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Ondansetron Clinical Medications Guide

This clinical form provides information on the generic and trade names, classification, dosing, administration, and nursing considerations for the antiemetic medication ondansetron (Zofran). It lists the drug's mechanism of action in blocking serotonin receptors to treat nausea and vomiting, potential interactions, and importance of assessing for nausea before and after administration and monitoring for extrapyramidal side effects. The nursing process focuses on evaluating the effectiveness of ondansetron in preventing nausea and when to hold administration based on the patient's condition.

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4K views3 pages

Ondansetron Clinical Medications Guide

This clinical form provides information on the generic and trade names, classification, dosing, administration, and nursing considerations for the antiemetic medication ondansetron (Zofran). It lists the drug's mechanism of action in blocking serotonin receptors to treat nausea and vomiting, potential interactions, and importance of assessing for nausea before and after administration and monitoring for extrapyramidal side effects. The nursing process focuses on evaluating the effectiveness of ondansetron in preventing nausea and when to hold administration based on the patient's condition.

Uploaded by

E
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as DOC, PDF, TXT or read online on Scribd
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NURS 1566 Clinical Form 3: Clinical Medications Worksheets

(You will need to make additional copies of these forms)

Generic Name Trade Name Classification Dose Route Time/frequency


ondansetron Zofran antiemetics 4-8 mg IVP Q 6 hrs PRN
Peak Onset Duration Normal dosage range
15-30 min rapid 4-8 hrs 4 mg before induction of anesthesia or postoperatively

Why is your patient getting this medication For IV meds, compatibility with IV drips and/or
Nausea solutions
Administer undiluted immediately before induction of
anesthesia or postoperatively if nausea and vomiting occur
shortly after surgery, Dilute doses for prevention of nausea
and vomiting associated with chemotherapy in 50 ml of
D5W, 0.9% NaCl, D5/0.9% NaCl, D5/0.45% NaCl.
Solution is clear and colorless. Stable for 7 days at room
temperature following dilution.
Mechanism of action and indications Nursing Implications (what to focus on)
(Why med ordered) Contraindications/warnings/interactions
Blocks the effects of serotonin at 5-HT3-receptor Hypersensitivity,
sites (selective antagonist) located in vagal nerve
terminals and the chemoreceptor trigger zone in the L
CNS. i
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Interactions with other patient drugs, OTC or Lab value alterations caused by medicine
herbal medicines (ask patient specifically) May cause transient ↑ in serum bilirubin, AST, and ALT
None known for this patient levels.
Be sure to teach the patient the following about this
medication
Instruct patient to take ondansetron as directed, Advise
patient to notify health care professional immediately if
involuntary movement of eyes, face, or limbs occurs.

Nursing Process- Assessment Assessment Evaluation


(Pre-administration assessment) Why would you hold or not give this Check after giving
Assess patient for nausea, vomiting, med? Prevention of nausea.
abdominal distention, and bowel sounds No nausea or vomiting.
prior to and following administration.
Assess patient for extrapyramidal effects
(involuntary movements, facial
grimacing, rigidity, shuffling walk,
trembling of hands) periodically during
therapy.

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