Uterine Myoma
Uterine Myoma
on Uterine
Myoma
Submitted by:
J-Jireh Abar
Kierzner Caores
Submitted to:
Jeselo O. Gorme RN
Clinical Instructor
Introduction
Uterine myomas also called “fibroids” are tumors that grow
from the wall of the uterus.
Uterine fibroids are noncancerous growths of the uterus that
often appear during childbearing years.
The wall of the uterus is made of muscle tissue, so a fibroid is a
tumor made of muscle tissue. The fibroids start off very small,
actually from one cell, and generally grow slowly over years
before they cause any problems.
Some fibroids go through growth spurts, and some may
shrink on their own. Many fibroids that have been present during
pregnancy shrink or disappear after pregnancy, as the uterus
goes back to a normal size.
Fibroids range in size from seedlings, undetectable by the human
eye, to bulky masses that can distort and enlarge the uterus. They
can be single or multiple, in extreme cases expanding the uterus
so much that it reaches the rib cage.
Objectives
General Objectives:
After the Case presentation the level 3 students will know the disease
process and the general idea of uterine myoma
Specific Objectives:
After an hour of discussion the BSN-3 students will be able to:
Biographic Data:
HPN
Legend:
The patient states that health is very important and thus she gives
emphasis to it and her attention is fully dedicated. Patient also states
the presence of stress due to the condition and the expenses needed
for the treatment, she has no complains about the health care facility
or of the health care team and no alternate beliefs and traditions
related to health are stated.
V. SLEEP-REST PATTERN
VI.COGNITIVE-PERCEPTUAL PATTERN
Prior to admission the patient has no auditory impairment no
difficulties in learning and no changes of memory but she complains of
body weakness
IX.SEXUALITY-REPRODUCTIVE PATTERN
The patient is sexually active
X. COPING STRESS PATTERN
Physical assessment
A.General Survey
- Patient was conscious and coherent
- Appears anxious
B.Vital Signs
- Temp: 36.9 °C - RR: 20cpm
- Pulse: 79bpm - BP: 110/80mmhg
C.Integumentary
- Color is brown with no palpable lesions
- Moist skin surface
- Nail beds are pinkish with no inflammation
D.Eyes
- Conjunctiva is transparent, moist, no swelling/ lesions noted
- Cornea is transparent
- Iris is dark brown in color
- Pupils accommodated
- Eyelids intact with no swelling/ lesions noted
E.Ears
- Ear canal intact with little cerumen
- Able to hear soft words
- No discharges on both ear canals
- No tenderness upon palpation
F.Nose
- Nasal mucosa is intact
- No nasal flaring
- Nostrils are patent
G.Mouth
- Lips are slightly moist upon inspection
- Gums and tongue is pink
- Hard and soft palate intact
H.Neck
- Symmetrical without scars
- No palpable lymph nodes
I.Respiratory
- No nasal flaring
- No use of accessory muscle
- RR @ 20cpm
- Bilateral Chest expansion
J.Brest
- Sizes appropriate for age
- Symmetrical
- NO erythema
K.Abdomen
- No tenderness upon palpation
- No lesions/ scar
- No erythema
L.Reproductive
- Able to urinate regularly
- Appropriate for age
M.Muscuskeletal
- Ambulatory
- Able to move
- Can flex and extend body parts
N.Neurological
- Patient able to speak words clearly and logically
- Able to understand instructions and conversation
Developmental task
Theory:
-Erik Erikson’s theory of psychosocial development
-The adolescent
-Identity versus Role confusion
Basic:
-during this stage, adolescents must bring together everything they have learned
about themselves as a son or daughter, an athlete, a friend, a fast-food cook, a
student, a scout, and so on, and integrate these different image into a whole
that makes sense. If adolescents cannot do so, they are left with role confusion;
that is, they are unsure of what kind of person they are and are uncertain what
they can do or what kind of person they can become. Some adolescent seek a
negative identity: being identified as a drug abuser or runaway may be
preferable to having no identity at all.
