DRUG CLASSIFICATION ACTION OF DRUG INDICATION AND SIDE EFFECT NURSING CONSIDERATION

CONTRAINDICATION
Generic name: Gentamycin Anti-infectives Inhibits protein synthesis in Indication: Side Effects EENT: ototoxicity BEFORE:
bacteria at level of 30S Specific Indication (vestibular and cochlear) - Assess child for infection
Brand name: (Garamycin) ribosome, bactericidal Treatment of serious gram (vital signs, wound appearance,
action. negative bacillary infections GU: nephrotoxicity. sputum, urine, stool, WBC) at
Ordered Dose: 90 mg IV q and infections caused by beginning of and throughout
8 hr staphylococci when F and E: hypomagnesemia. therapy.
penicillins or other less toxic - Obtain specimens for culture
drugs are contraindicated MS: muscle paralysis (high and sensitivity before initiating
parenteral doses). Misc: therapy. First dose may be
Contraindication: hypersensitivity reactions. given before receiving results.
>low amount of - Monitor intake and output and
calcium in the blood. daily weight to assess hydration
status and renal function.
>dehydration.
- Assess child for signs of
a type of movement superinfection (fever, upper
disorder called respiratory infection, vaginal
parkinsonism. itching or discharge, increasing
>myasthenia gravis. malaise, diarrhea).
a skeletal muscle respiratory infection, vaginal
disorder. itching or discharge, increasing
>ringing in the ears. malaise, diarrhea)
disorder of nerve DURING:
that controls hearing and - Advise child of the
balance. importance of drinking plenty
>decreased kidney of liquids.
function. - Missed doses should be taken
as soon as possible if not
almost time for next dose; do
not double doses.

AFTER:
- Instruct child's mother to take
as directed for full course of
therapy
- Mother should assess skin and
inform health care professional
if skin irritation develops or
infection worsens.
Generic name: Morphine Oploid agonist analgesic Mechanism of Action Indication: Flushing, tachycardia, bradycardia, -Dilute administer slowly IV to
Sulfate Principal opium alkaloid -Relief moderate to severe arrythmia, palpitations, hypertension minimize adverse effects.
acts as agonist at specific acute and chronic pain. -Avoid alcohol, anti
Brand name: Astramorph, oploid receptors in the CNS -Analgesics adjust during histamines, sedatives,
Daramorph, Epimorph to produce analgesia, anesthesia. tranquilizers during
euphoria, sedation -Intaspinal use with medication.
Ordered Dose: 2 mg 1-2 microfusion devices for the -Report severe nausea,
hrsprnpain relief of intractable pain. vomiting, shortness of breath.

Contraindicated:
Contraindicated to patients
with hypersensitivity to
opoids. Use cautiously with
acute asthma, corpulmonale,
hypoxia, hypercapnia

Brand name: Promethazine Pharmacologic Class: Selectively blocks the H Indication: CNS: Dizziness, drowsiness, Before
HCI Phenothiazine receptors, diminishing the - Prevention and treatment poor coordination, confusion, -Observe 15 rights in drug
effects of histamine on cells of nausea and vomiting restlessness, excitation, seizures, administration.
Generic name: Phenergan Therapeutic Class: of the upper respiratory associated with labyrinthitis tremors headache, blurred vision, - Assess for hypersensitivity
Antiemetic Antihistamine, tract and eyes and - Prevention of motion diplopia, vertigo, tinnitus and other contraindications.
Ordered Dose: 125 mg q 4- Sedative, Hypnotic decreasing the sneezing, sickness - Reduce dosage for patients
6 hrsprnnausea mucus production, itching - Short-term management of CV: Hypotension, with hepatic impairment.
Pregnancy Risk Factor: с and tearing that accompany insomnia palpitations bradycardia, tachycardia. - Reduce dosage of
allergic reactions in - Symptomatic relief of extrasystoles barbiturates given concurrently
sensitized people exposed perennial and seasonal with promethazine by at least a
to antigens; blocks allergic rhinitis, allergic Dermatologic: Urticaria, half.
cholinergic receptors in the conjunctivitis. rash, photosensitivity, chills - Arrange for dosage reduction
vomiting centre that are uncomplicated urticaria and of opioid analgesics given
believed to mediate the angioedema GI: Epigastric distress concomitantly by one fourth to
nausea and vomiting caused - Amelioration of allergic nausea, vomiting, diarrhea, one-half.
by gastric irritation, by reactions to blood or plasma constipation
input from the vestibular - Dermatographism During
apparatus, and by input adjunctive therapy in GU: Urinary frequency - Do not give tablets or rectal
from the chemoreceptor anaphylactic reactions dysuria, urinary retention, decreased suppositories to children
trigger zone; depresses the - Preoperative postoperative, libido, impotence younger than 2 yr.
RAS, including the parts of or obstetric sedation - Give IM injections deep into
the brain involved with - Adjunct to analgesics to Hematologic: Hemolytic muscle
wakefulness. control postoperative pain anemia, hypoplastic anemia, - Do not administer
 - Adjunctive IV therapy with thrombocytopenia.leukopenia, subcutaneously, tissue necrosis
reduced amounts of agranulocytosis, pancytopenia may occur.
meperidine or other opioid - Do not administer
analgesics in special surgical intrarterially: arteriospasm and
conditions gangrene of the limb may result
- Instruct to take drug exactly
Contraindications: as prescribed.
-Hypersensitivity to
antihistamines or After
phenothiazines - Instruct to avoid alcohol.
- Comatose patients - Severe - Instruct to avoid driving or
CNS depression engaging in other dangerous
- B * o * r marrow activities of dizziness,
depression - Vomiting of drowsiness or vision changes
unknown cause - occur.
Concomitant therapy with - Educate about avoiding
MAOI's prolonged exposure to the sun,
or using of sunscreen or
covering garments.
- Maintain fluid intake, use
precautions against heatstroke
in hot weather. Report sore
throat, fever, unusual bleeding
or bruising, rash, fever,
weakness, tremors, impaired
vision, dark urine, pale stools,
yellowing of the skin or eyes.

