Unlike the other Superman cartoons, this film has the characters and the Daily Planet set explicitly in New York City, rather than in the City of Metropolis.
For a 1940s cartoon, in a time when crude racial stereotypes were common, this film has a remarkably fair depiction of a Native American character. Although he is a fanatic in his cause, the villain is also a well dressed and spoken Native American man who only has a darker skin tone and slightly longer hair to signal his ethnicity.