Actual:
-The patient is not confused about her identity.
Theory:
-Piaget’s theory of Cognitive development
-The Adolescent
-Formal operational thought
Basic:
-When this stage reached, adolescent are capable of thinking in terms of
possibility what could be rather than being limited to thinking about what
already is . This makes it possible for adolescents to use scientific reasoning or
also understand deductive reasoning, or reasoning that proceeds from the
general to the specific.
Actual:
-The patient uses scientific reasoning.
Theory:
-Freud’s Psychoanalytic Theory
-The adolescent
Basic:
-During this stage Freud termed the adolescent period the “genital phase”
Freudian theory considers the main events of this period to be the
establishments of new sexual aims and the finding of new love objects.
Actual:
-The patient is on the process of what this stage needs.
Theory:
-Kohlberg’s Theory Moral Development
-The adolescent
-Postconventional development
Basic:
-In this stage, adolescent can carry out self-care measures even when someone
else is not present when they enter in this stage because they can understand
not only the importance of the measures to themselves but also the principle
that certain thing should be done simply because they are right.
Actual:
-The patient is able to understand and respect other people.
Definition of Terms:
Uterine Myoma is a growth of fibrous tissue in the uterus, usually a fibroma ,
fibromyoma or leiomyofibroma.
It is a benign encapsulated uterine tumor. The tumor may develop in the wall of
the uterus or be attached to a stalk of tissue originating in the wall. Symptoms
may include menstrual disorders and are also likely to be related to the location
of the tumor with respect to neighboring organs.
Uterine Myomaarise from the muscle tissue of the uterus and can be solitary or
multiple in the lining, muscle wall and outside surface of the uterus.
Uterine myoma is a benign growth of smooth muscle in the wall of the uterus. A
uterine myoma is a solid tumor made of fibrous tissue, hence it is often called a
'fibroid' tumor.
Etiology
Predisposing Factors Basic Actual
Age Fibroids are most √
common in women who
are their 30s through
early 50s. (After
menopause, fibroids tend
to shrink.) About 20 -
40% of women age 35
and older have fibroids of
significant enough size to
cause symptoms.
Race Uterine fibroids are
particularly common in
African-American
women, and these
women tend to develop
them at a younger age
than white women.
Heredity Family history, having a √
mother or sister who had
fibroids, may increase
risk.
Early Menarche Women whose first √
period was before age 10
are more likely to have
uterine fibroids.
Nulliparty nulliparity appeared to
be the most potent risk
factor for uterine fibroid
in the
population studied.
The ovaries are a pair of small glands about the size and shape of almonds,
located on the left and right sides of the pelvic body cavity lateral to the superior
portion of the uterus. Ovaries produce female sex hormones such as estrogen
and progesterone as well as ova (commonly called "eggs"), the female gametes.
Ova are produced from oocyte cells that slowly develop throughout a woman’s
early life and reach maturity after puberty. Each month during ovulation, a
mature ovum is released. The ovum travels from the ovary to the fallopian tube,
where it may be fertilized before reaching the uterus.
Fallopian Tubes
The fallopian tubes are a pair of muscular tubes that extend from the left and
right superior corners of the uterus to the edge of the ovaries. The fallopian
tubes end in a funnel-shaped structure called the infundibulum, which is covered
with small finger-like projections called fimbriae. The fimbriae swipe over the
outside of the ovaries to pick up released ova and carry them into the
infundibulum for transport to the uterus. The inside of each fallopian tube is
covered in cilia that work with the smooth muscle of the tube to carry the ovum
to the uterus.
Uterus
Vagina
The vagina is an elastic, muscular tube that connects the cervix of the uterus to
the exterior of the body. It is located inferior to the uterus and posterior to the
urinary bladder. The vagina functions as the receptacle for the penis during
sexual intercourse and carries sperm to the uterus and fallopian tubes. It also
serves as the birth canal by stretching to allow delivery of the fetus during
childbirth. During menstruation, the menstrual flow exits the body via the
vagina.
