The bottle of Dreamatol that Jeff Daniels takes out in the beginning of the movie (the first pills he takes in the film) has instructions that read: "For the relief of pain at its source, take as many pills as you can swallow until dreams overtake your perception of reality. Be cautious of the amount only when concerned with returning to reality. Otherwise, take the entire bottle for a complete disconnection from the pain of existence." Under the trademarked name Dreamatol it is described as a Dream Enhancer/Fever Reducer, even though the only ingredient listed is Ibuprofen.
Jeff Daniels is barefoot for the entire film.
The DREAMATOL pills that Ed shakes into his hand and then swallows in the beginning of the film are orange colored SweetTarts.