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Aomori ale E. him fetid monotone

meagre
Had Kim
supnadiafregmatie
*
ggl
:
.

* Non -

Hod Kim :
ggl .
multicenter

mobile
.

ggl :
-

medeenenosi ( la de akod )
ingestion demerged
-

'
-

devi

Somme B -

febo 38

transpire,tii nocturne
-

scodere lot in Ultimate 66mi

ponderous
-
-
.

*
biopsies exciziondo :
infiltration glossator
arhitecleera
ggl .

Reed CD 30
cell :

Steinberg -
:
nuclei bi -
multi nucleates
take
gigantoido Cdyo
rare Qisg
* IHC : camo
*
imunofenotipare '
flowatometsie :
puncgiemededero

Ly B : got .
CDs cdig igsupreggto
is: : : %:
•

Rx terbia :
compressive mediastinal Cdispnee ,
teese )
ecogrelsie ogamomegaliecspu.no
•
f-
hepatic )
:

amigdaa.am Naldayen
*
cere
* MALT

hermoleucograma
•
 org Uimfoide primate modena
-

times

Ong Uimfoide .

secondaire -

ggl
-

spina
-
MALT
- Imel lui
Waldayer
*
Biopic Osteo -

Medel bro
* FISH
simptme : anomie (
pale 'd , vestiges ,
icier ?
CHIS HDI )
trombocetepenie ,

laeoatozo +
Lymfopenie
•
bio Chimie :
-

era .

citelizo CTGO ITGP FAL )

,

enz .
celesta 20

*
Morken de imoturotumonalo LDH ( turnover T )
-

: -

acid
-

uric
-

K
STADIALIZARE
pzmiaoglobatima
-

M.M. ,
ademopatie /
organ afedat
STDs .

ademopatie +
organ
STD de
2 .
2
grggl .
distinct
aceea.si p
-

adiafsegsn .

STD de
3 .
2 t
ggl .

afectate ambekp.de diafragm .

STD 4 .
2
org extnaggl .

afectate
 Tnatamont

Redioterapie 140
Gg )

Pdiohimriofenapie -

bkormicino cfibnozo pulmonary

doxorubicin ccendiotexic )
-

vincristine cparestezii )
-

dexameleze.no ccorticolexpie )
cipnogosnfemidoctexicitatevezicalo)
-

cisplatin Cototexicitaletmefrctex )

* Chimie la
:
rezistento treatment

VIRAL
Ag etiologic
.
: -

E. barn
-
Hiv
-

Herpes tip 8
-

HTLµ

laecomii
Millom multiple
 MELON HOLM PLO

cell STEM

l l
B T
granule nongranular
:
Ly si
.

f tropism T

uterine
exec,
plasma cite
:
Medline

mutated proof .
meontndat
De ggl modena osoaso
-

a'diner →
-

'The in Modesto
plasmon
( anomie
proliferate
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,
tnombociteponie , leucopenia
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secrete fact activ
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osteoclast mail iostedizo

* menedonele osteoblast t denari
protein : osoase

nolde auto Ac deferment

hipaa in
hiperca :
bisfosfonatitnatament
*
parapnoteinem.ie :
ig
proteinuria Bence Jones

Waimate footie
.

ig :
electrospray N
pe
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tip peak h
imwnecectnofenezo
:
MM secretor de
ig . . . . .

biochimie
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f. renato hipaa
:
: Mee

Proteinase, creatinine tdeerena

acid uric

132 MM anomie
micro
globulin specif -

imp
LDH Ca
Kt
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ca RTL G Anemia Bone

function Hbd to lessons

Arthur Clerke
pwndgie Medeiros citologie
:

imewofonetipare Sfongitul copibriei

u
crane'll Methot de Molina

tnatament : .

pdichimioteopie
•

radiothapie
•
inhibitor de angiogenesis : antiemetic
taledomed Savino
2
carfezomigcbontezomidlcfoo.me lie >

protozoan : inhibitor de protozoan

autograft
•

*
hipervasozilate : TT ④ mesoderm
IgA
TVP ↳ se
primal de
AVC endosteum
TEP
hiperoagedabiletate
retiniom
test : U ion 200
 LLC

limfepnolifoativ cronic peste tooo 110000 ly nature

E. ban
imfec
L
. viral e :

Hiv
•

imunofonetipare Ly B : C.Dig a CDzz Me respond

Cdr to
Lyt :
apoptosis

poliadenepdtii
hepatesplenemegacia : 2140 om sub nedbord

•
cite genetics deco apax simptumelolegie
•
Bio cell saucitopenii
ex : trisomic 12

deletion 13g
delete ttp
a prognostic
:
negate :
afecteaze PS3

STADIALIZARE

1
. Ly og
t modelled

2 .

Ly Sg / rmoduvotorgerormegdie IADP

3 .

Ly tamemii I all of the above

Le .

