Originally, Alan Young was not considered for Scrooge, despite having played it in the album recording. Reportedly, it was because Walt Disney Productions believed he would not agree to do a voice for animated film. However, when Young learned about the film in production from a friend preparing to audition for the lead, he contacted the film company to request an audition. The resulting audition was successful and Young learned about the studio's reason for not contacting him. In reaction, Young responded, "Hey, I worked in television for five years with a talking horse. At this point in my career, nothing's beneath me." As it happened, Young was praised for the role and continued to voice Scrooge McDuck throughout his life.
This would be the last Mickey Mouse cartoon where Clarence Nash provides the voice of Donald Duck as Clarence Nash passed away in 1985, his voice notably sounds weaker here from old age. This is also the first of the Mickey cartoons where Wayne Allwine provides the voice of Mickey Mouse, though Allwine had actually first voiced Mickey Mouse in 1977 in Mickey's brief animated appearances from the television series: The New Mickey Mouse Club.
On the original 1975 LP which served as inspiration for this film, the Ghost of Christmas Past was Merlin from The Sword in the Stone (1963) and the Ghost of Christmas Future was the Evil Witch from Snow White and the Seven Dwarfs (1937).
Of all the songs on the original album, only "Oh What A Merry Christmas Day" made it to the animated cartoon. The rest of them - including one sung by Ebenezer Scrooge that was called "How Christmas Ought To Be" - were all dropped, and the lyrics were rendered into normal dialog.