Lazarus), Rose Parenti (Sister Alma) and Maggie Smith (Mother Superior).