Response Sheet 02/05/22, 8:48 PM

Print ResponseSheet

NTA - GPAT 2022 Examination

(Candidate Response Sheet)
Roll Number HR03000126
Name of the
VINAY KUMAR
Candidate
Examination
NTA GPAT APRIL 2022
Name
Exam Date & Time 09-04-2022 09:00:00

Subject : Pharmaceutical Chemistry SET 02

Question ID:- 28

Ethylketazocine is a 6,7-benzomorphan derivative with ________

receptor selectivity.

Options:-
.Mu–opioid , Option ID :- 109,
. Delta–opioid , Option ID :- 110,
. Kappa–opioid , Option ID :- 111,
. NOP , Option ID :- 112,
Answer Given:- Kappa–opioid , Option ID : -111

Question ID:- 22

The major product formed in the above-given Knorr synthesis is:

Options:-

. , Option ID :- 85,

. , Option ID :- 86,

. , Option ID :- 87,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 1 of 48
Response Sheet 02/05/22, 8:48 PM

. , Option ID :- 88,

Answer Given:- , Option ID : -86

Question ID:- 10

Given below are the two statements

Statement I: Glucose-6-phosphate can be formed from glucose, but not

from

glycogen.

Statement II: Glucose-1-phosphate may be hydrolyzed to yield free

glucose in

liver.

Choose the most appropriate answer from the options given below:

Options:-
.Both Statement I and Statement II are correct , Option ID :- 37,
. Both Statement I and Statement II are incorrect , Option ID :- 38,
. Statement I is correct but Statement II is incorrect , Option ID :- 39,
. Statement I is incorrect but Statement II is correct , Option ID :- 40,
Answer Given:- Both Statement I and Statement II are correct , Option
ID : -37

Question ID:- 11

Optically active mandelic acid can be synthesized from benzaldehyde in

the presence of the enzyme:

Options:-
.Invertin , Option ID :- 41,
. Myrosin , Option ID :- 42,
. Emulsin , Option ID :- 43,
. Zymase , Option ID :- 44,
Answer Given:- Myrosin , Option ID : -42

Question ID:- 12

Isobutane upon bromination under the influence of ultraviolet light at

127 °C affords the following major product:

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 2 of 48
Response Sheet 02/05/22, 8:48 PM

Options:-
.N-Butyl bromide , Option ID :- 45,
. Isobutyl bromide , Option ID :- 46,
. sec-Butyl bromide , Option ID :- 47,
. ter-Butyl bromide , Option ID :- 48,
Answer Given:- Isobutyl bromide , Option ID : -46

Question ID:- 32

Match List I with List II, and

List I List II

Volumetric Solution Primary Standard

A. 0.1 M Iodine I. Potassium iodate

B. 0.1M Sodium
II. Potassium bromate
thiosulphate

C. 0.1M Sodium III. Potassium hydrogen

hydroxide phthalate

D. 0.1M Perchloric
IV. Arsenic trioxide
acid

V. Potassium hydrogen
phthalate

Choose the correct answer from the options given below:

Options:-
.A - IV, B - II, C - III, D - V , Option ID :- 125,
. A - IV, B - II, C - III, D - I , Option ID :- 126,
. A - I, B - IV, C - II, D - III , Option ID :- 127,
. A - III, B - II, C - IV, D - I , Option ID :- 128,
Answer Given:- A - IV, B - II, C - III, D - I , Option ID : -126

Question ID:- 26

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 3 of 48
Response Sheet 02/05/22, 8:48 PM

Identify which statement among the following is true in case of E2 and

SN2:

Options:-
.Secondary substitution undergoes slow elimination and fast
substitution , Option ID :- 101,
. Primary substitution undergoes slow elimination and fast substitution ,
Option ID :- 102,
. Tertiary substitution undergoes slow elimination and fast substitution ,
Option ID :- 103,
. Primary substitution does not undergo elimination and substitution
reactions , Option ID :- 104,
Answer Given:- Secondary substitution undergoes slow elimination and
fast substitution , Option ID : -101

Question ID:- 33

Potential at the equivalence point for a redox reaction

aOX1 + bRED2 bOX2 + aRED1

is given by the equation:

Options:-
.E = (bE10 + aE20)/(a+b) , Option ID :- 129,
. E = E0 + (0.0592/n) X log Q , Option ID :- 130,
. E = E0 + (0.0592/n) X log (Red/Ox) , Option ID :- 131,
. E = E10 + E20/2 , Option ID :- 132,
Answer Given:- E = E0 + (0.0592/n) X log (Red/Ox) , Option ID : -131

Question ID:- 2

Cottrell’s method is used for the measurement of:

Options:-
.Depression of freezing-point , Option ID :- 5,
. Elevation of boiling-point , Option ID :- 6,
. Lowering of vapour pressure , Option ID :- 7,
. Osmotic pressure , Option ID :- 8,
Answer Given:- Lowering of vapour pressure , Option ID : -7

Question ID:- 21

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 4 of 48
Response Sheet 02/05/22, 8:48 PM

The set of specific reagents used in the above-mentioned synthesis of m-

(n-Butyl)toluene from n-propyl m-tolyl ketone is:

Options:-
.Zn(Hg), HCl , Option ID :- 81,
. NaBH4, CH3OH , Option ID :- 82,
. NH2NH2, NaOH , Option ID :- 83,
. SnCl2, CH3OH , Option ID :- 84,
Answer Given:- SnCl2, CH3OH , Option ID : -84

Question ID:- 20

The major product formed in the above acid-catalyzed reaction is:

Options:-

. , Option ID :- 77,

. , Option ID :- 78,

. , Option ID :- 79,

. , Option ID :- 80,

Answer Given:- , Option ID : -80

Question ID:- 6

Heme is ________ .

Options:-

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 5 of 48
Response Sheet 02/05/22, 8:48 PM

.iron containing tetrapyrrole , Option ID :- 21,

. iron containing polypeptide , Option ID :- 22,
. copper or magnesium containing tetrapyrrole , Option ID :- 23,
. iron containing imidazole , Option ID :- 24,
Answer Given:- iron containing imidazole , Option ID : -24

Question ID:- 15

In the determination of configuration of glucose, Fischer subjected (-)

arabinose to Ruff’s degradation. The four-carbon sugar obtained by the
degradation process was:

Options:-
.(-) Threose , Option ID :- 57,
. (+) Threose , Option ID :- 58,
. (-) Erythrose , Option ID :- 59,
. (+) Erythrose , Option ID :- 60,
Answer Given:- (-) Threose , Option ID : -57

Question ID:- 34

Benzene theoretically can have ____ number of possible fundamental

absorption bonds in the IR spectrum.

Options:-
.30 , Option ID :- 133,
. 15 , Option ID :- 134,
. 6 , Option ID :- 135,
. 0 , Option ID :- 136,
Answer Given:- 0 , Option ID : -136

Question ID:- 8

Citric acid cycle is the final pathway during the oxidation of _______ .

Options:-
.Carbohydrates , Option ID :- 29,
. Lipids , Option ID :- 30,
. Proteins , Option ID :- 31,
. All of these , Option ID :- 32,
Answer Given:- All of these , Option ID : -32

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 6 of 48
Response Sheet 02/05/22, 8:48 PM

Question ID:- 13

Identify the functional groups from the below mentioned options that lead to weakening of benzoic
acid:

A. –OH

B. –Cl

C. –NH2

D. –NO2

Options:-
.A and B , Option ID :- 49,
. A and C , Option ID :- 50,
. B and C , Option ID :- 51,
. A and D , Option ID :- 52,
Answer Given:- B and C , Option ID : -51

Question ID:- 38

According to the n + 1 rule, what would be the multiplicities of the

signals in the proton NMR spectrum of 1,1-dibromoethane?

