This anime was a lot of fun. The overall plot is sort of rambling, but it's a great ride. It's one of the sci-fi-western genre, similar to Trigun, although the characters (four females who fight crime in Tokyo) reminded me of the main characters from Bubblegum Crisis. It's heavy on the gun and mecha action, and there's a mystery about one of the characters and her origins that is nicely resolved at the end. And if you like commentaries, there were commentary tracks for six episodes in the DVD set.
The music is excellent. The opening theme ("Loosey") is one of the most memorable I've ever heard.
That said, there was a lot of fan service, several allusions to gay love, and a good amount of violence, so it's definitely not for the kids.
Looking forward to the OVA.