The Big 4 are the adopted children of Petrus, who has trained them to be perfect assassins well atleast 3 of them as the youngest one mostly is a bait. Petrus is murdered leading to the big 4 to go on hiding while his actual daughter becomes a police officer and is obsessed to solve his murder. How the daughter teams up with the 4 to take revenge on their father's killer, forms rest of the story.
The tone never gets serious with constant funny lines thrown around. Many jokes don't land correctly, but the loud comedy somehow carries the story forward while the bloody action set pieces take care of the rest. Much of the jokes fall under the silly category but the action set pieces gets more fun whenever they get silly which should be credited for the innovativeness. The story is built up for a sequel so the main reason for the conflict is still kept unrevealed.