MINISTRY OF HEALTH OF UKRAINE
ODESSA NATIONAL MEDICAL UNIVERSITY
DEPARTMENT OF PHARMACOLOGY AND PHARMACOGNOSY
METHODICAL INSTRUCTIONS
FOR THE PRACTICAL CLASSES
IN PHARMACOLOGY
TOPIC: LIQUID DOSED DRUG FORMS: SOLUTIONS, DROPS,
SUSPENSIONS FOR INNER USE, AEROSOLS, DRUG
FORMS FOR INJECTION
Act.head of department
prof. Rozhkovsky Ya.V._______
Odessa 2020
Unit 3. LIQUID DOSED DRUG FORMS: SOLUTIONS, DROPS,
SUSPENSIONS FOR INNER USE, AEROSOLS, DRUG
FORMS FOR INJECTIONS
I. Individual work
Control questions
1. Sol.s for inner use. Rules of calculation and prescription main and
officinalsol.s. Features of prescribing spirit and oil sol.s.
2. Concept about drops for inner use, as versions of sol.s for inner use. Officinal
and main prescriptions. Rules of calculation.
3. Suspensions for inner use. The characteristic and differences from sol.s. Rules
of prescription.
4. Dosage aerosols. Characteristic and rules of prescription.
5. General characteristic and the requirements showed to medicinal forms for
injections. Forms of release (an ampoule, Bot., syringes – tubes), advantages
and lacks. The solvents used for preparation of sol.s for injections. Rules of
prescribing officinal medicinal forms for injections (sol.s, suspensions,
powders). Features of prescribing main forms for injections.
6. Features of prescribing of patented and New Galen’s dosage sol.s.
List of practical works. Write prescriptions:
1) 200 ml. 10% of sol. Calcii chloridum (Calci chloride). 1 table spoon 3 times a
day. Calculate an SD for Calcii chloridum.
2) Dioninum, drops for inner use. SD – 0,01 20 drops 3 times a day for 10 days.
Write in developed and short form.
3) 10 ml. of 5% spirit sol. Iodum (Iodine). 5 drops at milk 2 times a day after meal
for 30 days.
4) Suspension “Maalox”, vial for 250 ml. 1 table spoon 4 times a day
5) Aerosol ‘Berotek’ 15 ml. One inhalation 3 times a day.
6) 10 ampoules, containing 1 ml. 0,1% sol. Atropini sulfas, injection S.C. 1 ml.,
account SD.
7) 10 vials, containing 500.000 units of Streptomycini sulfas (Streptomycin sulfate).
Powder for I.M. injections. 500000 units 2 times a day, dilute in 2 ml. 0,25% sol.
Novocain.
8) 500 ml. of sterile isotonic 0,9% sol. Natrii chloridum (Sodium chloride). Prescribe
500 ml. I.V.
9) 10 ampoules, containing 1 ml. 1% oil sol. Progesteronum (Progesterone). I.M.
injection, 1 ml.
10) 6 vials, containing 5 ml. 2,5% suspension Hydrocortisoni acetas
(Hydrocortisone acetate). For injection in the cavity of affected joint; 3 ml. 1 time
a week.
Tasks for self-control. Answer the following questions:
1) What are the rules for writing out the solutions and oral drops? Do we have
features when prescribe oil , alcohol and patented solutions?
2) How to calculate the concentration of the sol. from a single dose of the drug in dry
form, and conversely?
3) What are the features prescribing suspensions, emulsions for oral administration,
aerosols for inhalation?
4) What refers to dosage forms for injection? What are the requirements to impose
it? What are the rules for their prescribing?
5) What features prescribing dosage forms for injection in vials?
6) What are the features of prescribing organopreparations, dosage units of biological
actions?
7) What are the main features of prescribing dosage forms for injection?
II. Original practical work in class
1. To view the collection of drugs in liquid dosage forms.
2. To write prescriptions:
1) 180 ml. 33% of sol. Magnesium sulfate. 1 table spoon 3 times a day
2) 10 ml. 1% spirit sol. Nitroglycerinum. Take 2 drops on sugar under the tongue.
3) 5 ml. 0,125 % oil sol. Ergocalciferolum. Prescribe 2 drops twice a day.
4) 30 ml. Corvalolum. 30 drops on take.
5) 250 ml. 5 % suspension Salazopyridazinum. Inject like enema by 20 ml. before
night.
6) Aerosol ‘Ipradol’ 15 ml. Double inhalation 5 times a day.
7) 10 ampoules, containing 1 ml. of 24% sol. Euphyllinum (Aminophylline).
Prescribe by 1 ml. intramuscular 2 times a day. Count number of dry substance,
what is need for creating such concentration of sol.
8) 10 ampoules containing Heparinum by 5 ml. (1ml. – 5000ED). By 5000 ED S.C. 1
time a day.
9) 30 vials, containing powder for injection Benzylpenicillinum – natrium 1000.000
units. To dilute the contents of the vial in 2 ml. of 1% sol. Lidocainum before
injection, inject I.M. 6 times a day.
10) 10 vials containing 0,1 g of Lydasum (Hyaluronidasum). Before use the
contents of the vial should be diluted with 1 ml. 1% sol. of sterile Lidocainum.
Inject S.C. in the region of scar.
11) 800 ml. 5% sterile sol. of Glucosum. For manipulations.
12) 10 patented ampoules containing 1 ml. suspension ‘Zymosanum’. Inject I.M.
every other day.
13) Platyphyllini hydrotartras, SD – 0,005 in powder; tablets, drops for inner use,
in ampoules with 0,2 % sol., 1 ml. for S.C. injection.
