St. Augustine’s School of Iba Inc.
Iba, Zambales
                                   SY 2020-2021
                   GENERAL BIOLOGY 1
                                 MODULE 1
         THE WORLD OF THE CELL
NAME: ________________________________________________________________________
GRADE AND SECTION: ____________________________________________________________
             Prepared by: Clarinda A. Bautista
            CURRICULUM CONNECTION
                       LIFE PERFORMANCE OUTCOME
LPO 1 : Mindful, Self-directed Learners and Role Models
LPO 4 : Conscientious, Adept Performers and Achievers
                             PROGRAM OUTCOME
        All St. Augustine’s School, Inc. graduates can accurately apply and
integrate sound concepts, skills, processes, technologies, and information from
the major scientific disciplines to develop and implement workable strategies
that have a direct bearing on their daily lives and decisions.
                    ESSENTIAL PERFORMANCE OUTCOME
EPO4 : Describe and explain the new Scientific abilities they have developed as
the result of self-initiated learning experiences and projects
EPO3 : Explain the factors that generally affect their decisions and actions, and
assess the consequences they produce.
EPO6 : Consistently seek feedback from informed, credible individuals on the
accuracy, clarity, authenticity, and scientific techniques and practice revising
and restating them until they are well received.
EPO10 : Openly demonstrate their basic and advanced Science Process skills as
experienced individuals and improve them according to the feedback they
receive.
                            CONTENT STANDARDS
   The learners demonstrate understanding of cell theory, cell structure and
functions, prokaryotic vs. eukaryotic cells, cell types and cell modifications.
                         PERFORMANCE STANDARDS
        The learners should be able to construct a 3D model of a plant/animal/
bacterial cell using recyclable materials.
                         APPLICATION COMMITMENT
        Initiate and sustain efforts that draw attention to environmental issues
 and propose workable measures to reduce and eventually eliminate them.
                         UNIT 1 : THE WORLD OF THE CELL
                                                                            Learning competencies
                                                                           At the end of the lesson, you
                                                                           should be able to:
                                                                           1. Explain the postulate of the cell
                                                                           theory.
                                                                           2. Describe the structure and
                                                                           function of major and subcellular
                                                                           organelles.
                                                                           3. Distinguish prokaryotic from
                                                                           eukaryotic cells according to their
                                                                           distinctive features
Figure 1. An electron micrograph scans of gram-positive Mycobacterium
                                                                           4. Classify different cell types and
tuberculosis bacteria that cause tuberculosis.
                                                                           specify the functions of each.
                                                                           5. Describe some cell
                Introduction to Cell Biology                               modifications that lead to
                                                                           adaptation to carry out specialized
       There are more than 350 000 species of known plants and             function
more is to be discovered and name. Their fascinating morphology
and their ability to regulate and maintain homeostasis are studied by
botanist.
         What do paramecium and whales have in common? Why is
the shape of a neuron different from that of a red blood cell even if
it carries the same genetic code? What do cancerous cells mean?
       Understanding the basics of cell structure will lead us to the
answer to these questions. As a student, you will be able to
understand the basic structure among all organisms, that is, the cell.     Figure 2: Plant cell’s chloroplast.
                                          Cellular Structure
                                                 Your body has many kinds of cells each specialized for a
                                         specific purpose. Human body is like a house made from a variety
                                         of building materials constructed from many cell types. For
                                         example, an epithelial cell protects the surface of the body and
                                         covers the organ and body cavities within. Bone cells produce
                                         substances to support and protect the body. Cells of the immune
                                         system fight invading bacteria. Blood and blood cells carry nutrients
                                         and oxygen throughout the body while removing carbon dioxide.
 Figure 3: Animal’s red blood cells.
       Each of these cell types plays a vital role during the growth, development and day-to-day
maintenance of the body. In spite of their enormous variety, however, cells from all organism even ones as
diverse as bacterium, onion and human share certain fundamental characteristics.
                         The Cell Theory
       Prior to the invention of the very first microscope, everything
that could not be seen by the naked eye was unexplained. In 1665,
Robert Hooke was able to observe in a piece of cork specimen structure
which appear as tiny compartments similar to small rooms that are fitted
to each other ( Figure 4). Hook coined the word “cell” to describe these
            Activity 1: The Discovery and Binding Mechanisms of Life
Directions: Carefully read, analyze and answer the activity below. Watch a video or make research about
the “Cell Theory” which tells about the story of the discovery of cell. Identify the scientist by their work
statement and explain how they discover it. Choose from the box which scientist gave the following. Write
your answer in the table.
