Version 6                                                                                                                                                  Page 1 of 5
Pandemic expansion guide
                                                                       by Jacob Berggreen
This guide is intended to help “Pandemic” players getting an overview of the many expansions/challenges.
The guide first contains a quick overview of the expansions.
Then, the guide shows compatibility between expansions.
Then, the guide helps setting up the base game (with expansions roles and events).
Then, the guide helps setting up each expansion by comparing to the base game setup.
This does not replace the rule books.
Table of contents
1.   Expansion overview .................................................................................................................................................. 2
2.   Expansions compatibility .......................................................................................................................................... 3
3.   Base game setup guide ............................................................................................................................................. 4
4.   Expansions setup guide ............................................................................................................................................. 5
Version 6                                                                                      Page 2 of 5
1. Expansion overview
 Expansion/challenge         Summary
 Virulent strain             One of the diseases becomes a virulent strain.
 from “On the brink”
                             This strain of disease becomes harder to fight.
                             Epidemic cards have effects on the virulent strain.
 Virulent strain             Adds two new “Virulent strain” epidemic cards.
 from “In the lab”
 Mutation                    A new mutated (5th) disease appears.
 from “On the brink”
                             The mutated appears randomly in new cities or cities already affected with
                             other diseases.
                             To prevent running out of cubes, you have to treat the mutated disease
                             often, since there are only 12 cubes.
 Mutation: Worldwide panic   Modifies “Mutation” from “On the brink”.
 from “In the lab”
                             The mutated disease is in play from start.
                             The mutated disease appears in greater number.
                             The mutated disease can be treated less often as there are now 24 cubes
                             instead of only 12.
                             The mutated disease is harder to cure.
 Bio-terrorist               One player controls a 5th disease and plays against the other players.
                             The bio-terrorist secretly notes his whereabouts.
                             The other players gain knowledge about the bio-terrorists’ whereabouts
                             when he/she is “spotted” (in the same city as other player) or “sighted”
                             (uses direct or charter flight).
                             3-5 players.
 Lab                         Cures must be developed in a lab by “characterizing”, “sequencing” and
 from “In the lab”           “testing” them. Then, the cures can be finalized at research stations.
 Solo game                   One player together with an imaginative CDC player against the diseases.
                             The CDC player may perform 1 of 5 possible actions in between the real
                             player’s actions.
 Team game                   2 or 3 teams race to achieve most prestige.
                             Prestige is gained by a team when they find cures and eradicate diseases.
 Quarantines                 By ordering quarantines in cities, the players can stop the growth of
 from ”State of emergency”   diseases temporarily.
                             As an action, players can quarantine cities.
                             This makes the game easier.
 Hinterlands                 In the hinterlands of certain cities, diseases now spread from animals to
 from ”State of emergency”   humans and into the connected cities.
                             The hinterlands are represented like cities on board extensions.
                             On every turn, you roll a die and a disease cube may appear in the
                             hinterlands.
                             Players can share knowledge easier in the hinterlands (knowledge about
                             animal diseases).
 Emergency events            Bad things happen when emergency events occur.
 from “State of emergency”
                             Emergency events are added to the player deck, like epidemic cards.
 Superbug                    A new resistant (5th) disease is in play.
 from “State of emergency”
                             You can’t treat the disease until a cure has been found.
                             When a cure has been found, vaccines are used to treat the disease.
                             Must be played together with “quarantines”.
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2. Expansions compatibility
This table shows which expansions are compatible with one another.
The matrix is symmetric.
               Virulent                                              Quaran- Hinter- Emergency
                        Mutation Bio        Lab     Solo    Team                               Superbug
               strain                                                tines   lands   Events
 Virulent
                             X        X       X        X       X       X       X        X         X*
 Strain
 Mutation         X                           X        X       X       X       X        X
 Bio              X                           X                                X        X
 Lab              X          X        X                X               X       X        X         X*
 Solo             X          X                X                        X       X        X          X
 Team             X          X                                         X       X        X          X
 Quarantines      X          X                X        X       X                                  X**
 Hinterlands      X          X        X       X        X       X       X                X          X
 Emergency
                  X          X        X       X        X       X       X       X                   X
 events
 Superbug         X*                          X*       X       X      X**      X        X
Legend
 * Special rules when combined
 ** Must be combined
Version 6                                                                                               Page 4 of 5
3. Base game setup guide
This table shows the setup in the base game, including all possible roles and events from expansions.