Options:-
.Triplet and doublet , Option ID :- 149,
. Quartet and doublet , Option ID :- 150,
. Triplet and quartet , Option ID :- 151,
. Triplet and triplet , Option ID :- 152,
Answer Given:- Quartet and doublet , Option ID : -150

Question ID:- 30

When alkenes are epoxidised with optically active peracids, optically

active epoxides are formed. Under the same defined conditions,
epoxidation of E-but-2-ene by peroxycamphoric acid affords unequal
yields of enantiomeric epoxides. However, a similar epoxidation of Z-
but-2-ene can only afford ________ .

Options:-
.Z-epoxide , Option ID :- 117,
. Meso epoxide , Option ID :- 118,
. E-epoxide , Option ID :- 119,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 7 of 48
Response Sheet 02/05/22, 8:48 PM

. None of these , Option ID :- 120,

Answer Given:- None of these , Option ID : -120

Question ID:- 24

Identify the major product formed in the above reaction from the four
choices listed below:

Options:-
.(S)-(+)-2-methylbutanoic acid , Option ID :- 93,
. (S)-(-)-2-methylbutanoic acid , Option ID :- 94,
. (S)-(+)-2-methylbutanol , Option ID :- 95,
. (S)-(-)-2-methylbutanol , Option ID :- 96,
Answer Given:- (S)-(-)-2-methylbutanoic acid , Option ID : -94

Question ID:- 16

Insertion of a oxygen in a carbonyl compound to form an ester is known

as:

Options:-
.Baeyer Villiger oxidation , Option ID :- 61,
. Sharpless epoxidation , Option ID :- 62,
. Prevost oxidation , Option ID :- 63,
. Lossen rearrangement , Option ID :- 64,
Answer Given:- Baeyer Villiger oxidation , Option ID : -61

Question ID:- 18

Among the following organic compounds, the one that is non-aromatic is:

Options:-

. , Option ID :- 69,

. , Option ID :- 70,

. , Option ID :- 71,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 8 of 48
Response Sheet 02/05/22, 8:48 PM

. , Option ID :- 72,

Answer Given:- , Option ID : -69

Question ID:- 1

Match the symbols in the List I with the terms used in the List II of
conductance measurements, and

List I List II

Symbols Terms

A. Ω-1 I. Specific conductance

II. Electrical
B. Λ
conductance

C. k III. Specific resistance

IV. Equivalent
D. ρ
conductance

Choose the correct answer from the options given below:

Options:-
.A - III, B - I, C - IV, D - II , Option ID :- 1,
. A - II, B - IV, C - I, D - III , Option ID :- 2,
. A - IV, B - II, C - III, D - I , Option ID :- 3,
. A - I, B - III, C - II, D - IV , Option ID :- 4,
Answer Given:- A - III, B - I, C - IV, D - II , Option ID : -1

Question ID:- 35

Back-titration method is used for

A. Volatile substances

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?U…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 9 of 48
Response Sheet 02/05/22, 8:48 PM

B. Insoluble substances

C. Substances for which a quantitative reaction proceeds rapidly only in

the presence of excess of the

reagent

D. Substances that require heating with a volumetric reagent during the

determination, in which

decomposition or loss of the reactants would occur in the process

Choose the correct answer from the options given below:

Options:-
.A only , Option ID :- 137,
. A and C , Option ID :- 138,
. A, B and D , Option ID :- 139,
. A, B, C and D , Option ID :- 140,
Answer Given:- A only , Option ID : -137

Question ID:- 9

Which one of the following is NOT a phospholipid?

Options:-
.Sphingomyelin , Option ID :- 33,
. Lysolecithin , Option ID :- 34,
. Cardiolipin , Option ID :- 35,
. Galactosylceramide , Option ID :- 36,
Answer Given:- Galactosylceramide , Option ID : -36

Question ID:- 4

Boric acid with molecular weight 61.83 was partitioned between water
and amyl alcohol at 25 °C. The amount of boric acid was determined to
be 0.24 g in 250 ml of amyl alcohol and 0.32 g in 100 ml water. The
partition coefficient of boric acid between water and amyl alcohol, when
calculated at molar concentration for each of the solution, is:

Options:-
.1.33 , Option ID :- 13,
. 0.75 , Option ID :- 14,
. 0.30 , Option ID :- 15,
. 3.33 , Option ID :- 16,
Answer Given:- 3.33 , Option ID : -16

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 10 of 48
Response Sheet 02/05/22, 8:48 PM

Question ID:- 5

Drugs ‘A’, ‘B’ and ‘C’ follow zero order, first order and second order
degradation kinetics, respectively, but have the same rate constant.
Which of the following statement is true in this respect:

Options:-
.Drug ‘A’ will be the first to degrade by 50% , Option ID :- 17,
. Drug ‘B’ will be the first to degrade by 50% , Option ID :- 18,
. Drug ‘C’ will be the first to degrade by 50% , Option ID :- 19,
. Drugs ‘B’ and ‘C’ will degrade by 50% at the same time , Option ID :-
20,
Answer Given:- Drug ‘B’ will be the first to degrade by 50% , Option ID :
-18

Question ID:- 29

In the case of halogenation reaction of alkanes, abstract of primary

hydrogen yields a primary radical, and abstract of secondary hydrogen
yields a secondary radical.

The above example is of:

Options:-
.High reactivity and low selectivity , Option ID :- 113,
. Low reactivity and high selectivity , Option ID :- 114,
. High reactivity and high selectivity , Option ID :- 115,
. Low reactivity and low selectivity , Option ID :- 116,
Answer Given:- High reactivity and high selectivity , Option ID : -115

Question ID:- 19

The major product formed in the above reaction is:

Options:-

. , Option ID :- 73,

. , Option ID :- 74,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 11 of 48
Response Sheet 02/05/22, 8:48 PM

. , Option ID :- 75,

. , Option ID :- 76,

Answer Given:- , Option ID : -73

Question ID:- 23

Identify the product formed when 2-cholestene is treated with Br2:

Options:-
.5β, 6!!-dibromocholestane , Option ID :- 89,
. 2β, 3! -dibromocholestane , Option ID :- 90,
. 5α, 6β-dibromocholestane , Option ID :- 91,
. 5α, 6β-dibromo 3β-hydroxy cholestane , Option ID :- 92,
Answer Given:- 5α, 6β-dibromo 3β-hydroxy cholestane , Option ID : -92

Question ID:- 17

Controlled alkylation of a ketone via an enamine intermediate is named

as:

Options:-
.Mannich reaction , Option ID :- 65,
. Robinson annulation , Option ID :- 66,
. Stork reaction , Option ID :- 67,
. Bamford Stevens reaction , Option ID :- 68,
Answer Given:- Stork reaction , Option ID : -67

Question ID:- 3

Match the statements in List I with their correct answers in List II,
respectively, in respect to modified 1st law of thermodynamics, and

List I List II

A. Constant heat (q = 0) I.Isothermal

B. Reversible process at constant II.Isometric

temperature (dT = 0)

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 12 of 48
Response Sheet 02/05/22, 8:48 PM

C. Constant volume (dV = 0) III.Adiabatic

D. Constant pressure (dP = 0) IV. Isobar

Choose the correct answer from the options given below:

Options:-
.A - II, B - I, C - III, D - IV , Option ID :- 9,
. A - I, B - III, C - II, D - IV , Option ID :- 10,
. A - III, B - I, C - II, D - IV , Option ID :- 11,
. A - IV, B - I, C - II, D - III , Option ID :- 12,
Answer Given:- A - I, B - III, C - II, D - IV , Option ID : -10

Question ID:- 27

The above structure is of:

Options:-
.Norephedrine , Option ID :- 105,
. Pseudoephedrine , Option ID :- 106,
. Ephedrine , Option ID :- 107,
. Norpseudoephedrine , Option ID :- 108,
Answer Given:- Norpseudoephedrine , Option ID : -108

Question ID:- 37

According to Mohr method, the silver nitrate solution can be standardized

against primary- standard grade:

Options:-
.Sodium carbonate , Option ID :- 145,
. Sodium chloride , Option ID :- 146,
. Sodium hydrogen carbonate , Option ID :- 147,
. Sodium metabisulfite , Option ID :- 148,
https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 13 of 48
Response Sheet 02/05/22, 8:48 PM

