Snoop Dogg filmed a cameo appearance, but his scene was deleted. In an interview with Kermit the Frog on The Late Late Show with Craig Kilborn (1999), Kermit stated that because of Snoop's involvement in Doggystyle (2001), it was considered inappropriate to have him appear in a Muppet movie.
This film marks the first time that Janice speaks since the death of Richard Hunt. Another of Hunt's characters, Scooter, had a line in Muppets from Space (1999), which was voiced by his brother Adam Hunt.
This movie was first broadcast on NBC. Many references to the network are made throughout the film. Whenever the movie airs on other stations, all NBC references are edited out.
This is the first Muppet movie where Eric Jacobson does Frank Oz's roles of Fozzie, Piggy and Animal. Sam The Eagle is performed by Kevin Clash.
When Daniel (David Arquette) is sitting at his cubicle in heaven, there's a photo of Courteney Cox (Arquette's then-wife) on his desk.