During his opening guitar solo in "Further On Up the Road", Eric Clapton's guitar strap came off. To compensate while he fixed it, Robbie Robertson spontaneously played a brief solo of his own.
Every camera but one ran out of film during Muddy Waters' performance of "Mannish Boy." It resulted in the longest shot of the film, while Martin Scorsese scrambled to get the film cans reloaded.
The infamous cocaine drop hanging from Neil Young's left nostril was airbrushed out by Martin Scorsese.
Bob Dylan decided he didn't want to be in the film 15 minutes before he was due on stage. He didn't want it to compete with "Renaldo and Clara (1978)," which was still in theaters. Bill Graham, owner of the Winterland, intervened, and Dylan relented. He would only allow the last two songs of his performance to be filmed.