Answer Given:- Sodium hydrogen carbonate , Option ID : -147

Question ID:- 36

The titration of a strong acid with a strong base is represented by plot

_____ .

Options:-

. , Option ID :- 141,

. , Option ID :- 142,

. , Option ID :- 143,

. , Option ID :- 144,

Answer Given:- , Option ID : -141

Question ID:- 31

When 100 mL of 0.1 M sodium hydroxide solution is added to 100 mL of

0.1 M acetic acid (Ka = 1.82 x 10-5), pH of the solution will be _____ .

Options:-
.8.3 , Option ID :- 121,
. 7.0 , Option ID :- 122,
. 3.8 , Option ID :- 123,
. 8.7 , Option ID :- 124,
Answer Given:- 8.3 , Option ID : -121

Question ID:- 25

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 14 of 48
Response Sheet 02/05/22, 8:48 PM

Identify the correct descending order of strength of nucleophilic solvents

from the below-given options:

Options:-
.Trifluroethyl alcohol; methanol; formic acid; acetic acid , Option ID :-
97,
. Formic acid; acetic acid; methanol; trifluroethyl alcohol , Option ID :-
98,
. Methanol; formic acid; acetic acid; trifluroethyl alcohol , Option ID :-
99,
. Methanol; acetic acid; formic acid; trifluoroethyl alcohol , Option ID :-
100,
Answer Given:- Methanol; acetic acid; formic acid; trifluoroethyl alcohol ,
Option ID : -100

Question ID:- 7

All enzymes accelerate the reaction rates by ______________ .

Options:-
.lowering activation energy barrier (ΔGf) for a reaction , Option ID :- 25,
. denaturing the substate , Option ID :- 26,
. increasing the temperature , Option ID :- 27,
. changing the pH , Option ID :- 28,
Answer Given:- lowering activation energy barrier (ΔGf) for a reaction ,
Option ID : -25

Question ID:- 14

Phenol upon treatment with bromine in the presence of carbondisulphide

at 0 °C yields:

Options:-
.4-Bromophenol , Option ID :- 53,
. 2-Bromophenol , Option ID :- 54,
. 2,4-Dibromophenol , Option ID :- 55,
. 2,4,6-Triibromophenol , Option ID :- 56,
Answer Given:- 2-Bromophenol , Option ID : -54
Subject : Pharmaceutics SET 02

Question ID:- 51

In thermoplastic materials, which are used as a container/packaging

material, additives like

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 15 of 48
Response Sheet 02/05/22, 8:48 PM

polyethylene and polypropylene are used as ___________

Options:-
.Plasticizer , Option ID :- 201,
. Stabilizers , Option ID :- 202,
. Surface treatment film , Option ID :- 203,
. Slip agent , Option ID :- 204,
Answer Given:- Plasticizer , Option ID : -201

Question ID:- 53

Which one of the following manufacturing facility may not be required for
oral solid dosage

form?

Options:-
.Material Handling , Option ID :- 209,
. Chemical weighing , Option ID :- 210,
. Blending , Option ID :- 211,
. Aspectic filling , Option ID :- 212,
Answer Given:- Blending , Option ID : -211

Question ID:- 70

Prescription price consists of

Options:-
.Cost of ingredients only , Option ID :- 277,
. Cost of professional fee only , Option ID :- 278,
. Cost of ingredients and cost of dispensing only , Option ID :- 279,
. Cost of ingredients and professional fee only , Option ID :- 280,
Answer Given:- Cost of ingredients and professional fee only , Option ID :
-280

Question ID:- 58

Which one of the following statement holds true for Passive Diffusion?

Options:-

.Greater the area and greater the thickness, faster is the diffusion ,
Option ID :- 229,
. Rate of drug transfer is directly proportional to the concentration
https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 16 of 48
Response Sheet 02/05/22, 8:48 PM

gradient between GI fluids and the blood compartment , Option ID :-

230,

. Rate of transfer of ionised drug species is 3-4 times the rate for
unionised drug species , Option ID :- 231,
. Greater the membrane/water partition coefficient of drug, slower is
the absorption , Option ID :- 232,
Answer Given:- Greater the membrane/water partition coefficient of
drug, slower is the absorption , Option ID : -232

Question ID:- 71

Hospital Formulary contains information on the following parameters

except

Options:-
.Composition , Option ID :- 281,
. Indication , Option ID :- 282,
. Pricing , Option ID :- 283,
. Dosage and administration , Option ID :- 284,
Answer Given:- Composition , Option ID : -281

Question ID:- 73

Which of the following statements are true about Prions

A. Prion is a type of infectious protein

B. Prions contain single stranded RNA

C. Creutzfeldt-Jakob disease (CJD) is not caused by Prion

D. Prions are even more difficult to destroy than bacterial spores

Choose the correct answer from the options given below:

Options:-
.A, B and D only , Option ID :- 289,
. A only , Option ID :- 290,
. A and D only , Option ID :- 291,
. A, C and D only , Option ID :- 292,
Answer Given:- A, B and D only , Option ID : -289

Question ID:- 66

Match List I with List II

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 17 of 48
Response Sheet 02/05/22, 8:48 PM

List I List II

Buffers pH Value

A. HCl and KCl I. 8 to 10

B. HCl and Potassium Hydrogen II. 2.2 to

Phthalate 4.0

C. NaOH and Potassium Hydrogen III. 1.2 to

Phthalate 2.2

D. H3BO3, NaOH, and KCl IV. 4.2 to

5.8

Choose the correct answer from the options given below:

Options:-
.A -II , B -III , C -IV , D -I , Option ID :- 261,
. A -III , B -II , C -IV , D -I , Option ID :- 262,
. A -II , B -IV , C -I , D -II , Option ID :- 263,
. A -III , B -IV , C -II , D -I , Option ID :- 264,
Answer Given:- A -III , B -II , C -IV , D -I , Option ID : -262

Question ID:- 49

Given below are two statements, one is labelled as Assertion A and the
other is labelled as

Reason R

Assertion A: During the process of decompression in tablet

manufacturing, expansion occurs in

some tablet.

Reason R: Expansion occurs in some tablet because of Plastic

deformation that has occurred

during compression process.

In light of the above statements, choose the correct answer from the
options given below

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 18 of 48
Response Sheet 02/05/22, 8:48 PM

Options:-
.Both A and R are true and R is the correct explanation of A , Option ID
:- 193,
. Both A and R are true but R is NOT the correct explanation of A ,
Option ID :- 194,
. A is true but R is false , Option ID :- 195,
. A is false but R is true , Option ID :- 196,
Answer Given:- Both A and R are true and R is the correct explanation of
A , Option ID : -193

Question ID:- 56

Decrease in effective surface area available to the dissolution medium

leading to a fall in the

dissolution rate, may happen due to which one of the following reasons?

Options:-
.Addition of cyclodextrin , Option ID :- 221,
. Addition of surfactant to increase the surface tension , Option ID :-
222,
. Addition of hydrophilic diluent , Option ID :- 223,
. Surface charges due to extreme particle size reduction , Option ID :-
224,
Answer Given:- Surface charges due to extreme particle size reduction ,
Option ID : -224

Question ID:- 46

___________ is the practice of pharmacy in private and government-

owned hospitals, health

maintenance organizations (HMOs), clinics, walk-in health centers, and

nursing homes.

Options:-
.Community pharmacy , Option ID :- 181,
. Government service , Option ID :- 182,
. Health-systems pharmacy , Option ID :- 183,
. Organizational management , Option ID :- 184,
Answer Given:- Community pharmacy , Option ID : -181

Question ID:- 69

Which of the following materials are specified as a suitable diluent for

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 19 of 48
Response Sheet 02/05/22, 8:48 PM

powdered opium

A. Powdered grass

B. Powdered cocoa husk

C. Lactose colored with burnt sugar

D. Powdered digitalis

Choose the correct answer from the options given below:

Options:-
.A and D only , Option ID :- 273,
. B and D only , Option ID :- 274,
. B and C only , Option ID :- 275,
. A and C only , Option ID :- 276,
Answer Given:- B and D only , Option ID : -274

Question ID:- 65

The temperature at which the solubility of the surfactant is equal to the

CMC, is called as

Options:-
.Critical micellar concentration , Option ID :- 257,
. Kraft point , Option ID :- 258,
. Cloud point , Option ID :- 259,
. Solubilization , Option ID :- 260,
Answer Given:- Kraft point , Option ID : -258

Question ID:- 68

Which of the following instrument is used to determine surface area and

pore structure of

pharmaceutical powders?

