It could be argued that the 1940's were something of a golden age for the B movie in America -at least in quantity terms - and several studios arose to make a great many cheap pictures for double bills and the sleazier end of the market . Monogram pictures were one such company and they strove with Universal for the horror end of the spectrum although with fewer resources . Like other such pictures The Ape gives a leading role to a horror icon , Boris Karloff ,while featuring unknowns, and untalented ones into the bargain, for the supporting parts . He plays Doctor Adrian who is regarded with suspicion by the small town locals but is revered by a young woman ,the wheelchair bound Frances Clifford whose paralysis he is striving to cure .His favoured method is by injection of spinal fluid but he is running out of the stuff till fate takes a hand .A giant ape escapes from the visiting circus ;unknown to the townsfolk he is shot .Adrian skins the dead beast and goes out at night dressed in the skin ,killing to obtain victims so he can continue the treatment . Karloff is his usual excellent self ,this time playing the scientist rather than a creation of a scientist ,and the script is quite sharp in its depiction of small town narrow mindedness .The ape suit is better than usual in this type of picture with this type of budget and this is a decent little horror number