Later, in the “Expansions setup guide” section, this table will act as the offset.
                         Roles (1 or more cards per player)          Events (2 cards per role)
                         Base game                                   Base game
                         Contingency planner                         Resilient population
                         Dispatcher                                  Forecast
                         Medic                                       Airlift
                         Operations expert                           Government grant
                         Quarantine specialist                       One quiet night
                         Researcher
                         Scientist                                   On the brink
                                                                     Special orders
                         On the brink                                New assignment
                         Bio-terrorist                               Rapid vaccine deployment
                         Archivist                                   Re-examined research
                         Containment specialist                      Borrowed time
                         Epidemiologist                              Commercial travel ban
                         Field operative                             Remote treatment
                         Generalist                                  Mobile hospital
                         Trouble shooter
                                                                     In the lab
                         In the lab                                  Improved sanitation
                         Field director                              Sequencing breakthrough
                         Local liaison (no lab actions)              Infection zone ban
                         Pilot
                         Virologist                                  State of emergency
                         Epidemiologist (in the lab version)         Emergency response
                         Researcher (in the lab version)             Advance team
                                                                     Local initiative
                         State of emergency                          Resource planning
                         Colonel                                     Sample delivery
                         First responder                             Emergency conference
                         Gene splicer                                Infection rumor
                         Pharmacist
                         Veterinarian
                         Medic (superbug version)
Version 6                                                                                                     Page 5 of 5
4. Expansions setup guide
For each expansion, this table shows the changes to the roles used and “other changes” like changes to events and
which parts to include from the expansion boxes.
The information is relative to the table in the “Base game setup” section above.
 Game mode                             Roles                         Other changes
 Virulent strain
 from “On the brink”
 Virulent strain                                                     Exchange epidemic cards with “Virulent strain”
 from “In the lab”                                                   version.
 Mutation                                                            Include the 2 “mutation” infection cards.
 from “On the brink”                                                 Include the 3 “mutation” event cards.
                                                                     Include 12 purple disease cubes.
                                                                     Include purple “discovered cure” indicator.
 Mutation: Worldwide panic                                           As in “mutation” from “On the brink”.
 from “In the lab”                                                   Add 12 purple disease cubes.
 Bio-terrorist                         Include “Bio-terrorist”       Include “location sheet”.
                                                                     Include pencil.
                                                                     Include black pawn.
                                                                     Include 12 purple disease cubes.
                                                                     Include purple “discovered cure” indicator.
 Lab                                   Exclude “Field operative”     Include the lab extension board.
 from “In the lab”                     Exchange “Epidemiologist”     Include sequence cards.
                                       Exchange “Researcher”         Include lab actions reference cards.
 Solo game                             Include “CDC” role card       Exclude “Special orders”
                                       Exclude “Dispatcher”
                                       Exclude “Researcher”
                                       Exclude “Epidemiologist”
                                       Exclude “Local liaison”
 Team game                                                           Exclude “Hidden pocket” virulent strain
                                                                     epidemic card if combined with “Virulent strain”
                                                                     Include team reference card.
                                                                     Include team goal cards.
                                                                     Include team bonus cards the same way as
                                                                     epidemic cards when creating the player deck.
                                                                     Include team awards.
 Quarantines                           Include “Colonel”             Include “Local initiative” event.
 from ”State of emergency”                                           Include 6 quarantine markers if “Colonel” role is
                                                                     in play.
 Hinterlands                           Include “Veterinarian”        Include “Hinterlands” boards at the side of the
 from ”State of emergency”                                           base game board.
 Emergency events                                                    Include “Emergency” event cards the same way
 from “State of emergency”                                           as epidemic cards when creating the player
                                                                     deck.
 Superbug                              Exchange “Medic”              Include “quarantines” expansion.
 from “State of emergency”                                           Include superbug bonus cards the same way as
                                                                     epidemic cards when creating the player deck.
                                                                     Include 24 purple disease cubes.
                                                                     Include vaccine doses.
                                                                     Include 4 vaccine factories.
                                                                     Include superbug reference cards.
                                                                     Include purple “discovered cure” indicator.