It's always nice to see more anthology shows on TV. Femme Fatales is probably the first erotica/crime anthology show since The Hitchhiker.
Femme Fatales shares The Hitchhiker's wildly uneven nature, as it luxuriates in gunplay, murder, and exploitation of women, all while trying to give lectures on violence and the exploitation of women (see the "Girls Gone Dead" slam with Charlie O'Connell pitch-perfect as the sleazy producer). The main difference between the two shows is the adrenaline jolts of humor and pure insanity which kept The Hitchhiker going. Femme Fatales usually takes itself very seriously, and often seems very flat, in everything from lighting to acting. It's half-baked noir. Worst of all is they continue to have a host who can barely read her lines and who was presumably hired solely for a British accent and for her large breasts. Imagine Alfred Hitchcock Presents hosted by the local sweater girl.
When you watch old Hitchhiker episodes, you can ogle the absurd fashions, hairstyles, pulsing synthesizers, and general paranoid cocaine blindness which makes up so much of 1980's TV. You get an extra kick from nostalgia. You don't get that with Femme Fatales. The show represents the directionless blandness of so much of today's pop culture.