Among the interviewees are Nelleke van der Crogt, Nicolette van Dam and Loretta Schrijver. International singer Leona Lewis performs her new single 'Happy' and later gets stuck in the elevator.
Among the guests are Peter van der Vorst, Viola Holt, the finalists of Benelux' Next Top Model, the cast of the touring musical Chicago, Kim-Lian, and Wendy van Dijk.
Irene introduces the fashion line for Spring 2010. Jan Kooijman discusses the 4000th episode of GTST and his experiences on the show. Mark Rutte talks about his career.
Carlo and Irene attend the highly publicized premiere of Mary Poppins, the Dutch musical. Other guests include Eddy Zoey, discussing his new program with Beau van Erven Dorens, and Gordon, discussing his new book.