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02 Preparation 1 and 2

The document provides instructions for preparing paracetamol divided powders and compound effervescent powders, including lists of ingredients, equipment, procedures, and discussions of the products' descriptions, uses, and preparation methods such as spatulation, trituration, and sieving. The paracetamol powder is prepared by weighing and mixing ingredients then dividing the powder into individual doses, while the effervescent powder involves sieving, mixing, and dividing ingredients to produce a bubbling antacid when added to water.

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James Azurin
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712 views4 pages

02 Preparation 1 and 2

The document provides instructions for preparing paracetamol divided powders and compound effervescent powders, including lists of ingredients, equipment, procedures, and discussions of the products' descriptions, uses, and preparation methods such as spatulation, trituration, and sieving. The paracetamol powder is prepared by weighing and mixing ingredients then dividing the powder into individual doses, while the effervescent powder involves sieving, mixing, and dividing ingredients to produce a bubbling antacid when added to water.

Uploaded by

James Azurin
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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PREPARATION NO.

1: PARACETAMOL DIVIDED POWDERS Facsimile Label: Prescription Drug


PRE-LABORATORY DISCUSSION
Materials:
 Spatula
 Pill tile
 Mortar and Pestle
Formula:
Ingredients Original Amount Computed Amount
Paracetamol 3g 1.5 g
Lactose 5g 2.5 g
To make: 10 papelitos 5 papelitos

Compounding Procedure:
1. Weigh 3 g of paracetamol and 5 g of lactose accurately.
2. Triturate the two powders separately.
3. Mix the two powders by the spatulation method.
4. Place the powders on a pill tile and use the block and divide POST-LABORATORY DISCUSSION
method.
Paracetamol Divided Powders
5. Divide evenly into the required quantity.
6. Wrap in an individual white paper and put it in an appropriate  The individual dose has been packed separately and used as asn
container. analgesic and anti-pyretic.
7. Label the container.  Synonym:
o Acetaminophen pulveres
 Method/s to Prepare:
o Spatulation
o Trituration
 Type of Preparation:
o Solid dosage form
 Uses:
o Analgesic
o Anti-pyretic
Facsimile Label: Non-prescription Drug  Methods to Pulverize:
o Trituration
o Sieving
o Grinding
 Methods of Mixing:
o Trituration
o Spatulation
o Shifting
o Thumbling
 Types of Mortar and Pestle:
o Glass
 a non-porous surface
 intended for solution, suspension, and
ointments (smooth)
o Wedgewood
 a porous surface
 facilitate the comminution of crystalline solid
(rough)
o Porcelain
 used for soft, aggregates or crystals
 Types of Paper:
o Glassine
o Vegetable parchment
o Waxed
o Bond paper
 Product Description:
o should be composed in an organized way
o color/appearance, type of preparation, odor/taste, and
action after sensation/feeling/administration
o A white crystalline fine powder, odorless, and enclosed
in a white elegant paper.

PREPARATION NO. 2: COMPOUND EFFERVESCENT


POWDERS, USP
PRE-LABORATORY DISCUSSION
Materials:
 Spatula
 Pill tile Facsimile Label: Non-prescription Drug
 Mortar and Pestle
POST-LABORATORY DISCUSSION
Formula:
Compound Effervescent Powders, USP
Ingredients Original Amount Computed Amount
Sodium bicarbonate 30 g 12.5 g  to bubble as gas escapes
Potassium sodium  Synonym:
90 g 37.5 g
tartrate o pulveres effervescentes compositii
Tartaric acid 26 10.83 g  Method/s to Prepare:
To make: 12 papelitos 5 papelitos o Spatulation
o Trituration
Compounding Procedure:
 Type of Preparation:
1. Weigh all the ingredients accurately. o Solid dosage form
2. Sieve potassium sodium tartrate and sodium bicarbonate in a  Uses:
#60 sieve mesh separately. o Antacid
3. Mix the two powders by the spatulation method and divide into  Methods to Pulverize:
5 equal parts. o Trituration
4. Wrap the mixed powders in a white wax paper. o Sieving
5. Divide the tartaric acid into 5 parts and wrap in a blue paper.
o Grinding
6. Place in an appropriate container.
 Methods of Mixing:
7. Label the container.
o Trituration
o Spatulation
o Shifting
o Thumbling
 Types of Paper:
o Glassine
o Vegetable parchment
o Waxed
o Bond paper
 Product Description:
o A white amorphous powder, tasteless, odorless, and has
a bubbling effect when added to water.

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