Rudolf Virchow        Anton Van Leeuwenhoek                              Matthias Schleiden
                Theodor Schwann SCIENTIST
         STATEMENT                                          Robert Hooke EXPLAINATION
Thousands of tiny empty chambers           Cell Organelles
  in cork are called cell (1665)
Tiny living organisms are observed
              (1676)
  All plants are made up of cells
               (1838)
 All animals are made up of cells
              (1839)
 All cells come from pre-existing
            cells (1858)
REFLECTION:
In your own words, why is the discovery of cell so important?
______________________________________________________________________________________
        All living organelles are composed of one or many cells. The cell is the building block of life,
______________________________________________________________________________________
which is able to control and execute several functions in all types of organisms. The cell is generally
______________________________________________________________________________________
microscopic, but its size varies from one organism to another and also from the parts of the organism itself.
______________________________________________________________________________________
Cell structures can only be observed under high magnification electron microscope and are separated
______________________________________________________________________________________
internally into numerous membranous compartment called organelles (little organs).
                               Activity 2: Organelles Nicknames
Directions: Complete the table. Write the name of each organelle in the blanks. In the second column,
indicate
   Figuresit 5is and
                 found  in animal cell,Plant
                     6: Respectively,   plantand
                                              cellanimal
                                                   or both.organelles
                                                             Create a nickname  for each organelle that is connected
                                                                      3D structure.
to its function. Write its function and comparison in the last column and answer the guide questions below.
                  Animal/
  Organelle        plant/       Nickname                  Function                     In the same way…
                    both
                                                                               The security guard controls
   Plasma                        Security      Cell membrane controls what
                    Both                                                      that comes in and goes out of
  Membrane                        Guard        comes into and out of the cell
                                                                                   the school premises.
   Nucleus
  Cytoplasm
  Ribosomes
 Endoplasmic
  Reticulum
   Golgi
  Apparatus
  Chloroplast
 Mitochondria
 Cytoskeleton
     Cilia
   Flagella
Guide Questions:
1. Organelles work together to sustain the overall function of the cell and maintain homeostasis. Predict
what would happen if one of the organelles was removed. How would that affect the survival and
efficiency of the cell?
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
2. Among the cellular structures described in the activity, which organelles do you think is the most
important?
______________________________________________________________________________________
______________________________________________________________________________________
______________________________________________________________________________________
             Cell Types
       Every living organism falls into
one of two groups: eukaryotes or
prokaryotes.     Cellular    structure
determines which group an organism
belongs to.
        The      difference     between
prokaryotic and eukaryotic organisms is
said to be the most important distinction
among the groups of living things.
Deriving from the name itself, “eu”
means “true” while “karyon” means
“nucleus.”
       The main difference is that the
eukaryotic cells’ chromosomes are
enclosed inside the nucleus while the
prokaryotes’ DNA (“pro” means
“before”) is found in region called
“nucleoid” that has no membrane.
However, both types of cells possess
cytoplasm. In prokaryotes, aside from
not having a true nucleus, a semi –rigid
cell wall is present and membrane-
bound organelles with specialized
functions are absent.
Figure 7: This figure shows the generalized structure of a prokaryotic cell. All prokaryotes have chromosomal
          DNA localized in a nucleoid, ribosomes, a cell membrane, and a cell wall.
Figure 8: Examples of microbial cell shape.
           All prokaryotic organisms are unicellular (single-celled) which include the members of Kingdom
  Eubacteria and Archaebacteria. They are much simpler in unicellular structure (Figure 7) and may occur
  singly,
Figure  9: in
           Thepairs, chains,
                figure showsclusters,   aggregates
                               relative sizes        or colonies.
                                              of microbes         Prokaryoticscale
                                                           on a logarithmic    organisms    are each
                                                                                   (recall that extremely
                                                                                                     unit ofmicroscopic
                                                                                                             increase in
  ranging from
logarithmic   scale1-10  micrometers
                    represents  a 10-foldinincrease
                                            diameters   compared
                                                    in quantity    to measured).
                                                                being eukaryotic cells that are bigger with 10-100
  micrometer in diameter. Some species are rod-shaped (bacilli), spherical (cocci), spiral, etc.
