The bosses name, like previous two games and games after this (save from The House of the Dead: Overkill) is taken from Tarot cards, more specifically the Major Arcana section (Death, Fool, Sun, and (modified from The Wheel of Fortune) The Wheel of Fate).
Interestingly, despite using "3" during the game's development, the official title of the game is The House of the Dead III, making it the first game in the series to use Roman numerals.
With the appearance of Lisa Rogan, this is the first game in the series to have Woman as Playable Character. This would later be followed by Kate Green in The House of the Dead 4.