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Drug Study: Nursing Department

This document provides information about the drug fluconazole, including its generic and brand names, indications, mechanism of action, drug interactions, contraindications, adverse effects, and nursing considerations. Fluconazole is an antifungal medication used to treat vaginal and oral thrush. It works by inhibiting the cytochrome P450 enzyme responsible for fungal sterol synthesis. Nurses should monitor patients for serious liver toxicity, rash, or other adverse reactions, especially those with underlying conditions or who are HIV-positive. Drug interactions can occur when taken with alprazolam, cimetidine, or other medications.

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1K views1 page

Drug Study: Nursing Department

This document provides information about the drug fluconazole, including its generic and brand names, indications, mechanism of action, drug interactions, contraindications, adverse effects, and nursing considerations. Fluconazole is an antifungal medication used to treat vaginal and oral thrush. It works by inhibiting the cytochrome P450 enzyme responsible for fungal sterol synthesis. Nurses should monitor patients for serious liver toxicity, rash, or other adverse reactions, especially those with underlying conditions or who are HIV-positive. Drug interactions can occur when taken with alprazolam, cimetidine, or other medications.

Uploaded by

giselle chloe
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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PHINMA UNIVERSITY OF PANGASINAN

COLLEGE OF HEALTH SCIENCES


Nursing Department

DRUG STUDY
DRUG
DRUG INDICATION ACTION CONTRAINDICATION ADVERSE EFFECT NURSING CONSIDERATION
INTERACTION
Generic Name: > indicated for the > inhibits fungal >alprazolam, > contraindicated in >CNS: headache, >Serious hepatoxicity may
fluconazole treatment of cytochrome chlordiazepoxide, patients hypersensitive dizziness. occur in patients with
Vaginal candidiasis p450 clonazepam, to drug and breast- >GI: N/V, underlying medical
(vaginal yeast (responsible for clorazepate, feeding patients. abdominal pain, conditions.
infections due to diazepam, >use cautiously in diarrhea, >if patient develops mild
fungal sterol
candida). estazolam. patients hypersensitive dyspepsia, taste rash, monitor him closely.
Brand Name: synthesis);
> Oropharyngeal Flurazepam, to other antifungal perversion. Stop drug if lesions progress.
Diflucan and esophageal weakens fungal midazolam, azole compounds. >Hematologic: >risk of adverse reactions
candidiasis. cells. quazepam, leukopenia, may be greater in HIV-
triazolam: may thrombocytopenia. infected patients.
Drug increase and >Skin: rash
Classification: prolong levels of >Other: anaphylaxis
Pregnancy risk these drugs, CNS
category C depression, and
psychomotor
impairment. Avoid
using together.
>Cimetidine: may
decrease
fluconazole level.
Monitor patient
response to
fluconazole.
>Cyclosporine,
phenytoin,
theophylline: may
increase levels of
these drugs.

SUBMITTED BY: Giselle Chloe B. Ico

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