The original BBC serials were not shown on American television. As a result "Quatermass" was unknown to potential U.S. audiences. As was done with the previous two movie adaptations, the title was changed. Twentieth Century Fox released this in the United States as "Five Million Years to Earth" (1967).
In the London Underground, there are quite a few posters from other Hammer projects such as The Reptile (1966), Dracula: Prince of Darkness (1966), and The Witches (1966), as well as My Fair Lady (1964) and Hotel (1967), on the station walls. An old, partially-ripped poster for Sex and the Single Girl (1964) can be seen on the wall opposite the entrance to Hobbs End station.
Director Roy Ward Baker subsequently looked back on the film as one of the happiest shoots of his career.
When Dr. Quatermass is picking at the eyeball of the dead Martian creature in his laboratory, the pupils of the compound eye are a rectangular slot shape rather then round like a human eye. This is reminiscent of a goat's eye, a creature that, for centuries, has been associated with witchcraft and sorcery.
A Sony CV-2000B Videocorder - a very early and primitive form of videotape recorder - is on display during the sequences in which the Martian race memory is both recorded and later played back to the skeptical military.