Options:-
.Coulter counter , Option ID :- 269,
. Andrerson apparatus , Option ID :- 270,
. Quantasorb , Option ID :- 271,
. Optical microscopy , Option ID :- 272,
Answer Given:- Coulter counter , Option ID : -269

Question ID:- 43

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 20 of 48
Response Sheet 02/05/22, 8:48 PM

Stability index, determined for evaluating the stability of oil–water

viscous emulsions, based on

electric conductivity changes during non-destructive short heating–

cooling–heating cycles,

A. is defined as Δ/h, where h is the change in the conductivity between

35°C and 45°C and Δ is

the conductivity interval within the two heating curves at 35°C

B. indicates the relative change in enthalpy between two cycles

C. is defined as 2Δ/h, where h is the change in the conductivity between

35°C and 45°C and Δ is

the conductivity interval within the two heating curves at 35°C

D. indicates the relative change in conductivity between two cycles

Choose the correct answer from the options given below:

Options:-
.
A and B only , Option ID :- 169,

. B and C only , Option ID :- 170,

. C and D only , Option ID :- 171,
. D and A only , Option ID :- 172,
Answer Given:- D and A only , Option ID : -172

Question ID:- 72

Which of the following statement is false?

Options:-
.Reducing agents often cause fading of dyes , Option ID :- 285,
. Anionic dyes are the most stable at acid pHs , Option ID :- 286,
. Basic dyes are not sensitive to alkalies , Option ID :- 287,
. Cationic dyes may be precipitated by soaps and clays , Option ID :-
288,
Answer Given:- Reducing agents often cause fading of dyes , Option ID :
-285

Question ID:- 64

Which of the following is most appropriate to crystalline solid?

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 21 of 48
Response Sheet 02/05/22, 8:48 PM

Options:-
.Give diffraction bands , Option ID :- 253,
. Characteristics geometrical shapes , Option ID :- 254,
. Sharp melting point , Option ID :- 255,
. All of these , Option ID :- 256,
Answer Given:- All of these , Option ID : -256

Question ID:- 44

Given below are two statements, one is labelled as Assertion A and the
other is labelled as

Reason R

Assertion A: The pressure filling method for filling pharmaceutical

aerosol is usually preferred

over cold filling method

Reason R: Because with pressure filling method high production speed

can be achieved and less

propellant is lost.

In light of the above statements, choose the correct answer from the
options given below

Options:-
.Both A and R are true and R is the correct explanation of A , Option ID
:- 173,
. Both A and R are true but R is NOT the correct explanation of A ,
Option ID :- 174,
. A is true but R is false , Option ID :- 175,
. A is false but R is true , Option ID :- 176,
Answer Given:- Both A and R are true and R is the correct explanation of
A , Option ID : -173

Question ID:- 39

Which of the following is an example of a thermosetting plastic material?

Options:-
.PVC , Option ID :- 153,

. Polyester , Option ID :- 154,

. Polypropylene , Option ID :- 155,
https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 22 of 48
Response Sheet 02/05/22, 8:48 PM

. Urethanes , Option ID :- 156,

Answer Given:- Polyester , Option ID : -154

Question ID:- 61

Which of the following conjugation reactions DOES NOT REQUIRE

reaction with an activated

conjugating agent?

Options:-
.Glucouronidation , Option ID :- 241,
. Sulfation , Option ID :- 242,
. Methylation , Option ID :- 243,
. Glutathione conjugation , Option ID :- 244,
Answer Given:- Sulfation , Option ID : -242

Question ID:- 40

Which of the following vehicles (not required to be sterile, but must be

pyrogen free) is intended to be used in the manufacture of injectable
products to be sterilized after preparation?

Options:-
.Purified Water , Option ID :- 157,
. Water for Injection USP , Option ID :- 158,
. Sterile Water for Injection USP , Option ID :- 159,
. Bacteriostatic Water for Injection USP , Option ID :- 160,
Answer Given:- Bacteriostatic Water for Injection USP , Option ID : -160

Question ID:- 76

Match List I with List II

List I List II

Antigen- antibody reaction

Application
types

I. Screening for Rubella and Type2 Herpes

A. Precipitin test
viruses

B. Agglutination II. Streptococcal differentiation into

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 23 of 48
Response Sheet 02/05/22, 8:48 PM

(Haemagglutination) serological groups

C. Complement Fixation III. Serological diagnosis of influenza &

reaction mumps viruses

D. ELISA IV. Treponema pallidum identification

V. Mycobacterium identification

Choose the correct answer from the options given below:

Options:-
.A -III , B -V , C -II, D -I , Option ID :- 301,
. A -II , B -IV , C -I , D -III , Option ID :- 302,
. A -IV , B -II , C -III , D -I , Option ID :- 303,
. A -I , B -III , C -II , D -IV , Option ID :- 304,
Answer Given:- A -II , B -IV , C -I , D -III , Option ID : -302

Question ID:- 59

The intracellular fluid volume including those of the blood cells is

approximately

Options:-
.15 litres , Option ID :- 233,
. 20 litres , Option ID :- 234,
. 27 litres , Option ID :- 235,
. 35 litres , Option ID :- 236,
Answer Given:- 15 litres , Option ID : -233

Question ID:- 75

Match List I with List II

List I List II

Classification of Bacteria Example

A. Gram positive spherical shaped nonmotile

bacteria I. Clostridium tetani

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 24 of 48
Response Sheet 02/05/22, 8:48 PM

B. Gram positive sporulating obligate II. Bacillus anthracis

anaerobic bacteria

C. Gram positive rod shaped nonsporulating

III. Streptococcus sp..
bacteria

D. Gram positive sporulating rod shaped IV. Corynebacterium

motile bacteria diphtheriae

V. E.coli

Choose the correct answer from the options given below:

Options:-
.A -III , B -IV , C -I , D - V , Option ID :- 297,
. A IV, B -I , C -II , D - III , Option ID :- 298,
. A -III , B - I, C -IV , D -II , Option ID :- 299,
. A -I , B -IV , C -II , D -III , Option ID :- 300,
Answer Given:- A -I , B -IV , C -II , D -III , Option ID : -300

Question ID:- 74

Which of the following statements are true

A. Bacteria are categorized underneath the Kingdom Monera.

B. Protista are unicellular and eukaryotic organisms.

C. Yeasts and molds are under kingdom Fungi

D. Multinucleated higher fungi are under Animalia

Choose the correct answer from the options given below:

Options:-
.A, B and C only , Option ID :- 293,
. B, C and D only , Option ID :- 294,
. A and B only , Option ID :- 295,
. C and D only , Option ID :- 296,
Answer Given:- A, B and C only , Option ID : -293

Question ID:- 48

In the process of sugar coating, to prevent moisture penetration into the

tablet core, which one of

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 25 of 48
Response Sheet 02/05/22, 8:48 PM

the following step is performed?

Options:-
.Seal Coating , Option ID :- 189,
. Subcoating , Option ID :- 190,
. Syrup Coating , Option ID :- 191,
. Polishing , Option ID :- 192,
Answer Given:- Seal Coating , Option ID : -189

Question ID:- 50

Statement I: The problem of declining potency in an unstable preparation

can be ameliorated by

the addition of an excess or overage of the active ingredient.

Statement II: Overages, are added to pharmaceutical formulations to

keep the content of the

active ingredient well above the limit, compatible with therapeutic

requirements, for a

predetermined period of time.

