First of two back-to-back sci-fi/horror films for Barbara Carrera, who appeared in the following year's The Island of Dr. Moreau (1977). Both films were produced by Sandy Howard and included three of the same make-up department personnel.
The movie covered some of the same thematic territory that director Ralph Nelson had previously examined in his earlier film Charly (1968).
For some reason, at some point after the film's release, the film became treated as public domain in America. Floods of inferior-quality releases have been floating around the market, usually sourced from either the original U.S.A. Home Video VHS or a lower quality source.
Re-released in the US as "Created to Kill".
Joyce Brothers: As herself at a party but portraying a biologist rather than her actual profession as a psychologist.