To be honest, I didn't know anything about semaglutide before watching this episode. After checking about it, I found that they showed everything kinda right and in a fun way. I like when they make the show Cartman-centric, showcasing all his bad sides. The good part is that this special has all five lead kids and Randy doing his crazy stuff like always.
I haven't heard any songs by Lizzo and don't know much about the cartoons of the sugary brands, but this episode was still fun for me.
Overall, it's a good, fun episode for South Park fans but probably not for Lizzo fans and Pakistani people.
I'm waiting for the 27th season of South Park. It's been more than a year-please just release it ASAP.