Generic Name: Ceftriaxone Bactericidal; inhibits Indication: CNS: headache, dizziness, lethargy
sodium Pharmacologic: 3 degrees synthesis of bacterial cell > Lower respiratory Before:
generation cephalosporin wall, causing cell death. infections caused GI: nausea, vomiting, diarrhea, > check doctor's order
Brand Name: Rocephin bystreptococcus pneumoniae anorexia, pseudomembranou s colitis > perform handwashing
Therapeutic: Antibiotic > acute bacterial otitis media > introduce drug to the patient
Ordered Dose: 900 mg > UTIS caused by E. coli GU: nephrotoxicity and educate her about its
IVqdaily Pregnancy Category Risk: > intra-abdominal infections purpose and importance
B > PID caused by Gonorrhea Hematologic: bone marrow > assess for hepatic and renal
N. gonorrhoeae depression - decreased WBC impairment, lactation,
> skin and skin structure count,decreased platelets, decreased pregnancy
infections Hct > assess skin status, LFTs,
> septicaemia renal function tests, culture of
> bone and joint infections Hypersensitivity: ranging from rash affected area, sensitivity tests
> meningitis to fever to anaphylaxis
 > Lyme disease During:
> administer the right drug at
Contraindications: the right dose
Contraindicated with allergy > check the patency of the IV
to cephalosporin or site and IV line
penecillins > have vitamin K ready in case
hypoprothrombinemia occurs
> do not mix ceftriaxone with
any other antimicrobial drug
> discontinue if
hypersensitivity reaction occurs

After:
> educate patient to avoid
alcohol while taking this drug
and for 3 days after because
severe reactions often occur
> patients with severe renal
impairment and in patients with
renal and hepatic impairment
> report severe diarrhea,
difficulty breathing, unusual
tiredness or fatigue, pain at
injection site
> document and record.
monitor ceftriaxone blood
levels in

Generic Name: antipyretics, nonopioid Mechanism of Action Indication: Side Effects Hema: hemolytic BEFORE
Acetaminophen analgesics Inhibits the synthesis of Specific Indication Mild anemia, neutropenia, leukopenia, - Advise parents or caregivers
prostaglandins that may pain Fever pancytopenia Hepa: jaundice to check concentrations of
serve as mediators of pain Metabolic: hypoG GI: HEPATIC liquid preparations. Errors have
Brand Name: and fever primarily in the Contraindication: FAILURE, HEPATOTOXICITY resulted in serious liver damage
Panadol, Tylenol. CNS caloric (overdose) GU: renal failure (high - Assess fever; note presence of
undernutrition. doses/chronic use) Derm: rash, associated signs (diaphoresis,
Ordered Dose: 80mg poq 4 urticaria tachycardia, and malaise).
acute liver failure.
hrsprn
liver problems. DURING:
severe renal - Adults should not take
impairment. acetaminophen longer than 10
a condition where days and children not longer
the body is unable to than 5 days unless directed by
maintain adequate blood health care professional
flow called shock. - Advise mother or caregiver
acetaminophen to take medication exactly as
overdose. directed and not to take more
than the recommended amount.
acute inflammation
of the liver due to hepatitis
AFTER
C virus.
- Advise patient to consult
health care professional if
discomfort or fever is not
relieved by routine doses of
this drug or if fever is greater
than 39.5 degrees * C * (103
degrees * F) or lasts longer
than 3 days