This show was truly a family affair because Julie London was at the time married to Bobby Troup and had been hired by her previous husband Jack Webb, who was the series' creator and producer.
The radio call sign KMG365, which is said whenever Station 51 is responding to a call, is still a valid FCC call sign licensed to the LACoFD. It appears on the station patches for the crew at Station 127, which was used as the filming location for Station 51.
After the series, Jim Page, considered as the father of modern EMS and served as a series consultant, offered Randolph Mantooth the opportunity to train and become a Firefighter with the Los Angeles County Fire Department. He turned it down, but only after much reflection.
Dixie McCall, R.N. served as an Army nurse at a "M*A*S*H" unit in the Korean War.
The series is popularly credited for encouraging the widespread adoption of paramedic programs across North America.