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Drug Study: Valerie V. Villanueva BN3-C

Dopamine hydrochloride (Dopamax) is an inotropic agent used to treat shock, heart failure, and bradycardia. It works by activating dopamine, beta-1 adrenergic, and alpha adrenergic receptors, increasing cardiac output at low doses, enhancing contractility at moderate doses, and causing vasoconstriction at high doses. Potential adverse effects include hypotension, hypertension, tachycardia, anginal pain, and tissue necrosis if extravasated. Nurses are responsible for monitoring patients on dopamine infusions and correcting any hypovolemia.

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0% found this document useful (0 votes)
252 views2 pages

Drug Study: Valerie V. Villanueva BN3-C

Dopamine hydrochloride (Dopamax) is an inotropic agent used to treat shock, heart failure, and bradycardia. It works by activating dopamine, beta-1 adrenergic, and alpha adrenergic receptors, increasing cardiac output at low doses, enhancing contractility at moderate doses, and causing vasoconstriction at high doses. Potential adverse effects include hypotension, hypertension, tachycardia, anginal pain, and tissue necrosis if extravasated. Nurses are responsible for monitoring patients on dopamine infusions and correcting any hypovolemia.

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Drug Study

Dopamine HCl
Valerie V. Villanueva BN3-C
Dosage,
Name of Drug Frequency, Mechanism of Action Indication Contraindication Adverse Effect Nursing Responsibility
Route
Generic Name: Dosage: Low dose (<3 mcg/kg/min): Shock: Moderate doses  Tachy-  Hypotension,  Correct hypovolemia with
Dopamine 400mg/500 activates dopaminergic enhance contractility dysrhythmias hypertension, fluid resuscitation before
hydrochloride ml receptors in kidneys producing increasing cardiac output;  Ventricular tachycardia initiating dopamine
renal artery dilation. High doses produce fibrillation  Anginal pain, infusion.
Brand Name: Frequency: vasoconstriction to  Pheochromocyt ectopic beats,  Monitor blood pressure,
Dopamax 5 cc/hr Mid dose (3 – 10 mcg/kg/min): enhance blood pressure. oma vasoconstriction pulse, and peripheral pulses
primarily  Safety during (cold every 15 minutes.
Classification: Route: activates β1 adrenergic Heart Failure: At moderate pregnancy, extremities)  Monitor hourly urine
Inotropic Agents IVTT receptors in heart increasing doses, dopamine enhances lactation or with  Nausea, output.
heart rate (positive contractility. Higher doses children not vomiting,  Cardiac monitor should
chronotropic agent), exacerbate heart failure by established. headache be used on patients
contractility (positive inotropic increasing afterload and  Tissue necrosis receiving dopamine
agent) producing additional and sloughing if infusion.
workload on the heart. extravasation  Weigh patient daily to
High dose (10 – 20 occurs determine accurate infusion
mcg/kg/min): activates α- Bradycardia: Dopamine is dose.
adrenergic receptorsproducing a 2nd line drug after  Calculate infusion drips
vasoconstriction atropine for bradycardias. and doses carefully.
(increasing systemic vascular Double-check calculations
resistance or left ventricular with another nurse or
afterload) pharmacist.
 IV site should not be used
for any other infusions or IV
therapies.

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