Options:-
.Both Statement I and Statement II are correct , Option ID :- 197,
. Both Statement I and Statement II are incorrect , Option ID :- 198,
.
Statement I is correct but Statement II is incorrect , Option ID :-
199,

. Statement I is incorrect but Statement II is correct , Option ID :- 200,

Answer Given:- Both Statement I and Statement II are correct , Option
ID : -197

Question ID:- 47

Given below are two statements, one is labelled as Assertion A and the
other is labelled as

Reason R

Assertion A: In the manufacturing of glycero-gelatin suppositories,

overfilling of mould is

necessary.

Reason R: Glycero-gelatin bases contract very little on cooling and the

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 26 of 48
Response Sheet 02/05/22, 8:48 PM

excess cannot be neatly

removed.

In light of the above statements, choose the correct answer from the
options given below

Options:-
.Both A and R are true and R is the correct explanation of A , Option ID
:- 185,
. Both A and R are true and R is the correct explanation of A , Option ID
:- 186,
. A is true but R is false , Option ID :- 187,
. A is false but R is true , Option ID :- 188,
Answer Given:- Both A and R are true and R is the correct explanation of
A , Option ID : -185

Question ID:- 67

Select correct option for miscible solvents?

A. Water and alcohol

B. Acetone and alcohol

C. Water and benzene

D. Carbon tetrachloride and benzene

Choose the correct answer from the options given below:

Options:-
.A and B only , Option ID :- 265,
. A, B and C only , Option ID :- 266,
. A, B and D only , Option ID :- 267,
. A and D only , Option ID :- 268,
Answer Given:- A, B and D only , Option ID : -267

Question ID:- 45

In the process of extraction, if maceration is accomplished by heating the

drug and solvent in a

close vessel, then this modification is known as _______

Options:-
.Digestion , Option ID :- 177,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 27 of 48
Response Sheet 02/05/22, 8:48 PM

. Refining , Option ID :- 178,

. Expression , Option ID :- 179,
. Rendering , Option ID :- 180,
Answer Given:- Rendering , Option ID : -180

Question ID:- 54

In the process of adding lubricant to a granulation, the lubricant is

divided finely by passing it

through 60-100 mesh nylon cloth on to the granulation, in production

this process is called as

________ the lubricant

Options:-
.Bolting , Option ID :- 213,
. Mixing , Option ID :- 214,
. Tumbling , Option ID :- 215,
. Grinding , Option ID :- 216,
Answer Given:- Mixing , Option ID : -214

Question ID:- 42

Which of the following DRYERS is a "static bed dryer"?

Options:-
.Freeze dryer , Option ID :- 165,
. Fluid bed dryer , Option ID :- 166,
. Spray dryer , Option ID :- 167,
. Flash dryer , Option ID :- 168,
Answer Given:- Fluid bed dryer , Option ID : -166

Question ID:- 63

In human body ----- system operates to maintain pH of blood plasma.

Options:-
.The acetate buffer , Option ID :- 249,
. The lysis buffer , Option ID :- 250,
. The potassium citrate , Option ID :- 251,
. The carbonic acid , Option ID :- 252,
Answer Given:- The lysis buffer , Option ID : -250

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 28 of 48
Response Sheet 02/05/22, 8:48 PM

Question ID:- 60

Match List I with List II

List I List II

A. When two dosage forms have equal I. When their total body
tmax clearance is constant.

B. AUC values of the two analogs can

II. Absorption rate constants are
be compared to measure relative
equal
bioavailability.

C. Urinary data is valid to measure III. When fraction absorbed and

bioavailability. elimination rate is constant.

IV. Excretion of drug and/or

D. Cmax is proportional to the rate of
metabolite is related to the
absorption.
bioavailable dose.

Choose the correct answer from the options given below:

Options:-
.A - II, B -I , C -IV- , D - III , Option ID :- 237,
. A -I , B -II , C -III , D -IV , Option ID :- 238,
. A -I, B -IV, C -III, D -II , Option ID :- 239,
. A -III , B -I , C -II , D -IV , Option ID :- 240,
Answer Given:- A -I , B -II , C -III , D -IV , Option ID : -238

Question ID:- 62

The below mentioned complex is not the type of inclusion compounds

Options:-
.Channel-Lattice type , Option ID :- 245,
. Quinhydrone complex , Option ID :- 246,
. Layer type , Option ID :- 247,
. Clathrates , Option ID :- 248,
Answer Given:- Clathrates , Option ID : -248

Question ID:- 55

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 29 of 48
Response Sheet 02/05/22, 8:48 PM

Which of the following is NOT a cause for the drug undergoing nonlinear
pharmacokinetics

Options:-
.Enzyme inhibition , Option ID :- 217,
. Enzyme induction , Option ID :- 218,
. Saturation of carrier molecules , Option ID :- 219,
. Saturation of plasma protein binding , Option ID :- 220,
Answer Given:- Enzyme induction , Option ID : -218

Question ID:- 52

Which one of the following is a rate equation for second order

bimolecular reaction if, a and b

are the initial concentrations of A and B, respectively, and x is the

concentration of each species

reacting in time t and k is second-order reaction

Options:-
.k = [2.303/ t(a − b)] x [log a(a − x) / b(b − x) ] , Option ID :- 205,
. k = [2.303/ t(a − b)] x [log b(a − x) / a(b − x) ] , Option ID :- 206,
. k = [2.303/ t(a − b)] / [log b(a − x) / a(b − x) ] , Option ID :- 207,
. k = [2.303/ t(a − b)] / [log a(a − x) / b(b − x) ] , Option ID :- 208,
Answer Given:- k = [2.303/ t(a − b)] / [log a(a − x) / b(b − x) ] ,
Option ID : -208

Question ID:- 57

Oral efficacy of Sabin Polio Vaccine can be adequately explained by

which of the following

processes of absorption?

Options:-
.Passive diffusion , Option ID :- 225,
. Active transport , Option ID :- 226,
. Ion - pair transport , Option ID :- 227,
. Pinocytosis , Option ID :- 228,
Answer Given:- Passive diffusion , Option ID : -225

Question ID:- 41

A typical skin cream consisting of stearic acid, potassium hydroxide,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 30 of 48
Response Sheet 02/05/22, 8:48 PM

glycerin, water,

preservative and perfume, would be commonly known as:

Options:-
.Cold cream , Option ID :- 161,
. Vanishing cream , Option ID :- 162,
. Foundation cream , Option ID :- 163,
. All purpose cream , Option ID :- 164,
Answer Given:- All purpose cream , Option ID : -164
Subject : Pharmacognosy SET 02

Question ID:- 78

Anthranilic acid is an immediate precursor in the formation of

Options:-
.Tyrosine , Option ID :- 309,
. Tryptophan , Option ID :- 310,
. Ornithine , Option ID :- 311,
. Methidine , Option ID :- 312,
Answer Given:- Tyrosine , Option ID : -309

Question ID:- 86

Dioscin, a steroidal saponin glycoside of Dioscorea tubers after

hydrolysis gives-

Options:-
.Diosgenin + 3 Glucose , Option ID :- 341,
. Diosgenin + 3 Rhamnose , Option ID :- 342,
. Diosgenin + 2 Glucose + 1 Rhamnose , Option ID :- 343,
. Diosgenin + 1 Glucose + 2 Rhamnose , Option ID :- 344,
Answer Given:- Diosgenin + 2 Glucose + 1 Rhamnose , Option ID : -343

Question ID:- 83

A. Rutin is a Bioflavonoid.

B. Rutin is a flavonol glycosides

C. Rutin is used in Capillary bleeding

D. Rutin is used as Vitamin P

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 31 of 48
Response Sheet 02/05/22, 8:48 PM

Which of the above are true for Rutin?