Ly t tnormbocituponie I all of the above

tnatament :

Rituximab i to anti CDR,

Ibnutimcb :

↳
imhib de brute kimono

LGC

Miele proliferated Cronic ex : pdicilemia Vera

tnomboatemiaesontiab

Hate cell in tooele stediile de divisione

females sanguine deviates busta
me dubro
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proteins de geeziune
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de bhestico 30
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: 2e - -

peri Serie

imatinib :
rmoreierepie It chimed

Dasatinib
Poratinib LGC
LLC
tomboy tenia
-

MM
pdicitemia Vere Lirmfeome
CID
 LE OCEAN 'RE ACUTE

Leucermiile Acute Letmfoblastice ( LLA )

manifested clinic
Somme
gi simple me generate :
•

alterarea stories
generate
febo I see bfebrel foie infected explicabiho
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transpireten
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e'
mapetmto
-

in
scalene
greater
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datunaleimsuficient.ee
'

s
gi s medalare
• :

simdnom anemic :
aslenieiertijes , palone
simdnom imfafios pneumonia
'

amerine
:
-

simdnom
hernoagic petesii epistaxis herretoame
:
-

, >

preti footie leucemice

.

s dolerite
•

si s :

durai Boase
simoom tumour splemomegalie hepatomegalie
- :
,

adenopatii medeeneroase
im filtered SNC :
ee
fake vorsoturi
-

,
-

Sindh .
de Leno Stata
 AA
* Anemia Aplastic
-

pamcitopenie
-

modulo hematopoietic hipocelubro

Gpa 'm disparity a t tesutuuii hematopoietic
-

congenital
°
dobomdito -

primitivo
- toxic

* Rise infection gi hemoogic •

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§ simptome (
-

astenie , gatigabiwtate samestew ,

vatijii Satow
infect
,it
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sefngerotri CPLT sub 20.000)

seko aretes
pabare teg ae tonto
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purpure
}
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clinic
hernoogii
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stomatitis
gingivitis
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splenomegaly
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pt diagnostic
.
:
Biopsies osteo -

Medicare &
-

fregiuiksti crome20miale

cariotip Mechelen
-

* metetaexatt ciclosporin :
grefo contra gender
* Leucemiile Acute Mie loblastice LAM

-
cell .
blastice proliferate
}I
eritrea't
modulo
bogato cu
qonulecit
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,
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punctiemedulero cmielogremo
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tnatament
complete
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de anemisiwnii
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giefer de cell stem

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hematopoietic
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cyton 'm Arabinose 'd
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t
2 I
7- t 3 antracicu.no
 Leucemie Acute Limfoblastico LAL
-
anomie

tnombocitopenie
-

cell irmatene
limpblast 301
-

.
.

Leukemia Limfatico cronies LLC

-

hepatomegalie , splenomegalie
tnombocitopenie
-

anomie

limfocitozer TOOO -1
-

Leucemiea Acute rniebblasn.co LAM

-

conpi Auen
-

anomie , toomboatopenie
-

neutropenia , mieleblast 't

Leucemia Mielec do cnomico LMC

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r
splenomegacie
-

-
WBC : 80.000 t

Osimo filet basefilet

-
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former severer :

grega
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imunosupnesor
-

Metilpnednison
prima linie
GGAAI y
• :

Ciclosporin
GATT
ciclosporin
tinier
Androgens
.

• a 2-a .

Conticoterapie
Fact de -

cnegtene hematopoietic
•
trot -

adj :

tnomsfuzii concentrate i -

enitnocilene

plachetare
-

-
leuoalere

pnofilaxie infected
•

* Leucemia Acutes Limfoblastico LAL

-

ehimioterapie
-

allogpefa de celule see.se

autogrefa
-

•
conhcoizi :
Prednisone
Dexamelazeno
•
akaleizide vince vimcristina , Vin blastema
:

•
antnaciclime : imhib de topoisomerase 2
.

ag.alkibmyiileelofosfame.dk
•

•
anti -

folic :
Rnetotnexat
etape :
induction
-

consolidated
pnofelexianeeodere.br in SNC
-

intestinenee
* Leucoma Acuter Mieles lattices LAM
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ehimioterapie
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etape nemisiune
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completes
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consolidate , imtnetmene
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giefer de cell .

stemlsesratopoieticex
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Cytosim Anabimozid Cst ) t Danorubictmcz-3)

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* heucemia Mie bides cronies Lan c

Centaurea massif hematologic
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seeprimereaclemeipatobgice.ph -1
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chimioterapie Hidnoxiunea
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Basal
fan +
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vincristine t Doxoriubicina Dexasmetazona

allognefo *
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interferon
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imhibtinozimkimaza : imatinib
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Decitabima

* Police tenia Rubra Vera PRV

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flebotormii ( 300 -400Mt be 2 file)

