Management of Eyelid Defect
Management of Eyelid Defect
ABSTRACT
Eyelids are the protective mechanism of the eyes. The upper and lower eyelids have been formed
for their specific functions by Nature. Reconstruction of the eyelids is highly complex because
of their function and critical role in appearance. Optimal restoration of their form and function
depends on a firm understanding of normal eyelid position, the structural support system of the
eyelids, and the forces that act to keep the eyelids in precise balance. The surgical repair of eyelid
defect differs somewhat from that of most skin lacerations. The reasons for this include the need to
maintain a functional eyelid and ensure a cosmetic outcome as well as the fact that the eyelid is more
vascularized than many other skin regions. A functional upper eyelid is essential to maintain the
health of the globe itself. If the eyelid is incomplete or immobile, it is unable to physically protect the
eye and is unable to spread the tear film over the ocular surface.
INTRODUCTION
    Eyelids are complex structures and pose             firmly adherent over the pretarsal area and
a challenge for reconstruction. They play an            over the medial and lateral canthal areas due
important role in protecting the globe from             to the absence of subcutaneous tissue. It is
trauma, excessive light, and in maintaining             lined with the conjunctiva on the inner side
the integrity of tear films and moving the tears        and supported in the middle by the tarsal plate.
toward the lacrimal drainage system. The                The conjunctiva is firmly adherent over the
beauty and expression to the eye is given by the        tarsal plates, loose above it and while lining
lids and muscles in it. Upper and lower eyelids         the fornices. The lid margin is about 2 mm
have been formed for their specific functions           in width and represents the transitional zone
by Nature. To undertake the reconstruction of           of the skin and conjunctiva. This junction is
the eyelids, it is very important to understand         called the grey line and through it the lid can
few basic anatomical features of the eyelids.[1]        be split into anterior lamella and posterior
                                                        lamella. The anterior lamella consists of the
Pertinent Anatomy                                       skin and orbicularis muscle. The posterior
   The outermost layer of the eyelid is skin.           lamella consists of the conjunctiva and tarsal
The skin of the eyelid is very unique and is            plate. The posterior edge of the lid margin is
the thinnest in the body. It becomes thicker            sharper compared to the anterior edge which
as it approaches the eyebrow and cheek. It is           is rounded. There are two rows of lashes in the
lower lid and three to four rows in the upper         is done to get properly alignet lid.
lid. [1]
    Beneath skin is the orbicularis muscle, the
contraction of which closes the eyelid. The
orbital septum is a fibrous sheet that lies beneath
the orbicularis muscle. This important structure
acts as a barrier between superficial preseptal
tissues and postseptal orbital anatomy. More
posteriorly, orbital fat separates the orbital           Figure 1. Eyelid margin architecture[3]
septum from the levator muscle which is the              Principles of lid repair[4]
main retractor of the eyelid. Mueller‟s muscle        • Clean the wound at initial repair to remove
also aids the levator in elevation of the eyelid.        dirt or foreign body to prevent subsequent
The conjunctiva lines the inner aspect of the            tattooing.
eyelid and contacts the ocular surface[2] .           • All wounds are examined carefully and any
    Eyelid margin has slightly rounded anterior          visible damage repaired.
edge and sharp posterior edge. Anatomical             • Reconstruction should be done in layers as
structures in eyelid margin from posterior to            per correct anatomical orientation.
anterior are (Figure 1)[3].                           • Skin incision given along line of tension. In
    • Mucocutaneous junction                             lower lid line of incision should be oriented
    • Meibomian gland orifices                           perpendicular to lid margin.
    • Gray line                                       • Cut „Down hill to Up hill‟ to prevent blood
    • Eyelash follicles                                  from obscuring line of incision.