Options:-
.A and B only , Option ID :- 329,
. A, B and C only , Option ID :- 330,
. A, B and D only , Option ID :- 331,
. All of these , Option ID :- 332,
Answer Given:- A, B and C only , Option ID : -330

Question ID:- 85

The best quality of the Lemon oil is obtained by using-

Options:-
.Hydrodistillation method , Option ID :- 337,
. Extraction method , Option ID :- 338,
. Enfleurage method , Option ID :- 339,
. Hand press method , Option ID :- 340,
Answer Given:- Hydrodistillation method , Option ID : -337

Question ID:- 77

HPTLC analysis is useful for following types of analysis of herbal drugs

A. Quantitative estimation of marker compound

B. Authentication of extracts

C. Detection of pesticides

D. Standardization of herbal drugs

Choose the correct answer from the options given below:

Options:-
.A, B and D only , Option ID :- 305,
. D only , Option ID :- 306,
. A and D only , Option ID :- 307,
. A, B, C and D , Option ID :- 308,
Answer Given:- A, B, C and D , Option ID : -308

Question ID:- 82

Rancidity in the fixed oils generally show -

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 32 of 48
Response Sheet 02/05/22, 8:48 PM

Options:-
.Higher Iodine value as compared to the standards , Option ID :- 325,
. Higher Acid value as compared to the standards , Option ID :- 326,
. Higher Peroxide value as compared to the standards , Option ID :- 327,
. Higher level of Unsaponifiable matter , Option ID :- 328,
Answer Given:- Higher Acid value as compared to the standards , Option
ID : -326

Question ID:- 79

Tropane nucleus is combination of

Options:-
.Pyrolidine & piperidine , Option ID :- 313,
. Pyrolidine & pyridine , Option ID :- 314,
. Pyrolidine & oscine , Option ID :- 315,
. Piperidine & oscine , Option ID :- 316,
Answer Given:- Pyrolidine & pyridine , Option ID : -314

Question ID:- 81

One of the following is an example of chemical method of evaluation

Options:-
.Determination of volatile oil , Option ID :- 321,
. Determination of refractive index , Option ID :- 322,
. Detection of alkaloids , Option ID :- 323,
. Determination of vascular bundles , Option ID :- 324,
Answer Given:- Determination of refractive index , Option ID : -322

Question ID:- 80

Type of alkaloids present in Colchicum

Options:-
.Tropane alkaloids , Option ID :- 317,
. Steroidal glycoalkaloids , Option ID :- 318,
. Amino alkaloids , Option ID :- 319,
. Quinoline alkaloids , Option ID :- 320,
Answer Given:- Quinoline alkaloids , Option ID : -320

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 33 of 48
Response Sheet 02/05/22, 8:48 PM

Question ID:- 84

‘Star spots’ present in the transverse section of decorticated Rhubarb

rhizomes are-

Options:-
.Lignified cells , Option ID :- 333,
. Pericyclic fibres , Option ID :- 334,
. Concentric vascular bundles , Option ID :- 335,
. Crystals of calcium oxalate , Option ID :- 336,
Answer Given:- Lignified cells , Option ID : -333

Subject : Pharmacology SET 02

Question ID:- 92

Match List I with List II

List I List II

(Poisoning) (Treatment)

1. Warfarin P. Pralidoxime

2. Carbon
Q. Oxygen
monoxide

3. Cyanide R. Vitamin K

S. Dicobalt
4. Nitrites
edatate

5. T. Methylene
Organophosphates blue

Choose the correct answer from the options given below:More text goes
here.

Options:-
.1:R, 2:Q, 3: S, 4: T, 5: P , Option ID :- 365,
. 1:P, 2:Q, 3: T, 4: S, 5: R , Option ID :- 366,
. 1:Q, 2:S, 3:P, 4:R, 5: T , Option ID :- 367,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 34 of 48
Response Sheet 02/05/22, 8:48 PM

. 1:T,
2:Q, 3: R, 4:P, 5:S , Option ID :- 368,
Answer Given:- 1:R, 2:Q, 3: S, 4: T, 5: P , Option ID : -365

Question ID:- 87

Match List I with List II Match the following drugs with their classes.

List I List II
Drugs Classes
A. I. IL-2 receptor
Anakinra antagonist
B.
II. TNF! inhibitors
Basiliximab
C. III. Calcineurin
Infliximab inhibitors
D. IV. mTOR
Tacrolimus inhibitors
V. IL-1 receptor
antagonist

More text goes here.

Choose the correct answer from the options given below:

Options:-
.A -III , B -II , C -I , D - IV , Option ID :- 345,
. A -V, B -II , C -III, D - I , Option ID :- 346,
. A -I , B -III , C -V , D -II , Option ID :- 347,
. A -V , B -I , C -II , D - III , Option ID :- 348,
Answer Given:- A -I , B -III , C -V , D -II , Option ID : -347

Question ID:- 113

Match the following phases of clinical trial with their significance

List I List II
A. P. Post marketing
Phase-I surveillance
B.
Q. Microdosing
Phase-0
C.
R. First in human dose
Phase-3
D.
S. Multicentric trials
Phase-4

Choose the correct answer from the options given below:

Options:-

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 35 of 48
Response Sheet 02/05/22, 8:48 PM

.A-R, B-Q, C-P, D-S , Option ID :- 449,

. A-R, B-Q, C-S, D-P , Option ID :- 450,
. A-Q, B-S, C-P, D-R , Option ID :- 451,
. A-S, B-P, C-Q, D-R , Option ID :- 452,
Answer Given:- A-R, B-Q, C-S, D-P , Option ID : -450

Question ID:- 89

Reason for the combination of Diphenoxylate (2.5 mg) + Atropine (0.025

mg) is to

Options:-
.Inhibits the side effects of Diphenoxylate , Option ID :- 353,
. Discourage abuse of Diphenoxylate , Option ID :- 354,
. Augment the anti-motility action of Diphenoxylate , Option ID :- 355,
. Suppress gastroenteritis-related vomiting , Option ID :- 356,
Answer Given:- Inhibits the side effects of Diphenoxylate , Option ID :
-353

Question ID:- 91

The ‘Up-and-Down’ method for a projected LD50 determination is

described in the…..

Options:-
.OECD Guideline 401 , Option ID :- 361,
. OECD Guideline 420 , Option ID :- 362,
. OECD Guideline 423 , Option ID :- 363,
. OECD Guideline 425 , Option ID :- 364,
Answer Given:- OECD Guideline 420 , Option ID : -362

Question ID:- 104

Which of the following clinical feature is not responsible for insulin

resistance in type 2 diabetes?

Options:-
.Increased LDL , Option ID :- 413,
. Increased HDL , Option ID :- 414,
. Reduced HDL , Option ID :- 415,
. Increased triglycerides , Option ID :- 416,
Answer Given:- Increased HDL , Option ID : -414

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 36 of 48
Response Sheet 02/05/22, 8:48 PM

Question ID:- 99

Which of the following is/are not true about Parkinson’s disease?

A. Parkinson’s disease is caused by the degeneration of the substantia

nigra in the midbrain.

B. Parkinson's disease is caused by the degenerative loss of nigrostriatal

dopaminergic neurons.

C. Bradykinesia, rigidity and tremor are the main symptoms in

Parkinson’s disease.

D. Parkinson's disease is caused by the degenerative loss of nigrostriatal

cholinergic neurons.

Choose the correct answer from the options given below:

Options:-
.A, B and D only , Option ID :- 393,
. A, B and D only , Option ID :- 394,
. C only , Option ID :- 395,
. D only , Option ID :- 396,
Answer Given:- C only , Option ID : -395

Question ID:- 103

Which of the following is a malignant type of tumor?

