Florence is facing surgery in Denmark. Depressed, she wishes she was dead, so her husband Robert could marry her sister. Thomas and his mistress plan a cozy week-end. They have no idea that his wife Christine is stalking them on the train.
Little Peter finds a gun and the loot of a bank robbery in a train compartment. He alarms the grown-ups, but they don't believe him. Since he can identify the robbers he takes more drastic measures to draw the attention of the authorities.
Felix binds and gags a railway employee, steals the valuables of the sleeping car passengers while they are dining, and leaves the train before they realize what happened.
An arrested conman is transferred on a train and guarded by two detectives. Soon he tries to bribe them by offering them 500,000 marks that his attractive accomplice in the next compartment is carrying.
Heinz and Ulli escape from a correctional facility, board train, and dodge the ticket collector. But when Heinz steals the purse of one of the nice girls they meet Ulli intervenes.
On the train from Hamburg to Rome two elderly ladies who love to read crime novels meet two gentlemen and decide to play a game: Let's smuggle this little parcel containing, say, cocaine across the Austrian border. What if we are caught?
On a train bound for Basel law firm employee Näglein happens to meet his boss Schwarz who is traveling with his employee Marion. Attempting to hush up their illicit affair Schwarz fires Näglein. But that is just one of Schwarz's problems.
Cops Kupfer and Torff watch a drug courier take two suitcases from a locker. When they arrest him in a train compartment, no drugs can be found. How did he switch suitcases? And who threw them off the train? The chase is on.
Wanted jewel thief Dörpinghaus is traveling to Zürich and flirting with a well-known model. He doesn't realize that two cops are looking for him on the same train - but they don't know what he looks like.
Elsa has been working on the express to Vienna for many years, she is well-liked by her co-workers. So it's tough for conductor Fragner who has to officially inform her that due to her age she has been relegated to office duty.
Nurse Nanni is on the way to meet her bridegroom - the match was made via a marriage agency. But when the man she knows only from a photograph happens to step into her train compartment he has never heard of her.
In a train compartment Eastern spies Laura and Ivan meet German agents Eva and Y for a battle of wits. For Eva to solve the case of a compromised arms depot is, literally, a crossword puzzle.
Detective Krapp investigates the murder of a woman who was thrown from a train. Main suspect is her brother Vincenz, and a week later Krapp takes him on the same train journey to find out what actually happened.