    Intermarginal strip is 2 mm flat strip lies       • Wounds should not be extended to explore
between anterior and posterior edge. It is               structures unless the exploration is for
covered with stratified squamous epithelium              suspected foreign body.
which forms transition between skin and               • Extensive lid laceration can lead to damage to
conjunctiva. The sharp posterior border lies in          orbital septum. While repairing lid orbital
contact with the ocular surface and responsible          septum should not be sutured.
for proper spreading of tears. Immediately            • Lid has excellent blood supply which allows
anterior to posterior border, ducts of meibomian         tissue to survive as free graft. During
glands open in a single row. Gray line lies              primary repair tissue should be preserved as
anterior to meibomian gland openings and                 much as possible. Do not unnecessarily cut
represents avascular plane between orbicularis           or freshen the wound edges.
and the tarsus plate. It is the plane along with      • Preferably do not add tissue at the time of
lid can be spilt into two halves.                        primary repair unless cornea is at risk. Wait
    Anterior and Posterior lamella[3]                    for wound to settle for 3, 6 or 9 months
    Functional anatomy of the lid can be                 before repairing defects
simplified by dividing lid into two parts along
gray line. Eyelid skin and orbicularis muscle         Tissues Available for Reconstructions
forms anterior lamella while conjunctiva and              Similar tissue should be used for
tarsal plate forms posterior lamella.                 reconstruction [Table 1]. Color match is
    While repairing the lid, meticulous               important for cosmesis of anterior lamella. A
reconstruction of anterior and posterior lamella      full thickness skin graft which can match the
color should be chosen. When larger grafts         Free skin grafts[4]
are required, split skin grafts can be utilized.       Free skin grafts are harvested from a donor
The lining or the posterior lamella coming         site and transferred to fill an anterior lamellar
in contact with the globe should be smooth,        defect. Vascular supply to the free graft must
capable of producing mucus for lubrication.        be provided by recipient site for the graft to
                      Table 1                      survive.
                                                          Full thickness skin graft (FTSG) employs
                                                          entire thickness of epidermis and dermis
                                                      harvested from donor site. Upper eyelid skin
                                                     is the best choice for reconstruction of eyelid
                                                          defects. Other sites for harvesting FTSG
Donor tissue for reconstruction                         include retroauricular or pre auricular skin,
   Spinelli and Jelks had divided the               supraclavicular skin and upper inner arm skin.
periocular reconstructions into five zones, with       Split thickness skin graft (STSG) is seldom
their own anatomic, functional, and esthetic       used in eyelid reconstruction. It is useful when
consideration. It is simpler to denote each area   a large area of skin needs to be covered and no
by its name.[5]                                          myocutaneous flap can be mobilized. With
                                                       STSG, the colour, texture and thickness are
Techniques of Lid Repair                           often a poor match for eyelid skin.
  Anterior lamellar defects not involving lid
margin[6]                                          Eye lid margin repair[4,6]
                                                       Eyelid laceration involving lid margin
Primary closure with undermining                   requires meticulous approximation to avoid
    Primary closure can be performed if            notching which cause functional and cosmetic
redundant skin exists adjacent to the defect.      problem. The wound should be carefully
Meticulous closure without tension is              inspected to identify tarsus and lid margin
attempted. If required undermining of the          landmarks like gray line, anterior lash line
surrounding skin done to mobiles skin for          and posterior margin. If wound is ragged,
adequate closure.                                  freshening the edges with a scalpel blade may
    As eyelid skin has extensive blood supply,     aid in structure recognition and apposition.
even apparently necrotic eyelid skin survives      Repair should be carried out preferably under
after repair. Preservation of tissue done by       operating microscope.
avoiding unnecessary excision.                         Repair of lid margin is done with three
                                                   vertical mattress sutures using a non-
Myocutaneous flaps                                 absorbable 6-0 silk on a cutting needle. The
    Myocutaneous flaps in the periocular area      first bite is taken in the plane of meibomian
are formed of skin and orbicularis muscle that     glands approximately 3 mm from wound
is dissected off the underlying orbital septum     edge and 3 mm deep. The superficial bites
and stretched into position over the anterior      are placed 1.5 mm behind and below the lid
lamellar defect. Because myocutaneous flap         margin. The suture is pulled to determine
uses tissue adjacent to defect, the match for      whether a satisfactory approximation of the
colour and texture is good.                        margin edges has occurred. A good apposition
                                                   with slight margin eversion should be the
goal. Two more sutures are passed in front and       accomplished for injuries that have up to 40%
behind to approximate anterior and posterior         tissue loss. However, it is often necessary
lid margin. These sutures are tied and left long.    to “freshen up” the eyelid margins prior to
The tarsus is next closed with fine, interrupted,    reconstruction.
partial-thickness sutures, such as 6-0 Vicryl.