Options:-
.Lipoma , Option ID :- 409,
. Adenoma , Option ID :- 410,
. Melanoma , Option ID :- 411,
. Osteoma , Option ID :- 412,
Answer Given:- Osteoma , Option ID : -412

Question ID:- 90

Regarding Bromocriptine, which of the following statement is TRUE-

It is a relatively selective dopamine D2 agonist with prominent action

A. on pituitary lactotrophs (inhibit prolactin release)

B. in striatum (antiparkinsonian)

C. in CTZ (antiemetic)

D. as an adjunctive treatment for type 2 DM

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 37 of 48
Response Sheet 02/05/22, 8:48 PM

Choose the correct answer from the options given below:

Options:-
.A, B and D only , Option ID :- 357,
. A, B and C only , Option ID :- 358,
. B and D only , Option ID :- 359,
. A and B only , Option ID :- 360,
Answer Given:- A, B and D only , Option ID : -357

Question ID:- 88

Match List I with List II Match the following with their mechanism of
action

List I List II
Mechanism of action Drugs
A. DPP4 inhibitors I. Metformin
B. KATP Channel blocker II. Pioglitazone
C. PPARγ activator III. Glimepiride
D. AMPK Activator IV. Teneligliptin
V. !! glucosidase inhibitors

Choose the correct answer from the options given below:

Options:-
.A -II , B -V , C -III , D -IV , Option ID :- 349,
. A - II, B - III, C -IV , D -I , Option ID :- 350,
. A -IV , B -III , C -II , D -I , Option ID :- 351,
. A -IV, B - I, C -V , D -III , Option ID :- 352,
Answer Given:- A - II, B - III, C -IV , D -I , Option ID : -350

Question ID:- 112

Which of the following statements are true with the Adverse Drug
Reactions?

A. Any response to a drug which is noxious and unintended.

B. Which occurs at doses normally used in man for prophylaxis, diagnosis

or therapy of a disease.

C. Adverse drug event is same as that of Adverse Drug Reaction.

D. Which occurs at normal dose or overdose when used for prophylaxis,

diagnosis or therapy of a disease.

Choose the correct answer from the options given below:

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 38 of 48
Response Sheet 02/05/22, 8:48 PM

Options:-
.A and B are true while C and D are false. , Option ID :- 445,
. A and C are true while B and D are false. , Option ID :- 446,
. B, C and D are false, Only A is true. , Option ID :- 447,
. A, B and C are false, Only D is true. , Option ID :- 448,
Answer Given:- B, C and D are false, Only A is true. , Option ID : -447

Question ID:- 109

Blood grouping is basically possible because of the presence of following:

Options:-
.Antigens on RBCs , Option ID :- 433,
. MHCs on WBCs , Option ID :- 434,
. MHCs on RBCs , Option ID :- 435,
. Antigens on WBCs , Option ID :- 436,
Answer Given:- Antigens on RBCs , Option ID : -433

Question ID:- 94

A neonate suffering from icterus is intravenously administered with

phenobarbital. The justification for this therapy is:

Options:-
.Phenobarbital is a short acting barbiturate and hence safe to induce
sleep in neonates , Option ID :- 373,
. Phenobarbital suppresses the bilirubin synthesis in neonates , Option
ID :- 374,
. Phenobarbital suppresses hepatic glucuronyl transferase and increases
clearance of bilirubin , Option ID :- 375,
. Phenoarbital induces hepatic glucuronyl transferase and increases
clearance of bilirubin , Option ID :- 376,
Answer Given:- Phenobarbital is a short acting barbiturate and hence
safe to induce sleep in neonates , Option ID : -373

Question ID:- 97

Which of the following statement/s are correct regarding the alkylating

agents as anticancer agents:

A. They get converted into highly nucleophilic anions and bind to the
nitrogen atom of guanine intercalating the DNA strands

B. Cyclophosphamide and busulfan belong to this class

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 39 of 48
Response Sheet 02/05/22, 8:48 PM

C. They inhibit the DNA synthesis by inhibiting the DNA polymerase

enzyme

D. They inhibit the DNA supercoiling by irreversibly inhibiting the DNA

topoisomerase enzyme

Choose the correct answer from the options given below:

Options:-
.A, B and D only are correct , Option ID :- 385,
. Only B is correct , Option ID :- 386,
. Only A and B are correct , Option ID :- 387,
. All A, B, C and D are correct , Option ID :- 388,
Answer Given:- Only B is correct , Option ID : -386

Question ID:- 114

The objective of the Abbreviated New Drug Application is to …

Options:-
.get approval to conduct clinical trials , Option ID :- 453,
. get market approval of new chemical entities , Option ID :- 454,
. get market approval of generics , Option ID :- 455,
. get approval for animal studies of new chemical entities , Option ID :-
456,
Answer Given:- get approval to conduct clinical trials , Option ID : -453

Question ID:- 105

Formation and maintenance of myelin sheath around CNS axons are done
by

Options:-
.Schwann cells , Option ID :- 417,
. Oligodendrocytes , Option ID :- 418,
. Microglia , Option ID :- 419,
. Astrocytes , Option ID :- 420,
Answer Given:- Schwann cells , Option ID : -417

Question ID:- 98

Nitric oxide synthase exists in __________

Options:-
.Two isoforms , Option ID :- 389,
https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 40 of 48
Response Sheet 02/05/22, 8:48 PM

. Three isoforms , Option ID :- 390,

. Four isoforms , Option ID :- 391,
. Five isoforms , Option ID :- 392,
Answer Given:- Two isoforms , Option ID : -389

Question ID:- 108

Which of the following statement is true for the periosteum of bone

Options:-
.Protects the bone by assisting in fracture repair , Option ID :- 429,
. Has osteogenic cells which enable bone to grow in thickness, but not in
length , Option ID :- 430,
. It is composed of an outer fibrous layer of dense irregular connective
tissue and an inner osteogenic layer that consists of cells , Option ID :-
431,
. All of these , Option ID :- 432,
Answer Given:- All of these , Option ID : -432

Question ID:- 106

At the site of tissue injury, the activated platelet releases ADP and
activates surrounding platelets to form platelet-plug, but this process
will not continue to activate whole platelets in the body to form a
massive ball of platelets because

Options:-
.The adjacent normal endothelial cells physiologically release ‘NO’ which
is a platelet inhibitor , Option ID :- 421,
. There will be plasminogen activators in the plasma , Option ID :- 422,
. There will be plasminogen activator inhibitors in plasma , Option ID :-
423,
. There will be a tissue plasminogen activator (tPA) which inhibits the
platelets , Option ID :- 424,
Answer Given:- There will be plasminogen activators in the plasma ,
Option ID : -422

Question ID:- 107

When RBCs are kept in isotonic NaCl solution

Options:-
.There will not be any movement of solutes across the RBC membrane ,
Option ID :- 425,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 41 of 48
Response Sheet 02/05/22, 8:48 PM

. The RBC shape and size will not change , Option ID :- 426,
. Because the osmotic pressure across the membrane is same the
solutes will not cross across the RBC membrane , Option ID :- 427,
. All of these , Option ID :- 428,
Answer Given:- All of these , Option ID : -428

Question ID:- 95

Tendon rupture or tendonitis of Achilles tendon is an adverse reaction of

Options:-
.Fluoroquinolones , Option ID :- 377,
. Tetracyclines , Option ID :- 378,
. Cephalosporins , Option ID :- 379,
. Aminoglycosides , Option ID :- 380,
Answer Given:- Fluoroquinolones , Option ID : -377

Question ID:- 93

A patient with pheochromcytoma is undergoing surgery and has not been

administered with alpha receptor blocker. If he is administered with
intravenous propranolol, then which of the following effects will be
evident?

Options:-
.There will be a rise in the blood pressure , Option ID :- 369,
. There will be a fall in the blood pressure , Option ID :- 370,
. The blood pressure will remain unchanged , Option ID :- 371,
. The patient may suffer severe bronchoconstriction , Option ID :- 372,
Answer Given:- There will be a rise in the blood pressure , Option ID :
-369

Question ID:- 111

Which of the following could be the reason(s) for Pharmacokinetic Drug

Interactions?

A. Interference with absorption

B. Changes in protein binding

C. Competition at receptor sites

D. Interference with renal excretion

Choose the correct answer from the options given below:

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 42 of 48
Response Sheet 02/05/22, 8:48 PM

Options:-
.A, B and C only , Option ID :- 441,
. A, B and D only , Option ID :- 442,
. A, C and D only , Option ID :- 443,
. C only , Option ID :- 444,
Answer Given:- A, C and D only , Option ID : -443

Question ID:- 101

Which of the following type is a reversible cell injury?

