Producers intended to use the medley from the cast's nightclub show for the big musical number near the end of the film. The medley included brief passages from many well-known show tunes. Due to Doris Fish's death and the high cost of the rights to even fragments of those songs, the scene had to be post-dubbed, with a different song and alternate singers.
Most of the film was shot in Doris and Ginger's flat at 422 Oak Street San Francisco, CA.
During production Doris was making a good living as a call boy and funding for the film came from their earnings. Doris once said "Who said you couldn't make a film on a prostitute's salary."
The principal photography of "Vegas in Space" spanned 18 months, but it took Fish and Ford eight years to raise the funds to complete the film.
Doris Fish, who co-wrote the script and starred in the main role, also designed the sets, costumes, makeup and hair, and miniatures.
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