The anterior lamella of the eyelid is closed         Lateral canthotomy and cantholysis[4]
next, with interrupted sutures using 6-0 silk.           When direct closure is attempted, additional
The long margin sutures are tied through these       horizontal lengthening is provided by lateral
skin sutures to prevent the suture ends from         canthotomy and cantholysis. In lateral
abrading the cornea (Figure 2). Sutures are          canthotomy, horizontal limb of Y shaped lateral
removed after approximately 2 weeks.                 canthal ligament is incised. For cantholysis,
                                                     inferior or superior crus of lateral canthal
                                                     tendon is incised and separated from the bony
                                                     attachment and lid mobilized. Technique is
                                                     particularly useful to prevent suturing under
                                                     tension where laxity of tissue is less.
                          I
                                t is our immense pleasure to invite you to the 43rd Annual Meeting of
                                the Indonesian Ophthalmologists Association (IOA) held in Padang,
                                West Sumatera, August 30th - September 1st, 2018. It is such an honor
                           for West Sumatera IOA to be chosen to host the Annual Meeting of IOA,
                           which is an annual scientific and professional ophthalmologists event. This
                           conference is a collaboration of all subspecialty fields of ophthalmology
                           who aims to share knowledge and skills that will be influential in improving
                           the quality of eye care services.
  We are inviting experts from all fields of ophthalmology with an emphasis on innovation, eye
care, surgical technique and most developed technology with a clear objective to prepare current eye
practitioners for the ever-evolving future of eye care.
  Padang is the gate to the beauty of Minangkabau tourisms. Needless to say that West Sumatera is
well known as one of the most attractive provinces to foreigners for its exotic beaches, mountains
and interesting traditions as well as traditional culinary which are internationally recognized. The
uniqueness of its culture has become a compelling attraction to people from all around the world.
  We are proud to invite all of you to enjoy the natural attractions of our city and have a taste of our
famous spicy culinary.
  We look forward to welcoming you to Padang, West Sumatera in August 2018.
  Heksan, MD
 • Head of IOA Padang
 • Chairman of 43rd Annual Scientific Meeting of IOA in Padang
                                                     6
                          Dear Friends and Colleagues,
                          I
                                t is with great pleasure that I greet you welcome to the 43rd Indonesian
                                OphthalmologistsAssociation annual meeting. This year we are meeting
                                in the beautiful city of Padang. Our colleagues from IOA Sumatra Barat
                           has worked so hard to continue our tradition and commitment in the field
                           of ophthalmology, and this year the theme of the meeting is “Innovations
                           in Ophthalmology Practices”. Technical and skill innovations have always
                           been an area of interest for many of clinicians in ophthalmology, due to its
                           practical use in the everyday services to our patients. Innovations in the area
of teleophthalmology has recently gained international attention as a branch of telemedicine. The
application of teleophthalmology in the future is limitless, from diagnostics, outcome predictions,
and overall patients’ personalized managements. We encourage teaching institutions to continue
working on their research and conduct studies that produces big data. Big data management will
require special software, and the development of artificial intelligence (AI) in ophthalmology could
assist its analysis and eventually integrated them to teleophthalmology. It is best to anticipate these
challanging advancement in technology will be available in the near future. It remains a challenge,
for in every new advancement in technology, an ethical concern would usually arise. Authenticity
and copyright of the original research should always be protected, ownership guarded, and is often a
challenge that we need to always keep an awareness of.
  Towards the end of 2019 we are expected to prepare our report for the WHO Vision 2020 initiatives.
According to the Rapid Assessment of Avoidable Blindness (RAAB) conducted in 2014-2016, the
main cause of blindness in most Indonesian area (around 15 province in total), is indeed cataract.
Intervention has been ongoing, and hopefully in the remaining time we can continue to increase
the quality and quantity of cataract surgery with good patient selection and contributed further to
lowering the number of cataract blindness. We are hopeful that with this initiative, the cataract
numbers in Indonesia will reduce significantly and improve our people’s overall health.
