Administrative Order 2022-0010:
Guidelines on TB-HIV Services
         Integration for Universal Health
           Care (UHC) Implementation
Department of Health, Philippines
Rationale
                           Universal Health Care Act
    PhilSTEP1 2020-2023
     Integrated patient-   Guidelines                     Phil Health Sector HIV
                                                         Strategic Plan 2020-2022
        centered care                                  Innovative and differentiated
    TB-HIV collaboration    TB-HIV                        approach for treatment
                             DOH AO 2014: TB-HIV
                                 Collaboration
                              (amended AO 2008-
                                     0022)
Key changes from 2014 DOH AO on TB-HIV:
1. CBNAAT (Gene Xpert) as diagnostic platform for TB and point of
   care Viral Load testing for HIV
2. Shorter regimens for TB preventive treatment
3. Emphasis on patient-centered care or differentiated care,
   home/community-based care, digital adherence technologies (DAT)
4. Optimizing TB and HIV resources
5. Clearer delineation in procurement of commodities (DOH,
   hospitals, LGU)
Objective
• To provide standards and mechanisms for collaboration between the
  NTP and NASPCP for the provision of TB and HIV services under the
  Universal Health Care
 Scope and Coverage
• All health facilities, both   • Providing TB and HIV services
  public and private               •   Screening
                                   •   Diagnosis
                                   •   Treatment
                                   •   Prevention
General Guidelines
   Provide integrated TB and HIV services to all patients and ensure
   appropriate referral of cases within the health care provider
   network (HCPN)
   DOH and LGU shall ensure adequate commodities
   Resources shall be pooled and harmonized thru SHF to ensure
   efficiency, prevent catastrophic cost to patient, and avoid
   overlapping
   HCW shall be capacitated to provide both TB and HIV services
   according to standards
General Guidelines
 Appropriate and timely TB and HIV treatment shall be given
 A data-sharing agreement shall be issued to ensure rational
 sharing of data to better manage both programs while
 maintaining confidentiality and security of data
 Infection prevention and control measures shall be strictly
 observed
Specific Guidelines
Prevention                 Treatment
Detection                  Provision of commodities
Infection Prevention and   Capacity building
Control
PREVENTION
⮚ TB Preventive Treatment (TPT) for PLHIV and TB close contacts
  • referred to the NTP MOP, 6th. ed. for the new TPT regimens (shorter
     regimens)
⮚Education, counseling, social communication on prevention as
 part of comprehensive care
⮚HIV prevention commodities (condoms and lubricants) shall be
 appropriately provided to TB and HIV patients
⮚Existing service delivery networks shall be maximized for
 advocacy, demand-generation and implementation of other TB-
 HIV related activities
ANNEX A. Regimens for TB Preventive Treatment
   Regimen            Drugs                Dosing and Duration
  3HP         Isoniazid, Rifapentine   Weekly for 12 weeks (3months)
  3HR         Isoniazid, Rifampicin    Daily for 3 months
  4R          Rifampicin               Daily for 4 months
  6H          Isoniazid                Daily for 6 months
DETECTION
⮚Bi-directional screening
   ✔PLHIV
      • screened for TB symptoms during every visit
      • CxR upon diagnosis then annually
   ✔ TB patients at least 15 years old offered HIV testing services
⮚Use of NAAT/Xpert as primary diagnostic tool for TB and for point-of-care HIV
 viral load testing among PLHIV on ART
   ✔Laboratory network analysis to determine optimal number of NAAT
   ✔LGU-CHD coordination for recommended TB and HIV laboratory sites within the referral
     network
   ✔ Specimen transport systems optimized - for TB test (sputum), for HIV test (blood), for
     transport of results
⮚Public and private providers mandated to report diagnosed TB and HIV patients
 using available platforms (ITIS, OHASIS)
Annex B.