Fertilization
Once the mature ovum is released from the ovary, the fimbriae catch the egg
and direct it down the fallopian tube to the uterus. It takes about a week for the
ovum to travel to the uterus. If sperm are able to reach and penetrate the ovum,
the ovum becomes a fertilized zygote containing a full complement of DNA.
After a two-week period of rapid cell division known as the germinal period of
development, the zygote forms an embryo. The embryo will then implant itself
into the uterine wall and develop there during pregnancy.
Menstruation
While the ovum matures and travels through the fallopian tube, the
endometrium grows and develops in preparation for the embryo. If the ovum is
not fertilized in time or if it fails to implant into the endometrium, the arteries of
the uterus constrict to cut off blood flow to the endometrium. The lack of blood
flow causes cell death in the endometrium and the eventual shedding of tissue
in a process known as menstruation. In a normal menstrual cycle, this shedding
begins around day 28 and continues into the first few days of the new
reproductive cycle.
Pregnancy
If the ovum is fertilized by a sperm cell, the fertilized embryo will implant itself
into the endometrium and begin to form an amniotic cavity, umbilical cord, and
placenta. For the first 8 weeks, the embryo will develop almost all of the tissues
and organs present in the adult before entering the fetal period of development
during weeks 9 through 38. During the fetal period, the fetus grows larger and
more complex until it is ready to be born.
Symptomatology
Signs and Symptoms Rationale Actual
Heavy Menstrual Bleeding The most common √
symptom is prolonged and
heavy bleeding during
menstruation. This is
caused by fibroid growth
bordering the uterine
cavity. Menstrual periods
may also last longer than
normal.
Menstrual Pain Heavy bleeding and clots √
can cause severe cramping
and pain during menstrual
periods.
Abdominal Pressure and Large fibroids can also √
Pain cause pressure and pain in
the abdomen or lower back
that sometimes feels like
menstrual cramps
Abdominal and Uterine As the fibroids grow larger, √
Enlargement . some women feel them as
hard lumps in the lower
abdomen. Very large fibroids
may give the abdomen the
appearance of pregnancy and
cause a feeling of heaviness
and pressure. In fact, large
fibroids are defined by
comparing the size of the
uterus to the size it would be
at specific months during
gestation.
Pain during Intercourse Fibroids can cause pain
during sexual intercourse
(dyspareunia).
Urinary Problems Large fibroids may press
against the bladder and
urinary tract and cause
frequent urination or the
urge to urinate, particularly
when a woman is lying
down at night. Fibroids
pressing on the ureters (the
tubes going from the
kidneys to the bladder) may
obstruct or block the flow
of urine
Constipation Fibroid pressure against the
rectum can cause
constipation.
Pathophysiology
Predisposing Precipitating
Factor Factor
>Age Etiology >High fat diet
>Race >Obesity
>Heredity >Anxiety/Stress
>Early Menarche >Oral
>Nulliparity Contraceptives
>Hormone
Estrogen
Replacement
Dominance or
Therapy
Increase estrogen >Coffee/Caffeine
S/Sx:
>Swelling of the
Proliferation of cells breast
in uterus >Depression
>Loss of sex
drive
>Dysmenorrhea
Overgrowth in the
endometrial lining
Myoma
Development of
uterine fibroid
S/Sx:
Uterine cavity >Pain
begins to stretch or >Increased
increase in size Pelvic Pressure
Interference in
the vascular
supply
Degeneration of S/Sx:
the interior part >Hypermenorrhea
of fibroid
Anemia S/Sx:
>Fast or abnormal
heartbeat
>Pale
Rapid Irregular
Heartbeat
Cardiac Arrhythmia
Congestive Heart
Failure
Bad Prognosis
DEATH
Medical Management
Ultrasound
An ultrasound probe is inserted into the vagina or over the pelvis on the
abdomen, and high-frequency sound waves reflect off the uterus and pelvic
structures. An image of the uterus is then displayed on a monitor and fibroids
are visualized.