  I would like to extend our heartfelf thank you to all Indonesian and international faculty, and also
to the hardworking Perdami Sumatera Barat with their organizing committee for all the energy, time
and passion. To the participating ophthalmic and medical/pharmaceuticals industry, thank you for
your continued support throughout the years. And lastly, our spirits are high and full with gratitude,
for this scientific meeting will not be possible without the blessing of Allah SWT, and with collective
efforts and commitment from all parties mentioned. We are hopeful that this will become a joyful
and productive meeting, that our attendees and participant could bring home as an unforgettable
experience with lasting memories.
  Sincerely Yours,
  M. Sidik, MD
  President Indonesian Ophthalmologists Association (Perdami)
                                                  7
ADVISOR
    •   Wirsma Arif, MD
    •   M. Sidik,MD
    •   M. Kautsar Boesoirie, MD
    •   Khalilul Rahman, MD
    •   Ari Djatikusumo, MD
    •   Julie D. Barliana, MD
    •   Syntia Nusanti, MD
    •   Susanti Natalya Sirait, MD
    •   Syarif Amal, MD
    •   Ardizal Rahman, MD
CHAIRMAN
• Heksan, MD
VICE CHAIRMAN
• Syahrial Haroes, MD
SECRETARY
• Havriza Vitresia, MD
VICE SECRETARY
    • Mayasari Nasrul, MD
    • Fitriliza Hamdy, MD
TREASURE
• Afiyarni Ibrahim, MD
SCIENTIFIC
                                           10
SCIENTIFIC TEAM
    •   Hendriati, MD (Coordinator)
    •   Khalilul Rahman, MD
    •   Muslim, MD
    •   Yaskur Syarif, MD
    •   Ardizal Rahman, MD
    •   Getry Sukmawati, MD
    •   Kemala Sayuti, MD
    •   M. Hidayat, MD
    •   Syahrial Haroes, MD
    •   Heksan, MD
    •   Harmen, MD
    •   Andrini Ariesti, MD
    •   Mardijas Efendi, MD
    •   Weni Helvinda, MD
    •   Fitratul Ilahi, MD
    •   Havriza Vitresia, MD
    •   Rinda Wati, MD
    •   Julita, MD
    •   Yanuhardi, MDYandrison, MD
    •   Yanuhardi, MD
                                      11
                                                                 CONTENTS
Content ........................................................................................................................................ 13
INASCRS
Pearl On Posterior Capsular Opacity ....................................................................................... 35
Indri Wahyuni, MD
                                                                            14
Fashioned Corneal Donor : One for two .................................................................................. 87
Dini Dharmawidiarini, MD
INAVRS
New Modality Imaging In Diabetic Retinopathy..................................................................... 143
Sauli Ari Widjaja, MD
                                                               15
Choice of Intraocular Tamponade................................................................................................. 155
Arief Wildan, MD
IGS
Glaucoma: Rate of Progression................................................................................................. 185
Fifin Luthfia Rahmi, MD
                                                                       16
Maintaining Bleb AfterTrabeculectomy ................................................................................. 219
Fitratul Ilahi, MD
Low-cost nonvalved drainage device to control the neovascular glaucoma ........................ 283
Erin Arsianti, MD
                                                                  17
Silicone Oil Induced Glaucoma in Pregnancy ......................................................................... 289
Nelandriani Yudapratiwi, MD
INOIIS
How to use and when to strat steroid and NSIAD in Ocular surface problems ................... 293
Ratna Sitompul, MD
Blepharitis: What Is It and How Does It Impact Your Eyes ?................................................ 305
Fatma Asyari, MD
Sterile and Infectious Corneal Ulcer, How Do We Distinguish Both Of Them? ................... 315
Havriza Vitresia, MD
Auto Inflammatory And Auto Immune Diseases : Diagnosis And Treatment........................ 323
Prof. P.M Van Hagen, MD
                                                                    18
Septic Cavernous Sinus Thrombosis......................................................................................... 329
Getry Sukmawati, MD
                                                                   19
The Essential Path To Get Definitive Diagnosis Of Uveitis ..................................................... 411
Rifna Lutfiamida, MD
INAPOSS
Assessment visual acuity in children; which method? ............................................................ 429
Rusdianto, MD
                                                                      20
Membranous Conjunctivitis in Children ................................................................................ 477
Kemala Sayuti, MD
                                                                  21
Levator Resection in Ptosis ........................................................................................................ 521
Hernawita Suharko, MD
                                                                           22
