As the part of Holly hadn't been cast, Whoopi Goldberg suggested her close personal friend, Drew Barrymore. The two have been friends since Barrymore visited the set of The Color Purple (1985) in 1985.
The band playing in the bar in Arizona is The Indigo Girls singing their hit "Joking".
Niecy Nash's debut.
The three main actresses are ten years apart in age. Whoopi Goldberg was born in 1955, Mary-Louise Parker was born in 1965, and Drew Barrymore was born in 1975.