The Winston gorillas in were so authentic, few people viewing the film ever realized that the animals were not real. "One of the greatest compliments I got from a friend," said Paul Mejias, "was when he said: 'I saw Instinct. Which were the real gorillas and which were yours?' That said it all." "The combination of the art and technology that went into our gorilla heads and suits," added Stan Winston, "the gorilla performances of the actors in those suits, and the fact that they were shot in a natural environment resulted in some of the best gorilla work I've ever seen. We'd had to go through a learning curve on Congo. But with Instinct, we nailed it."
After takes with Cuba Gooding, Jr., Sir Anthony Hopkins would routinely say "Show me the money!" in reference to Cuba's character in Jerry Maguire (1996).
Sir Anthony Hopkins' wig in the opening scenes was made from cat hair mixed with minx.
Features two Oscar winners: Sir Anthony Hopkins and Cuba Gooding, Jr. Donald Sutherland won a special Oscar (non competitive) in 2017.