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Drug Study 2

N-acetylcysteine works by splitting mucoproteins in the lungs, reducing viscosity of pulmonary secretions and facilitating removal by coughing or drainage. It is indicated for bronchodilatation before acetylcysteine treatment and protects against acetaminophen overdose hepatotoxicity. Potential side effects include nausea, vomiting, increased secretions or bronchospasm. Nurses should observe the rights of medication administration and monitor the patient's respiratory status and sputum.

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Joshua Selwyn Salazar
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369 views2 pages

Drug Study 2

N-acetylcysteine works by splitting mucoproteins in the lungs, reducing viscosity of pulmonary secretions and facilitating removal by coughing or drainage. It is indicated for bronchodilatation before acetylcysteine treatment and protects against acetaminophen overdose hepatotoxicity. Potential side effects include nausea, vomiting, increased secretions or bronchospasm. Nurses should observe the rights of medication administration and monitor the patient's respiratory status and sputum.

Uploaded by

Joshua Selwyn Salazar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOCX, PDF, TXT or read online on Scribd
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MECHANISM

DRUG DATA INDICATIONS / CONTRAINDICATION NURSING RESPONSIBILITIES


OF ACTION / SIDE EFFECTS
Generic name: Mechanism of action: Indication: Observe the 10 rights of medication:
 N-acetylcysteine
Before:
Splits linkage of mucoproteins, reducing Bronchodilators should be
Brand name: viscosity of pulmonary secretions.  Assess pretreatment respirations for rate, depth,
given 10–15 min before acetylcysteine.
 Mucomyst rhythm.
Therapeutic Effect: Facilitates removal of
pulmonary secretions by coughing, postural During:
Classification: drainage, mechanical means. Protects against Contraindication:
 Mucolytic Agent, acetaminophen overdose induced hepatotoxicity  If bronchospasm occurs, discontinue treatment,
Mucolytics  Large doses may produce severe notify physician; bronchodilator may be added to
nausea/vomiting. (Less than 2%): Serious therapy. Monitor rate, depth, rhythm, type of
Patient’s Dose: Side effects: anaphylactoid reactions including cough, respiration (abdominal, thoracic).
 10% (100 mg/ml) wheezing, stridor, respiratory distress,
Route:  Stickiness on face, transient unpleasant bronchospasm, hypotension, and death After:
 Inhalation, odor. have been known to occur with IV  document and record.
nebulization (NAS)  Occasional: Inhalation: Increased administration.  Check sputum for color, consistency, amount.
bronchial secretions, throat irritation,
Frequency: nausea, vomiting, rhinorrhea.
 q6h  Rare: Inhalation: Rash.

Adverse effects:

 Large doses may produce severe nausea/


 vomiting.
 (Less than 2%): Serious anaphylactoid
reactions including cough, wheezing,
stridor, respiratory distress,
bronchospasm, hypotension, and death
MECHANISM
DRUG DATA INDICATIONS / CONTRAINDICATION NURSING RESPONSIBILITIES
OF ACTION / SIDE EFFECTS
Generic name: Mechanism of action: Indication: Observe 10 rights of medication
 dornase alfa
Before:
Brand name: Recombinant human DNase 1,  Dornase alfa is indicated for daily
 Pulmozyme digests neutrophil DNA administration in conjunction with  Mucolytic: Assess pretreatment respirations for rate, depth,
deposited in the pulmonary standard therapies for the management of rhythm.
Classification: mucosa thereby reducing cystic fibrosis (CF) patients to improve
pulmonary function. During:
 Enzymes, Mucolytic mucosal viscoelasticity
Agent  Do not use any other inhaled medicines in the nebulizer at the
Side effects: Contraindication: same time. Keep all other inhaled medication systems completely
Patient’s Dose:
separate from Pulmozyme.
 1mg/mL (2.5mL)  Urticaria, mild to  Hypersensitivity to dornase alfa or Chinese
Route: moderate, and mild skin hamster ovary cell products  Do not use a mask. Use the mouthpiece provided with each
 Inhalation, rash nebulizer kit.
nebulization
After:

Frequency:  document and record.


 q6h

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