Sonohysterogram
A water solution is injected into the uterus through the vagina and cervix, and an
ultrasound is then done. It then possibly shows uterine fibroids or other
abnormal masses in the uterus
Hysteroscopy
A tube with a lighted viewer on its tip (endoscope) is advanced into the uterus,
and a video screen shows the uterus interior. Hysteroscopy can detect uterine
fibroids projecting into the uterus, but cannot see any part of a fibroid in the
uterus wall or outside the uterus.
Uterine biopsy
A small piece of tissue (biopsy) taken from the uterus is used for examination if
the doctor suspects of a cancer and not a myoma is manifesting. A uterine
biopsy may be done through the vagina, or may require surgery.
Surgical Management
Endometrial Ablation
Surgery that destroys the lining of the uterus. It is used to treat small
fibroids inside the uterus. Two common ways of doing an ablation are
with a heated balloon, and with a tool that uses microwave energy to
destroy the uterine lining and fibroids.
Laboratory Results
Interpretation:
Decreased Hematocrit indicates anemia or hemorrhage due to persistent blood loss related to
abdominal uterine bleeding
Assessme diagnosis Planning Interventio rationale evaluation
nt ns
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usually with
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feelings or on current
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hyperplasia,
future
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endometrial
cancer.
Reference:
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intervention characteristics, of
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the client severity (0-10). medications,
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to report report changes of healing.
by pain scale
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*Administer *medical
analgesic and management
anti- for pain and
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pain
drugs as
prescribed by
the physicians.
Drug Study
Generic Name:
Ferrous sulfate
Trade Name:
Classification:
Iron Preparation
Dose, Route PO
freq: BID
MECHANISM OF ACTION
Elevates the serum iron concentration which then helps to form High or trapped
in the reticuloendothelial cells for storage and eventual conversion to a usable
form of iron.
INDICATIONS
• Prevention and treatment of iron deficiency anemia
• Dietary supplement for iron.
CONTRAINDICATIONS
• Hypersensitivity
• Severe hypotension.
ADVERSE EFFECT
• Dizziness
•N&V
• Nasal Congestion
• Dyspnea
• Hypotension
• CHF
• MI
• Muscle cramps
• Flushing
NURSING RESPONSIBILITIES
• Advise patient to take medicine as prescribed.
• Caution patient to make position changes slowly to minimize orhtostatic
hypotension.
• Instruct patient to avoid concurrent use of alcohol or OTC medicine without
consulting the physician.
• Advise patient to consult physician if irregular heartbeat, dyspnea, swelling of
hands and feet and hypotension occurs.
• Inform patient that angina attacks may occur 30 min. after administration due
reflex tachycardia.
• Encourage patient to comply with additional intervention for hypertension like
proper diet, regular exercise, lifestyle changes and stress management.
Classification: NSAID
Nursing consideration:
Adverse effects
GU: Nephrotoxicity
Nursing Considerations:
Nursing Practice
Knowledge, skills and ability should always be as one. It is an essential
aspect that we carry out nursing action and interventions bearing in mind its
underlying principle and standard for the plan of care that we provide to our
patients and clients.
Nursing Education
Knowledge about the disease process is hints in evaluating patients that
are at risk for the probable problem that may arise. This study aims to improve
and prevent further complications that may show the way to worst case
scenarios. As a nursing student it is important for us to know what are the
rightful actions and interventions that we can do in order to avoid and lessen
additional complications.
Journal Reading
Uterine fibroids (leiomyomas) represent the most common tumor in women.
