Ryan's eccentricities (talking to plants, playing with puppets, live action role-playing) were characterized by Russell Nauman as coping mechanisms for Ryan's loneliness as a gay man.
Michael Huntsman, Alisha Peats, and Jasmine Hester previously worked together on the web series Redwood (2013) before joining twenties: the series.
Cameron's affinity for basketball comes from Chris Lamica and his real-life experiences playing professionally in the ABA.
Andrew Miller, who plays the male stripper Elton, also served as the stunt and fight coordinator for the show.