In a case of life mirroring art, Martha Vickers (Valerie) passed away at age 46 before the other main members of the cast. Unlike the heart disease her character had in the film, she suffered from esophageal cancer. Of the remainder of the main cast, Rosemarie Stack (Fritzie) lived the longest, to age 86, passing away in January 2019.
In a very similar turn of events, in real life, Eve Miller, who played Marsha, Attempted suicide on 21 July 1955 (a few weeks after the movie released) at her Hollywood apartment, after an argument with her fiance.