These lesions disrupt the functions of the uterus and cause excessive uterine
bleeding, anemia, defective implantation of an embryo, recurrent pregnancy
loss, preterm labor, obstruction of labor, pelvic discomfort, and urinary
incontinence and may mimic or mask malignant tumors. By the time they reach
50 years of age, nearly 70% of white women and more than 80% of black women
will have had at least one fibroid; severe symptoms develop in 15 to 30% of
these women. Uterine fibroids in black women are significantly larger at
diagnosis than those in white women, are diagnosed at an earlier age, and are
characterized by more severe symptoms and a longer period of sustained
growth. Approximately 200,000 hysterectomies, 30,000 myomectomies, and
thousands of selective uterine-artery embolizations and high-intensity focused
ultrasound procedures are performed annually in the United States to remove or
destroy uterine fibroids. The annual economic burden of these tumors is
estimated to be between $5.9 billion and $34.4 billion.
Uterine fibroids are monoclonal tumors that arise from the uterine smooth-
muscle tissue (i.e., the myometrium). Histologically, fibroids are benign
neoplasms composed of disordered smooth-muscle cells buried in abundant
quantities of extracellular matrix. The cells proliferate in vivo at a modest rate.
Formation of the extracellular matrix also accounts for a substantial portion of
tumor expansion. Uterine fibroids are almost always benign.
A striking feature of uterine fibroids is their dependency on the ovarian steroids
estrogen and progesterone. Ovarian activity is essential for fibroid growth, and
most fibroids shrink after menopause. The sharp elevations and declines in the
production of estrogen and progesterone that are associated with very early
pregnancy and the postpartum period have a dramatic effect on fibroid growth.
Gonadotropin-releasing-hormone (GnRH) analogues, which suppress ovarian
activity and reduce circulating levels of estrogen and progesterone, shrink
fibroids and reduce associated uterine bleeding.
A limited number of genetic defects transmitted by germ cells have been
associated with familial uterine fibroid syndromes. Most notable are germline
mutations causing fumarate hydratase deficiency, which predisposes women to
the development of multiple uterine fibroids. In addition, a variety of somatic
chromosomal rearrangements have been described in up to 40% of uterine
fibroids. Recently, whole-genome sequencing showed that chromosomal
rearrangements are often complex, best described as single events consisting of
multiple chromosomal breaks and random reassembly. In an earlier study, a
somatic single-gene defect was found in a majority of uterine fibroid tumors;
this group of mutations affects the gene encoding mediator complex subunit 12
(MED12).
There are also genomewide differences in DNA methylation between fibroid
tissue and the adjacent normal myometrium. A large number of other molecular
defects involving transcriptional and posttranscriptional events, microRNAs
(miRNAs), and signaling pathways have also been described. Although some of
the effects of uterine fibroids on cell proliferation, apoptosis, and extracellular
matrix formation have been identified, little is known about their effects on
other cellular processes in fibroid growth, such as autophagy and senescence.
This review focuses on some recent developments in fibroid research, including
the role of stem cells, somatic genetic and epigenetic defects, and the action of
estrogen and progesterone and their cross-talk with various signaling pathways.
Reference:
American College of Obstetricians and Gynecologists. ACOG practice bulletin.
Alternatives to hysterectomy in the management of leiomyomas. Obstet
Gynecol. 2008;112:387-400.
Borkan J. Uterine Fibroids. In: Ferri F.: Ferri's Clinical Advisor. 1st ed.
Philadelphia, Pa: Mosby Elsevier; 2014 Section 1 U.
Katz VL. Benign gynecologic lesions: Vulva, vagina, cervix, uterus, oviduct, ovary.
In: Katz VL, Lentz GM, Lobo RA, Gershenson DM, eds. Comprehensive
Gynecology. 6th ed. Philadelphia, Pa: Mosby Elsevier; 2012:chap 18.
Rodriguez MI, Warden M, Darney PD. Intrauterine progestins, progesterone
antagonists, and receptor modulators: a review of gynecologic applications. Am J
Obstet Gynecol. 2010 May;202(5):420-8. Epub 2009 Dec 23. Review.
Moss J, Cooper K, Khaund A, et al. Randomised comparison of uterine artery
embolisation (UAE) with surgical treatment in patients with symptomatic uterine
fibroids (REST trial): 5-year results. BJOG. 2011 Jul;118(8):936-944