Penanganan Kelainan Soket ...................................................................................................... 579
Darmayanti Siswoyo, MD
INARVOS
The Issues of Controling Myopia Progression and Its Risk Factors ..................................... 619
Christina Aritonang, MD
                                                                    23
When to Use Toric SCL / RGP for Astigmatism Correction ................................................. 639
Sagung Gede Indrawati, MD
INANOS
The Role Of Neuroprotective In Ischemic Optic Neuropathy ................................................ 683
Bobby Sitepu, MD
                                                                      24
Single Oculomotor Nerve Palsy Management ......................................................................... 707
Lukisiari Agustini, MD
Which One is The Trouble: The Big or Small One ? ............................................................... 719
Devi Azri Wahyuni, MD
OPHCOM
Strengthening Eye Care System at District Level: Learning from the
„Inclusive System for Effective Eye Care‟ (I-SEE) Project ..................................................... 749
Manfred Moerchen, MD
                                                                25
Provincial Planning based on RAAB Result and District Model ........................................... 767
Implementation
Syumarti, MD
Ethic
Etika dan Protokol Pemberian Informasi Kepada Pasien Dengan Prognosis Buruk .......... 803
Dr. Siswanto, SpM., SpKL
BANK MATA
Present Situation of Indonesian Eye Bank System .................................................................. 809
Tjahjono D. Gondhowiardjo, MD
                                                                      26
Peran Keberadaan Bank Mata pada Pusat Pendidikan Dokter Spesialis Mata .................. 811
Prof. Suhardjo Pawiroranu, MD
Corneo-scleral Rim Excision Training and It‟s Preservation Requirements ........................ 817
Kukuh Prasetyo, MD
ARSAMI
Universal Health Coverage and Universal Eye Health In Eye Hospital Perspective ........... 827
Rastri Paramita, MD
                                                                                REFERENCES
                                                                                1. Sirbamanian N. Reconstruction of eyelid defect.Indian
in conjunction with an adequate mucosal                                             Journal of Plastic Surgery. 2011. 44(10: 5-13
lining posteriorly. A deep inverted triangle                                    2. Mustak H. In: Ocular Trauma: Principles and Practice,
must be excised below the defect to allow                                           Kuhn F, Pieramici D. New York. Thieme, 2002. p.38-
                                                                                    52
adequate rotation of the flap. The side of the                                  3. Vichare N. Management of Lid Laceration. Ocular
triangle nearest the nose should be                                                 Trauma. DOS Times - Vol. 20, No. 8 February,
practically vertical. The advantage of this                                         2015;33-38
                                                                                4. Sushil Kumar, Sima Das , Zia Chaudhuri, Vandana
procedure is that it is a one-stage, complete
                                                                                    Kohli. Basic Principles of Lid Repair and
lower lid reconstruction.                                                           Reconstruction. DOS Times September, 2006;3:210-
                                                                                    14.
                                                                                5. Spinelli HM, Jelks GW. Periocular reconstruction:
                                                                                    A       systematic      approach. Plast       Reconstr
CONCLUTION                                                                          Surg. 1993;91:1017–24. [PubMed]
                                                                                6. Christine C. Nelson Review of management of eyelid
    Repairing of eyelid defect requires                                             trauma. Australian and New Zealand Journal of
knowledge and meticulous approach. Gentle                                           Ophthalmology 1991;4: 357-63.
tissue handling and proper alignment should                                     7. Carroll RP. Management of eyelid trauma. In: Hornblass
                                                                                    A, ed. Oculoplastic orbital, and reconstructive surgery.
be done. Aim should be to achieve best                                              Baltimore: Williams & Wilkins, 1988;45:409-414.
possible functional and cosmetic outcome.
There are various techniques available for
reconstructions of defects of eyelids starting
from the spontaneous healing after excising
the lesion. While choosing a method, the
specific function of the area of the eyelid has
to be kept in mind. As eyes are the focal
point of the face, acceptable cosmesis in
reconstruction should be a major requisite.
                                                                       27