Options:-
.Karyolysis , Option ID :- 401,
. Nuclear clumping , Option ID :- 402,
. Phagocytosis , Option ID :- 403,
. Cytoskeletal damage , Option ID :- 404,
Answer Given:- Phagocytosis , Option ID : -403

Question ID:- 110

Which of the statement is true in geriatrics practice?

Options:-
.The incidence of Adverse Drug Reactions diminishs with advancement
of age. , Option ID :- 437,
. Dose reduction is inevitable for each and every drug used in geriatric
patients. , Option ID :- 438,
. Patient compliance is highest in geriatric patients. , Option ID :- 439,
. Polypharmacy is often a problem in elderly. , Option ID :- 440,
Answer Given:- Dose reduction is inevitable for each and every drug used
in geriatric patients. , Option ID : -438

Question ID:- 96

The quadruple therapy of Helicobacter pylori infection includes

Options:-
.Bismuth subsalicylate, metronidazole, tetracycline and a proton pump
inhibitor , Option ID :- 381,
. Streptomycin, metronidazole, tetracycline and a proton pump inhibitor
, Option ID :- 382,
. Sulfasalazine, metronidazole, tetracycline and a proton pump inhibitor
https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 43 of 48
Response Sheet 02/05/22, 8:48 PM

, Option ID :- 383,
. Bismuth subsalicylate, metronidazole, azithromycin and a proton pump
inhibitor , Option ID :- 384,
Answer Given:- Bismuth subsalicylate, metronidazole, azithromycin and a
proton pump inhibitor , Option ID : -384

Question ID:- 102

Which of the following is a specific enzyme marker of cell death in acute

myocardial infarction?

Options:-
.Creatine Kinase-MB , Option ID :- 405,
. Aspartate aminotransferase , Option ID :- 406,
. Lactate dehydrogenase , Option ID :- 407,
. Cardiac troponin , Option ID :- 408,
Answer Given:- Cardiac troponin , Option ID : -408

Question ID:- 100

Which statements are not true about the grafts?

A. Isografts are grafts in which the donor and recipient is the same
individual.
B. Autografts are grafts between the donor and recipient of the same
genotype.
C. Allografts are those in which the donor is of the same species but of a
different genotype
D. Xenografts are those in which the donor is of a different species from
that of the recipient.
Choose the correct answer from the options given below:

Options:-
.A, B and D only , Option ID :- 397,
. A and B , Option ID :- 398,
. B and C , Option ID :- 399,
. C and D , Option ID :- 400,
Answer Given:- A, B and D only , Option ID : -397

Subject : Other Subjects SET 02

Question ID:- 123

Water for injection is prepared by using_________distillation.

Options:-
.Fractional , Option ID :- 489,

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 44 of 48
Response Sheet 02/05/22, 8:48 PM

. Molecular , Option ID :- 490,

. Simple , Option ID :- 491,
. Steam , Option ID :- 492,
Answer Given:- Simple , Option ID : -491

Question ID:- 117

Given below are two statements

Statement I: Drugs Controller General of India is the Chairman of Drugs

Technical Advisory Board (DTAB)

Statement II: In DTAB, there will be eight ex-officio members, five

nominated and five elected members

In light of the above statements, choose the most appropriate answer

from the options given below

Options:-
.Both Statement I and Statement II are correct , Option ID :- 465,
. Both Statement I and Statement II are incorrect , Option ID :- 466,
. Statement I is correct but Statement II is incorrect , Option ID :- 467,
. Statement I is incorrect but Statement II is correct , Option ID :- 468,
Answer Given:- Both Statement I and Statement II are correct , Option
ID : -465

Question ID:- 120

Given below are two statements

Statement I: Sequencing of DNA is much easier than RNA sequencing due

to greater stability

Statement II: The chemical method of DNA sequencing (Maxam &

Gilbert) works for only single stranded DNA

In light of the above statements, choose the correct answer from the
options given below

Options:-
.Both Statement I and Statement II are true , Option ID :- 477,
. Both Statement I and Statement II are false , Option ID :- 478,
. Statement I is true but Statement II is false , Option ID :- 479,
. Statement I is false but Statement II is true , Option ID :- 480,
Answer Given:- Both Statement I and Statement II are true , Option ID :
-477

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 45 of 48
Response Sheet 02/05/22, 8:48 PM

Question ID:- 115

India’s first Central Drug Laboratory was established at

Options:-
.Mumbai , Option ID :- 457,
. Lucknow , Option ID :- 458,
. Kolkata , Option ID :- 459,
. Hyderabad , Option ID :- 460,
Answer Given:- Hyderabad , Option ID : -460

Question ID:- 116

As per the Pharmacy Act, in the composition of Pharmacy Council of

India, the total number of Ex-officio members is

Options:-
.THREE , Option ID :- 461,
. FOUR , Option ID :- 462,
. SIX , Option ID :- 463,
. EIGHT , Option ID :- 464,
Answer Given:- SIX , Option ID : -463

Question ID:- 124

Boston Consulting Group (BCG) Matrix is used for

Options:-
.Product life cycle management , Option ID :- 493,
. SWOT analysis , Option ID :- 494,
. Product portfolio management , Option ID :- 495,
. Gap analysis , Option ID :- 496,
Answer Given:- SWOT analysis , Option ID : -494

Question ID:- 121

Match List I of Unit operations of crystallizers with List II of

principle/characteristics properties of crystallizer

Crystallizer Principle/Characteristics

Unit operations Properties

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 46 of 48
Response Sheet 02/05/22, 8:48 PM

A. Swenson-walker crystallizer I. Adiabatic evaporative cooling

B.Krystal crystallizer II. Cooling alone

C. Vacuum crystallizer III. Evaporation

D. Forced circulation type IV. Heat exchange, separation,

crystallizer circulation

Choose the correct answer from the options given below:

Options:-
.A -I , B -II , C -IV , D -III , Option ID :- 481,
. A -III , B -I , C -IV , D -II , Option ID :- 482,
. A -I , B -IV , C -III , D -II , Option ID :- 483,
. A -II , B -III , C -I , D -IV , Option ID :- 484,
Answer Given:- A -I , B -IV , C -III , D -II , Option ID : -483

Question ID:- 122

Given below are two statements

Statement I: Vertical long tube evaporator is also called as Rising film

evaporator

Statement II: Falling film evaporator is also called as Forced circulation

type evaporator

In light of the above statements, choose the most appropriate answer

from the options given below

Options:-
.Both Statement I and Statement II are correct , Option ID :- 485,
. Both Statement I and Statement II are incorrect , Option ID :- 486,
. Statement I is correct but Statement II is incorrect , Option ID :- 487,
. Statement I is incorrect but Statement II is correct , Option ID :- 488,
Answer Given:- Both Statement I and Statement II are correct , Option
ID : -485

Question ID:- 119

Viable cells (viability assay) are assayed by all of the following methods
except

Options:-

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 47 of 48
Response Sheet 02/05/22, 8:48 PM

.MTT/MTS/Resazurin assay , Option ID :- 473,

. Apoptosis assay , Option ID :- 474,
. ATP assay , Option ID :- 475,
. Protease marker assay , Option ID :- 476,
Answer Given:- MTT/MTS/Resazurin assay , Option ID : -473

Question ID:- 118

Of the following, which one is exempted from importing into India

without the requirement of a license?

Options:-
.Insulin , Option ID :- 469,
. Etoposide , Option ID :- 470,
. Lactose , Option ID :- 471,
. Glutethimide , Option ID :- 472,
Answer Given:- Lactose , Option ID : -471

Question ID:- 125

The process of establishing a product in the minds of target customer is

called as

Options:-
.Product positioning , Option ID :- 497,
. Product differentiation , Option ID :- 498,
. Product targeting , Option ID :- 499,
. Market segmentation , Option ID :- 500,
Answer Given:- Product targeting , Option ID : -499

Print ResponseSheet

https://ntagpat2022.cbtexam.in/Candidate/ResponseSheet.aspx?…3cb167-7b04-46ba-b1b7-afad2461e9e2&Rollno=HR03000126&PgId=74 Page 48 of 48