Algorithm
for TB
Screening
among
PLHIV
INFECTION PREVENTION AND
CONTROL
⮚ Minimum public health
 standards
⮚Administrative controls,
 engineering controls and use of
 PPEs based on facility risk
 assessment
TREATMENT
⮚ Patients with TB, HIV, and TB-HIV co-infection given TB treatment and
 ART according to DOH standards
   ✔Standard regimens for drug-susceptible and drug-resistant TB
   ✔ART initiated within same day of recognition of HIV infection regardless of clinical
    and immunologic status
   ✔Prevention of other opportunistic infections among PLHIV (DM 2020-0338)
⮚Treatment adherence support and counseling
⮚Patient-centered care and differentiated service delivery : home- or
 community-based care
   ✔ When available, digital adherence technologies shall be   used
⮚Active drugs safety monitoring and management (aDSM)
Annex D.
                        OPPORTUNISTIC INFECTIONS                           DM 2020-0338 pages
                1.   Pneumocystis Pneumonia                                      7 - 21
Annex E.        1.   Bacterial Pneumonia                                        22 - 44
Opportunistic   1.   Cryptococcal Meningitis                                    45 – 63
Infections      1.   Candidiasis                                                64 - 74
                1.   Cytomegalovirus Disease                                    75 – 88
                1.   Parasitic Infections
                a.   Toxoplasmosis                                                 89 - 103
                a.   Microsporidiosis                                             104 - 110
                a.   Cyclosporiais                                                111 – 116
                a.   Cryptosporidiosis                                            117 – 122
                a.   Strongyloidiasis                                             122 - 128
                1.   Mycobacterium avium Complex                                  129 - 137
    DOH Department Memorandum 2020-0338: Adoption of PSMID Clinical Practice Guidelines on the Prevention,
    Diagnosis and Treatment of Opportunistic Infections in Human Immunodeficiency Virus Infected Adults and
    Adolescents in the Philippines (file can be accessed through this link: https://bit.ly/3r4POIT)
 Provision of Commodities                                      Local Government Units
                                                                           • Chest X-ray
DOH-Central Office                               • Specimen containers (sputum cups,
• Cartridges for Xpert TB test                                               blood vials)
• HIV point of care Viral load (VL)                                       • Glass slides
  cartridges                                                      • Staining kits (DSSM)
• HIV testing kits                                                       • PPD (for TST)
• CD4 cartridges                                • Cartridges for TB and HIV (augment)
• First line anti-TB drugs (adults and            • HIV viral load cartridges (augment)
  children)                                                • HIV testing kits (augment)
• selected second line anti-TB drugs                    • CD4 cartridges (augmentation
• Drugs for anti-retroviral therapy                  • Azithromycin (devolved in 2023)
• Drugs for TB preventive treatment              • Condoms and lubricants (augment)
• Co-trimoxazole for Pneumocystis                                 • PPEs (augmentation
  pneumonia prophy-
                                              Health Facilities through OHAT
• Azithromycin for M. avioum prophy-     •   Consumables for HIV VL testing (e.g,
• Condoms and lubricants                               EDTA tubes, Cryo- vials)
                                                           • HIV VL cartridges
• Personal; Protective Equipment
                                                              • CD4 cartridges
Capacity Building
 • Health care workers (hospitals, RHU/HC, TB facilities, HIV
   Treatment Facilities) shall be trained in:
    a.   NTP Manual of Procedures, 6th. Ed. training
    b.   HIV counseling, testing and treatment
    c.   Use of Gene Xpert testing for both TB and HIV viral load
    d.   ITIS and OHASIS
    e.   Procurement and Supply Management
 Monitoring and Evaluation
• Standard Indicators                       • Data shall be reported
   1.   No. of TB patients with known HIV     following regular program
        status (tested for HIV)               procedures (ITIS, OHASIS)
   2.   No. of PLHIV screened for TB
   3.   No. of patients with TB-HIV co-     • Data sharing: ITIS and
        infection                             OHASIS
   4.   No. of PLHIV given TB Preventive
        Treatment
   5.   Treatment outcome: TB treatment
        and TPT                             • Integrated monitoring and
                                              PIR
• Other TB indicators and HIV
  indicators shall continue to be           • TB-HIV Technical Working
  monitored                                   Group – monitor program
                                              performance
Thank you.