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Metoclopramide DS

This document summarizes information about the drug Metoclopramide. It is a generic anti-emetic drug that works by blocking dopamine receptors in the brain and stimulating movement in the upper gastrointestinal tract. It is indicated for treating nausea, vomiting, and gastric stasis. Some potential drug interactions and adverse reactions are listed such as drowsiness, extrapyramidal effects, and depression. Nursing considerations include monitoring for side effects and assessing symptoms before and after administration.

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Angelica Idio
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4K views1 page

Metoclopramide DS

This document summarizes information about the drug Metoclopramide. It is a generic anti-emetic drug that works by blocking dopamine receptors in the brain and stimulating movement in the upper gastrointestinal tract. It is indicated for treating nausea, vomiting, and gastric stasis. Some potential drug interactions and adverse reactions are listed such as drowsiness, extrapyramidal effects, and depression. Nursing considerations include monitoring for side effects and assessing symptoms before and after administration.

Uploaded by

Angelica Idio
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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UNIVERSITY OF PANGASINAN-PEN COLLEGE OF NURSING Arellano St.

, Dagupan City

DRUG STUDY
DRUG NAME
Generic Name: METOCLOPRAMIDE

DRUG ACTION
Blocks dopamine receptors in chemorecep-tor trigger zone of CNS Stimulate motility of the upper GI tract and accelerates gastric emptying Therapeutic Effects: Decreased nausea and vomiting Decreased symptoms of gastric stasis Easier passage of nasogastric tube into the small bowel

INDICATIONS

CONTRAINDICATIONS

DRUG-DRUG INTERACTION
Additive CNS depression with other CNS depressants May increased absorption and risk of toxicity from cyphalospo-rin May affect the GI absorption of other orally administered drugs as a result of effect of GI motility May exaggerate hypotension during general anesthesia May increased neuromuscu-lar blockade from succinylcho-line May increased the effectiveness of levodopa.

ADVERSE REACTIONS
CNS: drowsiness, extrapyramidal reaction, restlessness, anxiety, depression, irritability, tartive dyskinesia CV: arrhythmias, hypertension, hypotension GI: constipation, diarrhea, dry mouth, nausea Endo: gynecomastia

NURSING CONSIDERATIONS
Assess patient for nausea, vomiting, abdominal distention, and bowel sounds before and after administra-tion Assess patient for extrapyramidal side effects periodically throughout course of therapy Monitor tardive dyskinesia . usually occur after a year or more or continued therapy Assess patient for signs of depression periodically throughout therapy.

Brand Name: REGLAN

Classification ANTIEMETIC

Prevention of Hypersensitivity chemotherapy Possible GI induced emesis obstruction or Treatment of hemorrhage postsurgical and History of seizure diabetic gastric disorders stasis Pheochromocy-toma Facilitation of Parkinsons disease small bowel intubation in Use Cautiously in: radiographic History of depression procedures Diabetes Management of Pregnancy and esophageal reflux lactation Treatment and Children and geriatric prevention of patients postoperative nausea and vomiting when nasogastric suctioning is undesirable Treatment of hiccups Adjuct management of migraine headaches

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