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Vancomycin 2

Vancomycin is an antibiotic used to treat various bacterial infections. It works by inhibiting cell wall biosynthesis in gram-positive bacteria, preventing incorporation of amino acid chains into the peptidoglycan cell wall structure. Common uses include treating infections caused by staphylococci, enterococci, and diphtheroids. Side effects can include diarrhea, hearing loss, and kidney problems. Nurses monitor for side effects, assess renal function, and observe for signs of infusion reactions when administering vancomycin intravenously.

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26 views2 pages

Vancomycin 2

Vancomycin is an antibiotic used to treat various bacterial infections. It works by inhibiting cell wall biosynthesis in gram-positive bacteria, preventing incorporation of amino acid chains into the peptidoglycan cell wall structure. Common uses include treating infections caused by staphylococci, enterococci, and diphtheroids. Side effects can include diarrhea, hearing loss, and kidney problems. Nurses monitor for side effects, assess renal function, and observe for signs of infusion reactions when administering vancomycin intravenously.

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Generic Name-Vancomycin Trade Name- Firvanq, Vancocin

Mechanism of Action
The bactericidal action of vancomycin results primarily from inhibition of cell-wall Intended Use:
biosynthesis. Specifically, vancomycin prevents incorporation of N-acetylmuramic acid  Staphylococcus enterocolitis, Pseudomembranous colitis, Catheter-related
(NAM)- and N-acetylglucosamine (NAG)-peptide subunits from being incorporated into the infections
peptidoglycan matrix, which forms the major structural part of Gram-positive cell walls.  Endocarditis: Diphtheroid, Enterococcal, Staphylococcal,  and  Streptococcal species
Vancomycin forms hydrogen bonds with the terminal D-alanyl-D-alanine moieties of the
NAM/NAG-peptides, preventing the incorporation of the NAM/NAG-peptide subunits into  Staphylococcal infections: septicemia, skin and soft tissue infections, bone
the peptidoglycan matrix. In addition, vancomycin alters bacterial-cell-membrane infections, lower respiratory tract infections, etc.
permeability and RNA synthesis. (Vancomycin-stat pearls)
 Intra-abdominal infections due to MRSA or ampicillin-resistant enter Surgical-site.
(Ummu; 2021)

Common Side Effects: Nursing Considerations:


 increased diarrhea that is watery or bloody. Assessment:
 hearing loss, ringing in your ears.  Collect the health history and note any allergy to vancomycin.
 kidney problems - swelling, rapid weight gain, pain in your side or lower back, little  Assess for the interaction with any other antibiotics or medicines the client is taking,
or no urination; or Perform a baseline auditory assessment.
 low potassium level - leg cramps, constipation, irregular heartbeats, fluttering in  Assess vital signs and urine output, Confirm the client’s pregnancy or lactation
your chest, increased thirst or urination, numbness or tingling, muscle weakness or status, Obtain baseline CBC and RFTs.
limp feeling.( Ummu; 2021) Intervention:
 Monitor heart rate and BP throughout during administration of Vancomycin.
 Maintain strict intake and output chart and check for any changes in urination, urine
color, and pattern.
 Observe closely for signs (e.g., chills, fever, flushing of the neck, hypotension,
tachycardia, and nausea and vomiting) of red-man syndrome during IV infusion.

References:

Ummu. (2022, October 16). Vancomycin nursing implications: Patient teachings: MOA was. Nurseship.com. https://nurseship.com/vancomycin-nursing-implications-patient-teachings-moa/ 

Vancomycin - statpearls - NCBI bookshelf. (n.d.-b). https://www.ncbi.nlm.nih.gov/books/NBK459263/ 

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