          All multicellular organisms including humans, which are composed of complex or many cells, are
  examples of eukaryotic cells. Kingdom Protista, Fungi, Plantae and Animalia are the members of eukaryotes’
  cellular structures perform variety of functions. Plasma membrane and cell wall are found in both cell types;
  however, their composition and structure are highly dissimilar. Different eukaryotic organisms have varying
  features in terms of the composition, structure, and function of the cell organelles. For instance, fungi cell is
  different to plant cell in many aspects.
                                       Activity 3: Present or Absent?
    Directions: Complete the table. Write in the table “Present” if the organelle is present to prokaryotic or
    eukaryotic and if not write “absent” and answer the guide questions below.
                  Organelle
                                                     Prokaryotes                         Eukaryotes
             Plasma Membrane
                   Nucleus
                  Cytoplasm
                 Ribosomes
           Endoplasmic Reticulum
              Golgi Apparatus
                 Chloroplast
                Mitochondria
                Cytoskeleton
                  Cell Wall
           Vesicles and Vacuoles
   Guide Questions:
   1. Are all prokaryotes unicellular? Can they be multicellular? Explain.
   ______________________________________________________________________________________
   ______________________________________________________________________________________
   ______________________________________________________________________________________
   2. What is the significant of compartmentalization of eukaryotic cells?
   ______________________________________________________________________________________
   ______________________________________________________________________________________
   ______________________________________________________________________________________
                   Let’s Review
   •   Cells are the smallest functional unit that makes up all living things.
   •   The cell membrane is a dynamic barrier that is semi-permeable and fluid, composed of a
       phospholipid bilayer and proteins.
   •   The endomembrane system is composed of the endoplasmic reticulum, Golgi bodies, lysosomes;
       transport vesicle, vacuoles and other membrane bound components.
   •   Unicellular organisms have different cell structures than multicellular organism; plant cells have
       different structures from animal cells so as the prokaryotic and eukaryotic cells.
        Congratulations, you had just finished your module 1! After studying our lesson, kindly write the
things you learned, found interesting and question as your learning summaries
    Congratulations, you have finished your lessons in module 1! After studying our lesson, kindly
    write the things you learned, found interesting and question as your learning summaries.
    My Reflection:
    1. What points do I learned while doing the activities? ________________________________________
    ____________________________________________________________________________________
    2. What difficulties have I encountered in doing the activities? _________________________________
    ___________________________________________________________________________________
   REFERENCES
  Book References:
  Dequillo, Ma. Rea, M.,et al, 2017, General Biology 1, Rex Book Store, Inc.
  M. Ayassar, et al, 2017, General Biology 1, Vibal Publishimg
  Digital/Internet References:
  Robert Hooke’s drawing of cork
  https://ucmp.berkeley.edu/history/hooke.html
  Animal cell organelles 3D
  https://stock.adobe.com/ph/images/animal-cell-3d-rendering-isolated-on-white-with-the-organelles-labeled/250912083
  Plant cell organelles 3D
  https://www.pinterest.ph/pin/363173157426532105/
  Picture: Mycobacterium tuberculosis
  https://www.google.com/url?sa=i&url=http%3A%2F%2Ftextbookofbacteriology.net%2Ftuberculosis.html&psig=AOv
  Vaw3bHhX-
  fXqhvxIVCERYxbxI&ust=1599153273034000&source=images&cd=vfe&ved=0CAIQjRxqFwoTCLDWzKn8yusCFQ
  AAAAAdAAAAABAD
  Picture: Plant cell chloroplast
  https://www.google.com/url?sa=i&url=https%3A%2F%2Fwww.pinterest.com%2Fpin%2F540150549037636494%2F&
  psig=AOvVaw1gyIlc4ZZSvK8F6AYvYgfc&ust=1599153533484000&source=images&cd=vfe&ved=0CAIQjRxqFwo
  TCNjHmKX9yusCFQAAAAAdAAAAABAD
  Microbial cell shape
  https://www.google.com/url?sa=i&url=http%3A%2F%2Fwww.miraclesregenerative.com%2Fanti-
  bacteria%2F&psig=AOvVaw0DPvdksPIoYCmqqfPtE4MW&ust=1599155804279000&source=images&cd=vfe&ved=
  0CAIQjRxqFwoTCNCdmuCFy-sCFQAAAAAdAAAAABAI