Big-city girl Lacey Burrows moves from the bustling metropolis of Toronto, Ontario to the small farming community of Dog River, Saskatchewan when she inherits her late aunt's coffee shop, which is connected to Corner Gas, the local gas station, run by Brent Leroy. Lacey also meets several of the locals, including: Brent's parents, sensible and calm Emma and cantankerous old Oscar; Davis Quinton, senior officer of Dog River's two-person police force, and enthusiastic rookie officer Karen Pelly; Wanda Dollard, the intelligent but sarcastic employee of Corner Gas; and Hank Yarbo, the local idiot and Brent's best friend. Lacey's renovations on the coffee shop are met with much disapproval, mostly from Hank, who protests the changes. Until Brent intervenes.
His name is Marvin Drey and he's come to Dog River to check up on a few things concerning Corner Gas after a rather heated phone conversation with Oscar. Thinking that his only way out of jail, (which no one said he was going to in the first place), is a zany ploy, Oscar enlists the help of, of all people, Hank.
Lacey feels sluggish since moving to Dog River, seeing as she's not done Pilates lately. So, she offers a free class to anyone willing to attend. But, the only one who shows up is Davis, (because it's free). After all, why would anyone want to do exercises named after the guy who killed Jesus? (At least that's what some people in Dog River think.) Meanwhile, Oscar takes rather morbid steps in order to avoid being buried in a cheap-looking coffin, he decides to build his own.
When Wanda's tooth hurts and nobody is willing to kick her in the jaw, she makes an appointment for the dentist in Saskatoon. But somebody must babysit her hell-raising six-year-old son Tanner, and nobody in town is willing to, as many have incurred the boy's wrath. Finally, in trying to impress Lacey, Brent agrees to watch Tanner, at which the town places bets on how and when he will be injured. Lacey soon joins Brent in trying to tame the little nightmare. In a moment of sheer desperation, Brent phones the only person who can possibly save the day: Emma.
With nothing better to do, Karen begins going through cold cases and soon attempts to find out who spray-painted "Grad '68" on the town's water tower, a Dog River mystery that has remained unsolved for many years. Meanwhile, Lacey's idea of putting the ancient Roman symbols for male and female on the bathroom doors confuses many into going through the wrong doors. Many of the men who see how beautiful the women's bathroom is are upset when Brent puts the old signs back on the doors. Unfazed by this fiasco, Lacey hopes to write for the town newspaper, "The Dog River Howler," but she finds that writing for them is not as easy as Hank, Davis, Emma, Wanda, and basically everyone else in town makes it seem.
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Dog River's Mayor Fitzy tries to figure out a way to attract more tourists, and soon settles on Hank's idea of building the World's Biggest... Thing. Unsure of what to build, Fitzy's grandmother suggests, that because of Dog River's farming heritage, the town build the World's Biggest Hoe! It could be coming out of the ground, covered in soil and be the World's Biggest Dirtiest Hoe. Brent completely disagrees, but can't bring himself to tell Fitzy's grandmother why Dog River can't build a great big dirty hoe. Oscar has his own problems though, he thinks that the lovely Lacey has a crush on him.
When Lacey's ex-fiancée Stephen (Peter Oldring) visits from Toronto, Hank thinks she is being stalked by an obsessed lunatic, so he poses as her boyfriend to protect her. Meanwhile, Davis and Karen try to track down this "stalker," spinning his reputation out of control. Meanwhile, Emma tries to get Oscar to see a doctor for his annual checkup.
Brent's cousin Carl (Mike Wilmot) visits and pushes all his buttons, so Brent tries to prove to everyone just how big a jerk Carl is. Oscar tries to boycott the liquor store because Wes will not give him $1.20 for his old empties which are beer bottles no longer used. Meanwhile, Hank is unprepared for Dog River's annual talent show.
Davis gets a serious case of cell phone envy when he sees that Brent has a smaller one than he does. Soon, the two attempt to outdo one another by buying a smaller one than the other one has, then a smaller one, then a smaller one, and so on. Meanwhile, Oscar becomes addicted to the thrill of winning little stuffed animals on the new claw game in the bar and soon decides to seek help for it.
Upset to hear a comedian who once visited Dog River repeat a joke he told him when he was there, Brent plans to have the last laugh when he learns the comedian is returning to Dog River to do a show. Hank wants to do a set for comedy night as well, but cannot think of any material. Meanwhile, the ladies start a book club, which Brent makes into a movie club when he joins.
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Karen and Hank go on a fishing trip together at which she learns he is a different person when he fishes. Brent and Lacey engage each other in a battle of wits with the help of the new roadside sign. Oscar tries to prove his memory is as good as it ever was, prompting Brent and the whole town to have a little fun at his expense.
The Dog River hockey team, The River Dogs, find out their goalie, Brent, feels unappreciated and is considering playing for a rival team, The Stonewood Saints. With no coach either, Lacey steps up and helps The River Dogs to play one of their best games ever. They tie. Emma pressures Oscar to get rid of his clunker of a car, but Oscar insists the car is fine and the only clunker around is Emma.
Everyone is excited when they all take a trip to the Grey Cup in Regina, but since they all have to go with only one other person rather than as a group, problems arise. Emma is accused of stealing while at a dollar store with Wanda. Oscar with Hank, finds that a friend of his, who owed him money has passed on. And so, decides to steal his belt just as the paramedics and police arrive. Davis and Karen lose their tickets, so Davis tries to buy from a scalper only to find out that she's actually an undercover police officer posing as a prostitute and he gets himself arrested. And finally, Brent and Lacey run out of gas in the middle of nowhere, despite the fact that Brent owns a gas station. Thus, no one gets to see the Grey Cup at all.