-

fosfon radioactive 1232

-

ehimioterapie -

Hidnoxieuee
-

Pipo broman
-

Anagnelid
-

interferon
-

deficit mangal : -
Eee

songoori
-

hiperurieemie :
akopurinol
-
* Tsombocitemia TE
Esenhjalo
-

tnombocitafeneza
-

fosfennadioachu Pzz
-

Hidroxiuree
-

Pipo broman
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Anagnelid
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Interferon alga
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transfusion on concentrate
plachdenemoomek
Aspirin 300mg Hi
-

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cell
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nadiotesapie :
gge implicate
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.

extensor

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chimioterepia : Mapp t ABVD
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Pnocerbazima Vimbbstinh
P Pnednisom D Baconbasin

* LiMFOAME MALIAN E NON HODGKIN LIMN At -

monoterapie :
cbrambueil
Cicbrfosfamidh
pdichimiolerapie f
:
-

Doxorubicin
0
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redioterapie
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imunoterepie Interferon alfa

: Acrmeroclondi
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autograph cell
sage hematopoietic
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akoopefa
-
* deucemia Limfatico cronies LLC
-

await and watchin

Clorambucil
ag alkibnh
-
.
:

Cidofosfamidle
Vincristine Prednisone e
Cicbfosfamida
It
C
Ciclefosfamidh Doxorubicin
Vincristine
Op
vincristine 0

Prednisone P Prednisone
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analogs neeckozidici
. -

Fludarabima
-

Ac trnomoclomali - Rituximab
cell
transplant Stem
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splenectomies
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redioterapie
-

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redioteropie Cpt dureriosoase )

.

chirmiotoopia
Alexi man Xnelfabnt Poedmison
:

Cielofosfamidh
V vincristine
B BCNU
M
Megaton
c
liclofosfamide
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autegxga I
de cell .

sage
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prednisone
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splenectomies
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Cicbfesfomidh
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Ac rmoneeleneli
.
:
Rituximab
-

tonsfuzii eplachetene
 MIE LOM MULTIPLU

STADiARE, :
Salmon & Durie

STADIUL I :
toateeniteriik preterite
:

* Hb peste 10mg Ide

Ht 32%
↳
the
seen
peste
masa TUM
Cau
* sub
12mg Idl
* Rx : Sta .
oases Moomaw salt

plasmaatom soliton

* Pratima rmenocbmdo b new -

Seozute :

IgG sub Idl

5g
ig A sub
3g loll
124
P Bence .
Jones urimaro sub 4g de

STADiULImasmo.mnuenoo.AE
STADIUL II
* Hb y
pmeYfeaY
sub 8. rrmgldl

causerie peste
*
ezmgldl
* Rx :
kziuni osteocetice auansate

* Prot monotone :
IgG pesky ,
IgA peskrgldeb
Bona ones 12
peste gk4h
Subclasificenex
A :
Fungtie Renato Wormald
creatinine sub
2mg Idt
*B : Fund
,ne Renato Alienates
creatinine peste 2mg Ide
 LIM FOM HODGKIN & L MN H

¥iAL¥RE Ann Arbon -

STADIUL I impucerea
:

Sunni singer
•
quip ggl .

• Sta
limfoido c spline ,

ne
.

supra saw times ,

i.
Waldaya)
• tent .

extralimfatic

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tou 't
ggl
•
a 2 seen mai mulk .

•
impure leader prim antiguitar a ennui

singer organ the 't

extrelirmfatic

bdeace agipasteadiapegmulfSTADIULHIimpu.com
seen .

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'

ggl . de amber pork ale

dialpgsnuuei
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sup :
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,

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ggl pare-aorh.ci
. , , .

STADIUL I invaded
Mai mutton
org sautes extrdimfatice
• .

I
( nee
prim extension ) ggl .
 substantialize
* A :
absent somme B

* B :
presents * febres ( fores infect
*
transpire,hi nocturne
* scalene in
opeutate

* a :
absent somme biobgiceimflem .

* b :
preterite Somme bio .

inform
* VSH A
9
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globalism
 L L C

STADIALIZARE :
Rae .

s£④
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'

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* STADIUL 2 :
limfeutezo sgtmoduuo

.ie/hepaeomegoue*STADiUL3:limfocite2e
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.

teadperonfamtiegawe
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limfoutozo
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I
Spslenelhepatemegelie
+
tnornbocitopenie
Sub 100.0001mm
3
&
 STADIALIZARE : Bisset

A Hb
* STADIUL Peste to gldl In
: *
Tnormboate peste
100.009
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"

{
mm

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ariigge .

120 Umi

* STADIUL B In
: * Hb peste to
gldl
*
Itptnoiembguiean.es#ggeeo.o.oooinm*
61
'

tune

* STADIUL C : * Hb sub log loll tr

integument .mil
goggles
E
* :b egg;

32 Luni