Scribd
Upload
2K views1 page

Linagliptin - DRUG STUDY

Linagliptin is a DPP-4 inhibitor indicated for treatment of type 2 diabetes. It works by inhibiting the enzyme DPP-4, which degrades the incretin hormones GLP-1 and GIP. Linagliptin is contraindicated in patients with a history of hypersensitivity and should be discontinued if signs of pancreatitis develop. Nurses should monitor patients treated with linagliptin for hypoglycemia and pancreatitis.

Uploaded by

Acads use
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
2K views1 page

Linagliptin - DRUG STUDY

Linagliptin is a DPP-4 inhibitor indicated for treatment of type 2 diabetes. It works by inhibiting the enzyme DPP-4, which degrades the incretin hormones GLP-1 and GIP. Linagliptin is contraindicated in patients with a history of hypersensitivity and should be discontinued if signs of pancreatitis develop. Nurses should monitor patients treated with linagliptin for hypoglycemia and pancreatitis.

Uploaded by

Acads use
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
You are on page 1/ 1

DRUG STUDY

Generic Name Classification and Indication Mechanism of Contraindications Side effects Nursing Considerations
Linagliptin Category action
Brand Name  Observe patient for
Trajenta A. Chemical: Indicated for the Linagliptin in is contraindicated in severe or signs and symptoms of
dipeptidyl treatment of an inhibitor of patients with a history ongoing pain in hypoglycemic reactions
peptidase-4 (DPP- type II diabetes DPP-4, an of hypersensitivity to your joints; (abdominal pain,
Available dosage
4) inhibitor in addition to enzyme that linagliptin, such as a severe sweating, hunger,
 5mgOD diet and degrade s the anaphylaxis, urticaria, autoimmune weakness, dizziness,
B. Therapeutic: anti- exercise. incretin angioedema, reaction-- headache, tremor,
hyperglycemic hormones exfoliative dermatitis itching, blisters, tachycardia, anxiety).
drugs glucagon-like or other serious breakdown of  Monitor for signs of
peptide-1 (GLP- allergic skin the outer layer pancreatitis (nausea,
1) and glucose condition (serious of skin; or. vomiting, anorexia,
depend ent rash), or bronchial symptoms of persistent severe
insulino tropic hypersensitivity. heart failure-- abdominal pain,
polypep tide shortness of sometimes radiating to
Route PO (GIP). breath (even the back) during
Frequency OD while lying therapy. If pancreatitis
down), swelling occurs, discontinue
Pharmacokinetics in your legs or linagliptin and monitor
 Onset: 1 hour feet, rapid serum and urine
 Peak: 1.5 hours weight gain. amylase,
 Duration: 12 hours amylase/creatinine
 Half Life: 100-155 clearance ratio,
hours electrolytes, serum
calcium, glucose, and
lipase

You might also like