Based on a novel by Phyllis Bottome, Colbert and McCrea are progressive psychiatrists who try to improve patient treatment, against the wishes of the local "Send 'em to the padded cell" Nurse Ratched type (Esther Dale). Unfortunately, the new and improved treatment seems to consist of Claudette getting up in the patient's face, grinning like a jack-o'-lantern and saying, "I'm your friend!" That would make me catatonic for sure.
Joan Bennett, as McCrea's wife, feels threatened by his closeness with Colbert. McCrea expects to be the new head of the institution, but the board chooses a conservative outsider (Boyer). If you aren't expecting a hate-turns-to-love vibe for Boyer and Colbert, you haven't watched enough movies. To get revenge on Boyer, McCrea starts an affair with Boyer's nutso sister (Helen Vinson). Charles Boyer and Helen Vinson are the least likely siblings this side of Dean Martin and Wendy Hiller in Toys in the Attic, and we never learn why one talks like Paris, France, and one talks like Paris, Texas.
Gregory La Cava is a fine director of romantic comedy, but this film needed an Edmund Goulding or John Cromwell, someone who could develop the domestic melodrama implicit in this material. All of the "sane" people come close to breaking down at one point or another, and that could have been the unifying theme behind the script. The pacing is off, and the script is too talky. The four stars are effectively cast, and several rounds of script revision and perhaps a different director might have made this a much better film.
One of the mental patients (the one who keeps saying "I'm Carrie Flint!") is played by Jean Rouverol, who would be blacklisted and eventually would write for the soaps.